日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Targeting polyamine metabolism and ferroptosis enhances the efficacy of KRAS-targeted therapy depending on KEAP1 status

靶向多胺代谢和铁死亡可增强KRAS靶向治疗的疗效，具体效果取决于KEAP1状态。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-65441-4
Bian, Yunyi; Shan, Guangyao; Bi, Guoshu; Xu, Zhijie; Liang, Jiaqi; Yan, Yuanliang; Guo, Wei; Sui, Qihai; Yi, Yanjun; Shi, Haochun; Lu, Tao; Zhang, Huan; Wang, Qun; Fan, Hong; Jiang, Wei; Zhan, Cheng
KEAP1
RAS
铁死亡
代谢
发表日期：2025
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NDRG1-Driven Lactate Accumulation Promotes Lung Adenocarcinoma Progression Through the Induction of an Immunosuppressive Microenvironment.

NDRG1驱动的乳酸积累通过诱导免疫抑制微环境促进肺腺癌进展

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202501238
Wu Gujie, Cheng Hongxia, Yin Jiacheng, Zheng Yuansheng, Shi Haochun, Pan Binyang, Li Ming, Zhao Mengnan, Liang Jiaqi, Bian Yunyi, Shan Guangyao, Bi Guoshu, Guo Weigang, Wang Lin, Huang Yiwei
免疫/内分泌
肺癌
发表日期：2025
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Sarcosine sensitizes lung adenocarcinoma to chemotherapy by dual activation of ferroptosis via PDK4/PDHA1 signaling and NMDAR-mediated iron export.

肌氨酸通过 PDK4/PDHA1 信号传导和 NMDAR 介导的铁输出双重激活铁死亡，使肺腺癌对化疗更加敏感

期刊:Experimental Hematology & Oncology
影响因子:13.5
doi:10.1186/s40164-025-00657-0
Shan Guangyao, Bian Yunyi, Ren Shencheng, Hu Zhengyang, Pan Binyang, Zeng Dejun, Zheng Zhaolin, Fan Hong, Bi Guoshu, Yao Guangyu, Zhan Cheng
信号转导
肺癌
铁死亡
发表日期：2025
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Transcription factor ZNF266 suppresses cancer progression by modulating CA9-mediated intracellular pH alteration in lung adenocarcinoma

转录因子ZNF266通过调节CA9介导的肺腺癌细胞内pH值改变来抑制癌症进展。

期刊:Respiratory Research
影响因子:5
doi:10.1186/s12931-025-03278-7
Ren, Shencheng; Zhu, Junkan; Shan, Guangyao; Liang, Jiaqi; Bian, Yunyi; Lin, Han; Shi, Haochun; Pan, Binyang; Zhao, Guangyin; Yang, Huiqin; Huang, Xiaolong; Zhan, Cheng; Ge, Di; Bi, Guoshu
CA9
细胞生物学
肿瘤
肿瘤免疫
发表日期：2025
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KLF13 promotes ferroptosis and chemosensitivity in lung adenocarcinoma.

KLF13 促进肺腺癌细胞的铁死亡和化疗敏感性

期刊:BMC Biology
影响因子:4.5
doi:10.1186/s12915-025-02303-x
Shi Haochun, Pan Binyang, Wu Gujie, Liang Jiaqi, Bian Yunyi, Shan Guangyao, Ren Shencheng, Bi Guoshu, Zhan Cheng, Guo Weigang
细胞生物学
肺癌
铁死亡
发表日期：2025
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Unveiling chemotherapy-induced immune landscape remodeling and metabolic reprogramming in lung adenocarcinoma by scRNA-sequencing

利用单细胞RNA测序揭示化疗诱导的肺腺癌免疫微环境重塑和代谢重编程

期刊:Elife
影响因子:6.4
doi:10.7554/eLife.95988
Huang, Yiwei; Wu, Gujie; Bi, Guoshu; Cheng, Lin; Liang, Jiaqi; Li, Ming; Zhang, Huan; Shan, Guangyao; Hu, Zhengyang; Chen, Zhencong; Lin, Zongwu; Jiang, Wei; Wang, Qun; Xi, Junjie; Yin, Shanye; Zhan, Cheng
肿瘤
肿瘤免疫
单细胞
代谢
代谢重编程
细胞生物学
免疫/内分泌
发表日期：2024
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Retinoic acid receptor alpha inhibits ferroptosis by promoting thioredoxin and protein phosphatase 1F in lung adenocarcinoma

视黄酸受体α通过促进硫氧还蛋白和蛋白磷酸酶1F在肺腺癌中抑制铁死亡

期刊:Communications Biology
影响因子:5.1
doi:10.1038/s42003-024-06452-7
Bian, Yunyi; Shan, Guangyao; Liang, Jiaqi; Hu, Zhengyang; Sui, Qihai; Shi, Haochun; Wang, Qun; Bi, Guoshu; Zhan, Cheng
信号转导
肿瘤
铁死亡
肿瘤免疫
发表日期：2024
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Identification of the relationship between single-cell N6-methyladenosine regulators and the infiltrating immune cells in esophageal carcinoma

食管癌中单细胞N6-甲基腺苷调节因子与浸润免疫细胞之间关系的研究

期刊:Heliyon
影响因子:3.6
doi:10.1016/j.heliyon.2023.e18132
Bian, Yunyi; Bi, Guoshu; Shan, Guangyao; Liang, Jiaqi; Yao, Guangyu; Sui, Qihai; Hu, Zhengyang; Zhan, Cheng; Chen, Zhencong; Wang, Qun
食管癌
单细胞
免疫/内分泌
肿瘤
细胞生物学
肿瘤免疫
发表日期：2023
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FSCN1 induced PTPRF-dependent tumor microenvironment inflammatory reprogramming promotes lung adenocarcinoma progression via regulating macrophagic glycolysis.

FSCN1 诱导的 PTPRF 依赖性肿瘤微环境炎症重编程通过调节巨噬细胞糖酵解促进肺腺癌进展。

期刊:Cellular Oncology
影响因子:4.8
doi:10.1007/s13402-022-00726-0
Huang Yiwei, Shan Guangyao, Yi Yanjun, Liang Jiaqi, Hu Zhengyang, Bi Guoshu, Chen Zhencong, Xi Junjie, Ge Di, Wang Qun, Tan Lijie, Jiang Wei, Zhan Cheng
肺癌
细胞生物学
巨噬细胞
TPR
PTPRF
肿瘤微环境
炎症
巨噬细胞
发表日期：2022
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Tumor-Associated Regulatory T Cells in Non-Small-Cell Lung Cancer: Current Advances and Future Perspectives

非小细胞肺癌中的肿瘤相关调节性T细胞：当前进展与未来展望

期刊:Journal of Immunology Research
影响因子:3.6
doi:10.1155/2022/4355386
Liang, Jiaqi; Bi, Guoshu; Shan, Guangyao; Jin, Xing; Bian, Yunyi; Wang, Qun
肺癌
肿瘤
T细胞
肿瘤免疫
T细胞
细胞生物学
免疫/内分泌
发表日期：2022
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