日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Quercetin improves retinal glycolysis to slow myopia progression through orchestrating the AKT/FOXO/HK2 axis

槲皮素通过调控AKT/FOXO/HK2轴改善视网膜糖酵解，从而减缓近视进展。

期刊:Redox Biology
影响因子:11.9
doi:10.1016/j.redox.2026.104139
Zhang, Ruixue; Zhang, Miao; Xie, Yunxiao; Wei, Huixia; Yang, Zhaohui; Wen, Ying; Hao, Jiawen; Du, Yongle; Yang, Yuanting; Yin, Xuewei; Zhang, Yinqiao; Jiang, Wenjun; Bi, Hongsheng; Guo, Dadong
信号转导
AKT
发表日期：2026
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miR-223-3p improves macrophage polarization balance and mitochondrial metabolism to ameliorate uveitis by orchestrating P65(Lys310) acetylation through RBPJ/HDAC1 axis

miR-223-3p通过RBPJ/HDAC1轴调控P65(Lys310)乙酰化，从而改善巨噬细胞极化平衡和线粒体代谢，进而缓解葡萄膜炎。

期刊:Cellular & Molecular Biology Letters
影响因子:10.2
doi:10.1186/s11658-026-00874-3
Peng, Yuan; Liu, Bin; Xu, Shuqin; Qu, Ruyi; Zhang, Ruixue; Wang, Congling; Liu, Yunfeng; Wei, Huixia; Tian, Qingmei; Zhang, Miao; Bi, Hongsheng; Yin, Xuewei; Guo, Dadong
巨噬细胞
HDAC1
表观遗传
巨噬细胞
信号转导
代谢
线粒体
乙酰化
细胞生物学
免疫/内分泌
发表日期：2026
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Single-cell sequencing reveals reversible glial remodeling in the visual cortex during visual deprivation and recovery

单细胞测序揭示了视觉剥夺和恢复过程中视觉皮层中可逆的胶质细胞重塑

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2026.1730619
Gong, Xiaoqi; Feng, Jiaojiao; Xu, Zhe; Xie, Yunxiao; Han, Yibo; Li, Jing; Tang, Guodong; Liu, Yuxi; Dong, Xiaoyun; Li, Shuhan; Zhang, Jun; Wang, Junru; Liu, Runxun; Song, Jike; Bi, Hongsheng
胶质细胞
细胞生物学
单细胞
发表日期：2026
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Targeting the Hedgehog Signaling Pathway in the Retina Using Quercetin-Loaded Lipid Nanoparticles for Myopia Control

利用槲皮素负载脂质纳米颗粒靶向视网膜中的 Hedgehog 信号通路控制近视

期刊:Translational Vision Science & Technology
影响因子:2.6
doi:10.1167/tvst.15.4.3
Zhao, Lianghui; Guo, Bin; Dong, Xiaoyun; Du, Yongle; Xu, Zhe; Song, Yifan; Feng, Jiaojiao; Zhang, Aiying; Qu, Yi; Song, Jike; Bi, Hongsheng
信号转导
Hedgehog
发表日期：2026
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Research progress on glycolytic reprogramming in ophthalmic diseases

眼科疾病中糖酵解重编程的研究进展

期刊:PeerJ
影响因子:2.4
doi:10.7717/peerj.20478
Gong, Xiaoqi; Feng, Jiaojiao; Han, Yibo; Tang, Guodong; Yin, Yixue; Li, Jing; Liu, Yuxi; Zhang, Jun; Song, Jike; Bi, Hongsheng
发表日期：2026
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Single-cell RNA sequencing reveals anterograde trans-synaptic degeneration and exacerbated synaptic remodeling in myopia.

单细胞 RNA 测序揭示近视中顺行跨突触退化和突触重塑加剧

期刊:Experimental and Molecular Medicine
影响因子:12.9
doi:10.1038/s12276-025-01489-y
Zhang Ruixue, Xie Yunxiao, Zhang Miao, Li Zhiheng, Guo Lijie, Wei Huixia, Li Xiaomeng, Xin Jizhao, Yang Zhaohui, Wen Ying, Hao Jiawen, Li Xianglin, Yin Xuewei, Jiang Wenjun, Bi Hongsheng, Guo Dadong
细胞生物学
单细胞
发表日期：2025
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Quercetin-loaded exosomes delivery system prevents myopia progression by targeting endoplasmic reticulum stress and ferroptosis in scleral fibroblasts.

槲皮素负载的外泌体递送系统通过靶向巩膜成纤维细胞中的内质网应激和铁死亡来阻止近视进展

期刊:Materials Today Bio
影响因子:10.2
doi:10.1016/j.mtbio.2025.101896
Zhao Lianghui, Dong Xiaoyun, Guo Bin, Song Jike, Bi Hongsheng
细胞生物学
外泌体
铁死亡
发表日期：2025
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Therapeutic effect of miR-30b-5p-loaded lentivirus on experimental autoimmune uveitis via inhibiting Notch signaling activation.

miR-30b-5p负载的慢病毒通过抑制Notch信号激活对实验性自身免疫性葡萄膜炎具有治疗作用

期刊:Journal of Translational Medicine
影响因子:7.5
doi:10.1186/s12967-025-06438-x
Yin Xuewei, Wei Huixia, Guo Lijie, Liu Bin, Peng Yuan, Zhou Mengxian, Qiu Yan, Qu Ruyi, Gao Yane, Wu Qiuxin, Jiang Wenjun, Bi Hongsheng, Guo Dadong
信号转导
Notch
炎症
发表日期：2025
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Proteomic and Phosphoproteomic Characteristics of the Retina, Choroid, and Sclera in Guinea Pigs with Form-Deprivation Myopia

豚鼠形觉剥夺性近视视网膜、脉络膜和巩膜的蛋白质组学和磷酸化蛋白质组学特征

期刊:Molecular & Cellular Proteomics
影响因子:5.5
doi:10.1016/j.mcpro.2025.101069
Song, Yifan; Xu, Zhe; Li, Hong-Tao; Xie, Yunxiao; Zhao, Lianghui; Feng, Jiaojiao; Luo, Anfeng; Dai, Jiajing; Li, Jing; Guo, Xinran; Song, Jike; Bi, Hongsheng
Guinea
发表日期：2025
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Evidence for M2 Muscarinic Receptor Antagonist Delay of Myopia Development Through Activation of Kir3.4 Channel in the Retina of Guinea Pigs.

M2毒蕈碱受体拮抗剂通过激活豚鼠视网膜中的Kir3.4通道延缓近视发展的证据

期刊:Investigative Ophthalmology & Visual Science
影响因子:4.7
doi:10.1167/iovs.66.9.5
Zhou Hong, Zhou Guimei, Yang Qin, Niu Jiahao, Wang Runzhe, Liu Huilan, Hou Suwen, Bi Hongsheng, Liao Xuan
Guinea
发表日期：2025
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