文献库，生知库 | 链接生命科学的每一步

日期影响因子

Persistent IFN-I signaling inhibits mitochondrial oxidative metabolism in CD8(+) T cells during HIV-1 infection under cART

在接受抗逆转录病毒疗法（cART）治疗的HIV-1感染患者中，持续的I型干扰素（IFN-I）信号传导会抑制CD8(+) T细胞的线粒体氧化代谢。

期刊:Cellular & Molecular Immunology

影响因子:19.8

doi:10.1038/s41423-026-01398-8

Cheng, Liang; Li, Guangming; Luo, Fei; Bi, Wenwen; Lu, Mengmeng; Liu, Na; Zhao, Qiuchen; Han, Runpeng; Wang, Hongyu; Yang, Hao; Ma, Jianping; Hu, Wenjia; Yu, Haisheng; Hou, Wei; Xiong, Yong; Goonetilleke, Nilu; Jones, R Brad; Su, Lishan

免疫/内分泌

细胞生物学

发表日期：2026

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A Dual-Targeting Peptide Inhibitor Simultaneously Blocking Viral Attachment and Membrane Fusion for Broad-Spectrum Inhibition of SARS-CoV-2

一种双靶向肽抑制剂可同时阻断病毒附着和膜融合，从而广谱抑制SARS-CoV-2病毒。

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms26125729

Bi, Wenwen; Zhu, Tao; Xu, Yawen; Li, Jianmin

发表日期：2025

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Novel Engineered SARS-CoV-2 HR1 Trimer Exhibits Improved Potency and Broad-Spectrum Activity against SARS-CoV-2 and Its Variants

新型工程化SARS-CoV-2 HR1三聚体对SARS-CoV-2及其变种表现出更高的效力和广谱活性

期刊:Journal of Virology

影响因子:3.8

doi:10.1128/jvi.00681-22

Bi, Wenwen; Chen, Guilin; Dang, Bobo

发表日期：2022

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Rapid Optical Biosensing of SARS-CoV-2 Spike Proteins in Artificial Samples.

快速光学生物传感技术检测人工样本中的SARS-CoV-2刺突蛋白

影响因子:3.5

doi:10.3390/s22103768

Tao Ying, Bian Sumin, Wang Pengbo, Zhang Hongyong, Bi Wenwen, Zhu Peixi, Sawan Mohamad

发表日期：2022

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Engineered trimeric ACE2 binds viral spike protein and locks it in "Three-up" conformation to potently inhibit SARS-CoV-2 infection

经基因工程改造的三聚体ACE2可结合病毒刺突蛋白并将其锁定在“三聚体”构象，从而有效抑制SARS-CoV-2感染。

期刊:Cell Research

影响因子:25.9

doi:10.1038/s41422-020-00438-w

Guo, Liang; Bi, Wenwen; Wang, Xinling; Xu, Wei; Yan, Renhong; Zhang, Yuanyuan; Zhao, Kai; Li, Yaning; Zhang, Mingfeng; Cai, Xia; Jiang, Shibo; Xie, Youhua; Zhou, Qiang; Lu, Lu; Dang, Bobo

发表日期：2021

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IgG Fc-binding motif-conjugated HIV-1 fusion inhibitor exhibits improved potency and in vivo half-life: Potential application in combination with broad neutralizing antibodies

IgG Fc结合基序偶联的HIV-1融合抑制剂表现出更高的效力和更长的体内半衰期：有望与广谱中和抗体联合应用

期刊:PLoS Pathogens

影响因子:4.9

doi:10.1371/journal.ppat.1008082

Bi, Wenwen; Xu, Wei; Cheng, Liang; Xue, Jing; Wang, Qian; Yu, Fei; Xia, Shuai; Wang, Qi; Li, Guangming; Qin, Chuan; Lu, Lu; Su, Lishan; Jiang, Shibo

发表日期：2019

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Nonneutralizing Antibodies Induced by the HIV-1 gp41 NHR Domain Gain Neutralizing Activity in the Presence of the HIV Fusion Inhibitor Enfuvirtide: a Potential Therapeutic Vaccine Strategy

由 HIV-1 gp41 NHR 结构域诱导的非中和抗体在 HIV 融合抑制剂恩夫韦地存在下获得中和活性：一种潜在的治疗性疫苗策略

期刊:Journal of Virology

影响因子:3.8

doi:10.1128/JVI.00791-15

Wang, Qian; Bi, Wenwen; Zhu, Xiaojie; Li, Haoyang; Qi, Qianqian; Yu, Fei; Lu, Lu; Jiang, Shibo

发表日期：2015

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Receptor binding domain based HIV vaccines

基于受体结合域的HIV疫苗

期刊:Biomed Research International

影响因子:2.3

doi:10.1155/2015/594109

Liu, Huan; Bi, Wenwen; Wang, Qian; Lu, Lu; Jiang, Shibo

发表日期：2015

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