日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Effects of CT-388, a once-weekly signaling-biased dual GLP-1/GIP receptor agonist, on weight loss and glycemic control in preclinical models and participants with obesity

CT-388 是一种每周一次给药的信号传导偏向型双重 GLP-1/GIP 受体激动剂，本研究探讨了其对临床前模型和肥胖患者体重减轻和血糖控制的影响。

期刊:Molecular Metabolism
影响因子:6.6
doi:10.1016/j.molmet.2025.102291
Chakravarthy, Manu V; Rodriguez, Ruben; Hergarden, Anne; Elliott, Michael A; Frias, Juan P; Argüelles-Tello, Federico A; Tenorio, Edgar; Rankin, Jonathan E; Wu, Jingtao; Krishnan, Shyam; Erlanson, Daniel A; Fucini, Raymond V; Bone, Derek; Iwig, Jeffrey S; Acosta, Luis; Untereiner, Ashley; Pant, Asmita; Patton, Avalon; Sanchez-Sanchez, Leyla L; Luo, Jian; Steinberg, Alexandra; Bialonczyk, Damian; Hansen, Stig K
GLP-1
信号转导
代谢
GIP
肥胖
发表日期：2026
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Efficacy and safety of CT-868, a novel, fully biased, dual glucagon-like peptide-1/glucose-dependent insulinotropic polypeptide receptor agonist, in type 2 diabetes: A double-blind, randomized placebo controlled phase 2 trial

CT-868（一种新型的、完全偏向性的双重胰高血糖素样肽-1/葡萄糖依赖性促胰岛素多肽受体激动剂）治疗2型糖尿病的疗效和安全性：一项双盲、随机、安慰剂对照的II期试验

期刊:Diabetes Obesity & Metabolism
影响因子:5.7
doi:10.1111/dom.70006
Chakravarthy, Manu V; Elliott, Michael A; Acosta, Luis; Sonnenberg, Gabriele E; Bialonczyk, Damian; Wu, Jingtao; Argüelles-Tello, Federico A; Garcia-Reza, Raymundo; González-González, José Gerardo; Hansen, Stig K; Frias, Juan P
代谢
糖尿病
信号转导
免疫/内分泌
发表日期：2026
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Biased agonism of GLP-1R and GIPR enhances glucose lowering and weight loss, with dual GLP-1R/GIPR biased agonism yielding greater efficacy.

GLP-1R 和 GIPR 的偏向性激动作用可增强降血糖和减肥效果，而 GLP-1R/GIPR 的双重偏向性激动作用可产生更大的疗效

期刊:Cell Reports Medicine
影响因子:10.6
doi:10.1016/j.xcrm.2025.102156
Rodriguez Ruben, Hergarden Anne, Krishnan Shyam, Morales Marikris, Lam Davina, Tracy Ted, Tang Teresa, Patton Avalon, Lee Craig, Pant Asmita, Erlanson Daniel A, Enquist Johan, Bone Derek, Fucini Ray, Bialonczyk Damian, Hansen Stig K, Luo Jian, Chakravarthy Manu V
其它
发表日期：2025
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Balancing accuracy and cost in machine learning models for detecting medial vascular calcification in chronic kidney disease: a pilot study

平衡机器学习模型在检测慢性肾脏病中层血管钙化方面的准确性和成本：一项初步研究

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-025-02457-2
Bialonczyk, Urszula; Debowska, Malgorzata; Dai, Lu; Qureshi, Abdul Rashid; Bobrowski, Leon; Soderberg, Magnus; Lindholm, Bengt; Stenvinkel, Peter; Lukaszuk, Tomasz; Poleszczuk, Jan
心血管
发表日期：2025
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Personalized pulse wave propagation modeling to improve vasopressor dosing management in patients with severe traumatic brain injury

个性化脉搏波传播模型用于改善重度创伤性脑损伤患者的血管加压药剂量管理

期刊:PLoS Computational Biology
影响因子:3.6
doi:10.1371/journal.pcbi.1013501
Wolos, Kamil; Pstras, Leszek; Bialonczyk, Urszula; Debowska, Malgorzata; Dabrowski, Wojciech; Siwicka-Gieroba, Dorota; Poleszczuk, Jan
神经科学
发表日期：2025
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Characteristics and Weight Loss Practices From a Cohort of 20,000 Patients Using Direct-to-Consumer Telehealth: Observational Cross-sectional Study

一项针对20000名使用直接面向消费者的远程医疗患者的队列研究：特征和减肥实践——观察性横断面研究

期刊:JMIR Formative Research
影响因子:2.1
doi:10.2196/40062
Horn, Deborah Bade; Pash, Elizabeth; Zhou, Megan S; Broffman, Lauren; Bialonczyk, Damian; Doron, Tzvi; Chiquette, Elaine
发表日期：2023
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A Review of Emerging Technologies in Diabetes Management for Multiple-Dose Insulin-Injecting Patients With Type 2 Diabetes Who Self-monitor Blood Glucose

对使用多次胰岛素注射并进行自我血糖监测的2型糖尿病患者糖尿病管理新兴技术进行综述

期刊:JOURNAL OF PHARMACY TECHNOLOGY
影响因子:1.3
doi:10.1177/8755122518813889
Slugocki, Malgorzata; Bialonczyk, Damian; Özdener, Ayşe Elif
代谢
糖尿病
免疫/内分泌
发表日期：2019
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Reduced Silent Occlusions with a Novel Catheter Infusion Set (BD FlowSmart): Results from Two Open-Label Comparative Studies

新型导管输液装置（BD FlowSmart）可减少无症状性血管阻塞：两项开放标签对比研究的结果

期刊:Diabetes Technology & Therapeutics
影响因子:6.3
doi:10.1089/dia.2015.0342
Gibney, Michael; Xue, Zhenyi; Swinney, Monica; Bialonczyk, Damian; Hirsch, Laurence
发表日期：2016
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