日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cholesterol-conjugated miR-29b induces fetal haemoglobin expression via γ-globin promoter demethylation in the Townes mouse model for sickle cell anaemia

在镰状细胞贫血症的Townes小鼠模型中,胆固醇结合的miR-29b通过γ-珠蛋白启动子去甲基化诱导胎儿血红蛋白表达。

Chithra D Palani ,Alana Smith ,Xueyuan Cao ,Biaoru Li ,Betty S Pace ,Athena Starlard-Davenport

New Generation of Clinical Epigenetics Analysis and Diagnosis for Precision Medicine

新一代临床表观遗传学分析与诊断技术在精准医学中的应用

Song, Pengtao; Li, Biaoru

The histone deacetylase inhibitor CT-101 flips the switch to fetal hemoglobin expression in sickle cell disease mice.

组蛋白去乙酰化酶抑制剂 CT-101 可激活镰状细胞病小鼠体内胎儿血红蛋白的表达

Takezaki Mayuko, Li Biaoru, Xu Hongyan, Patel Nikhil, Lucas Rudolf, Cerbone Ryan E, Koti Sivanagireddy, Hendrick Clifford L, Junker Louis H, Pace Betty S

Editorial: Epigenetics in cancer: mechanisms and drug development-volume II

社论:癌症中的表观遗传学:机制与药物研发——第二卷

Zhu, Xiao; Xu, Zhenhua; Li, Biaoru

Why do tumor-infiltrating lymphocytes have variable efficacy in the treatment of solid tumors?

为什么肿瘤浸润淋巴细胞在治疗实体瘤方面疗效不一?

Li, Biaoru

Salubrinal induces fetal hemoglobin expression via the stress-signaling pathway in human sickle erythroid progenitors and sickle cell disease mice

Salubrinal 通过应激信号通路诱导人类镰状红细胞祖细胞和镰状细胞病小鼠的胎儿血红蛋白表达

Nicole H Lopez, Biaoru Li, Chithra Palani, Umapathy Siddaramappa, Mayuko Takezaki, Hongyan Xu, Wenbo Zhi, Betty S Pace

Editorial: Epigenetics in Cancer: Mechanisms and Drug Development

社论:癌症中的表观遗传学:机制与药物研发

Yuan, Huiqing; Huang, Yongmei; Tao, Susu; Li, Biaoru; Xu, Zhenhua; Qi, Yi; Wu, Binhua; Luo, Hui; Zhu, Xiao

Benserazide racemate and enantiomers induce fetal globin gene expression in vivo: Studies to guide clinical development for beta thalassemia and sickle cell disease

苄丝肼外消旋体和对映体在体内诱导胎儿珠蛋白基因表达:指导β地中海贫血和镰状细胞病临床开发的研究

Betty S Pace, Susan Perrine, Biaoru Li, Levi Makala, Hongyan Xu, Mayuko Takezaki, Roman F Wolf, Amy Wang, Xin Xu, Junfeng Huang, Asaf Alimardanov, Gregory J Tawa, Jose Sangerman, Aidan Faller, Wei Zheng, London Toney, Sharie J Haugabook

MIR29B mediates epigenetic mechanisms of HBG gene activation

MIR29B介导HBG基因激活的表观遗传机制

Athena Starlard-Davenport ,Alana Smith ,Luan Vu ,Biaoru Li ,Betty S Pace

MIR-144-mediated NRF2 gene silencing inhibits fetal hemoglobin expression in sickle cell disease

MIR-144介导的NRF2基因沉默可抑制镰状细胞病中的胎儿血红蛋白表达

Biaoru Li, Xingguo Zhu, Christina M Ward, Athena Starlard-Davenport, Mayuko Takezaki, Amber Berry, Alexander Ward, Caroline Wilder, Cindy Neunert, Abdullah Kutlar, Betty S Pace