日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cryo-EM structures of the MnmE-MnmG complex reveal large conformational changes and provide new insights into the mechanism of tRNA modification

MnmE-MnmG复合物的冷冻电镜结构揭示了其构象的显著变化,并为tRNA修饰机制提供了新的见解。

Maes, Laila; Mares-Mejía, Israel; Martin, Ella; Bickel, David; Claeys, Siemen; Vranken, Wim; Fislage, Marcus; Galicia, Christian; Versées, Wim

Identification of non-charged 7.44 analogs interacting with the NHR2 domain of RUNX1-ETO with improved antiproliferative effect in RUNX-ETO positive cells.

鉴定出与 RUNX1-ETO 的 NHR2 结构域相互作用的非带电 7.44 类似物,在 RUNX-ETO 阳性细胞中具有增强的抗增殖作用

Gopalswamy Mohanraj, Bickel David, Dienstbier Niklas, Tu Jia-Wey, Vogt Melina, Schott-Verdugo Stephan, Bhatia Sanil, Etzkorn Manuel, Gohlke Holger

Effects of Phosphorylation on Protein Backbone Dynamics and Conformational Preferences

磷酸化对蛋白质骨架动力学和构象偏好的影响

Bickel, David; Vranken, Wim

Data-driven probabilistic definition of the low energy conformational states of protein residues

基于数据驱动的蛋白质残基低能构象状态概率定义

Gavalda-Garcia, Jose; Bickel, David; Roca-Martinez, Joel; Raimondi, Daniele; Orlando, Gabriele; Vranken, Wim

Arsenate reductase of Rufibacter tibetensis is a metallophosphoesterase evolved to catalyze redox reactions

西藏鲁菲杆菌的砷酸还原酶是一种金属磷酸酯酶,其进化目的是催化氧化还原反应。

Shen, Jie; Song, Xin-Wei; Bickel, David; Rosen, Barry P; Zhao, Fang-Jie; Messens, Joris; Zhang, Jun

Challenges in describing the conformation and dynamics of proteins with ambiguous behavior

描述具有模糊行为的蛋白质的构象和动力学所面临的挑战

Roca-Martinez, Joel; Lazar, Tamas; Gavalda-Garcia, Jose; Bickel, David; Pancsa, Rita; Dixit, Bhawna; Tzavella, Konstantina; Ramasamy, Pathmanaban; Sanchez-Fornaris, Maite; Grau, Isel; Vranken, Wim F

Muscle uncoupling protein 3 overexpression mimics endurance training and reduces circulating biomarkers of incomplete β-oxidation

肌肉解偶联蛋白3的过表达模拟耐力训练,并降低循环中不完全β-氧化的生物标志物。

Aguer, Céline; Fiehn, Oliver; Seifert, Erin L; Bézaire, Véronic; Meissen, John K; Daniels, Amanda; Scott, Kyle; Renaud, Jean-Marc; Padilla, Marta; Bickel, David R; Dysart, Michael; Adams, Sean H; Harper, Mary-Ellen

Empirical Bayes estimation of posterior probabilities of enrichment: a comparative study of five estimators of the local false discovery rate

基于经验贝叶斯方法的富集后验概率估计:五种局部错误发现率估计量的比较研究

Yang, Zhenyu; Li, Zuojing; Bickel, David R

Validation of differential gene expression algorithms: application comparing fold-change estimation to hypothesis testing

差异基因表达算法的验证:以倍数变化估计与假设检验为例的应用比较

Yanofsky, Corey M; Bickel, David R