日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Predicting homologous recombination deficiency and treatment responses using a computed tomography-based foundation model: a preclinical study

利用基于计算机断层扫描的基础模型预测同源重组缺陷和治疗反应:一项临床前研究

Kuang, Sheng; Schuitmaker, Lesley; Wu, Min; Salahuddin, Zohaib; van der Wiel, Alexander; van de Laak, Jella; Lieuwes, Natasja; Biemans, Rianne; Jung, Jennifer; Yaromina, Ala; Dubois, Ludwig J; Woodruff, Henry C; Lambin, Philippe

Deficiencies in the Fanconi anemia or homologous recombination pathway enhance the antitumor effects of the hypoxia-activated prodrug CP-506

范可尼贫血或同源重组途径的缺陷会增强缺氧激活前药CP-506的抗肿瘤作用。

Schuitmaker, Lesley; van der Wiel, Alexander M A; Lieuwes, Natasja G; Biemans, Rianne; Mutsters, Nikki A M; Jung, Jennifer; Bastos, Victoria Claudino; Sagarra, Èlia Prades; Kuang, Sheng; Setton, Jeremy; Langie, Sabine A S; Kampen, Kim R; Theys, Jan; Yaromina, Ala; Dubois, Ludwig J; Lambin, Philippe

The Effect of Dietary Fiber Compositions on the Therapeutic Outcome of Combined Radio- and Immunotherapy in a Preclinical Cancer Model

膳食纤维组成对临床前癌症模型中联合放疗和免疫疗法疗效的影响

Westheim, Annemarie J F; Dubois, Ludwig J; Prades-Sagarra, Elia; Chan, Jiyang; van der Wiel, Alexander M A; Lieuwes, Natasja G; Biemans, Rianne; Cong, Ying; Houben, Tom; Meesters, Dennis M; Yaromina, Ala; van Dijk, Miriam; van Bergenhenegouwen, Jeroen; van Helvoort, Ardy; Langen, Ramon C J; Penders, John; Shiri-Sverdlov, Ronit; Theys, Jan

Differential regulation of radioadaptation by quercetin between human normal and cancer cells

槲皮素对人类正常细胞和癌细胞放射适应性的差异性调节

Li, Chujie; Li, Xiaojun; Biemans, Rianne; Zhang, Rui; Zhang, Ming; Dubois, Ludwig J

MonoHER selectively enhances the radiotherapy response in p53 wild-type breast cancer via stabilization of p53

MonoHER通过稳定p53选择性地增强p53野生型乳腺癌的放射治疗反应。

Li, Chujie; Li, Xiaojun; Biemans, Rianne; Zhang, Ming; Dubois, Ludwig J

Development of a novel anti-CEACAM5 VHH for SPECT imaging and potential cancer therapy applications.

开发一种新型抗CEACAM5 VHH用于SPECT成像和潜在的癌症治疗应用

Cong Ying, Biemans Rianne, Lieuwes Natasja G, Suijlen Dennis, Lambin Philippe, Dijkgraaf Ingrid, Bauwens Matthias, Yaromina Ala, Dubois Ludwig J

Inter-observer variability of organ contouring for preclinical studies with cone beam Computed Tomography imaging

锥形束计算机断层扫描成像在临床前研究中器官轮廓勾画的观察者间差异

Lappas, Georgios; Staut, Nick; Lieuwes, Natasja G; Biemans, Rianne; Wolfs, Cecile J A; van Hoof, Stefan J; Dubois, Ludwig J; Verhaegen, Frank

'On the Spot' Digital Pathology of Breast Cancer Based on Single-Cell Mass Spectrometry Imaging

基于单细胞质谱成像的乳腺癌“现场”数字病理学

Cuypers, Eva; Claes, Britt S R; Biemans, Rianne; Lieuwes, Natasja G; Glunde, Kristine; Dubois, Ludwig; Heeren, Ron M A

Releasing the brakes of tumor immunity with anti-PD-L1 and pushing its accelerator with L19-IL2 cures poorly immunogenic tumors when combined with radiotherapy

利用抗PD-L1抗体解除肿瘤免疫的抑制,并利用L19-IL2抗体加速肿瘤免疫反应,联合放射疗法可治愈免疫原性较差的肿瘤。

Olivo Pimentel, Veronica; Marcus, Damiënne; van der Wiel, Alexander Ma; Lieuwes, Natasja G; Biemans, Rianne; Lieverse, Relinde Iy; Neri, Dario; Theys, Jan; Yaromina, Ala; Dubois, Ludwig J; Lambin, Philippe

E. coli nitroreductase NfsA is a reporter gene for non-invasive PET imaging in cancer gene therapy applications

大肠杆菌硝基还原酶NfsA是一种用于癌症基因治疗应用中非侵入性PET成像的报告基因。

Mowday, Alexandra Marie; Copp, Janine Naomi; Syddall, Sophie Philippa; Dubois, Ludwig Jerome; Wang, Jingli; Lieuwes, Natasja Gabi; Biemans, Rianne; Ashoorzadeh, Amir; Abbattista, Maria Rosaria; Williams, Elsie May; Guise, Christopher Paul; Lambin, Philippe; Ackerley, David Francis; Smaill, Jeff Bruce; Theys, Jan; Patterson, Adam Vorn