日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Inhibition of dimeric SARS-CoV-2 Mpro displays positive cooperativity and a mixture of covalent and non-covalent binding.

二聚体 SARS-CoV-2 Mpro 的抑制表现出正协同性，并且是共价和非共价结合的混合

期刊:iScience
影响因子:4.1
doi:10.1016/j.isci.2025.112773
Padmanabha Das Krishna M, Chen Jun, Charifson Paul S, Green Jeremy, Tang Henry, Panchal Sanjay, Pu Fan, Korepanova Alla, Dubey Abhinav, Afanador Gustavo, Stojkovic Vladimir, Nocek Boguslaw, Bigelow Lance, Stubbs Sarah H, Davey Robert A, DeGoey David A, Arthanari Haribabu, Namchuk Mark N
炎症/感染
新冠
发表日期：2025
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3D domain swapping in the TIM barrel of the α subunit of Streptococcus pneumoniae tryptophan synthase

肺炎链球菌色氨酸合成酶α亚基TIM桶状结构中的3D结构域交换

期刊:Acta Crystallographica Section D-Structural Biology
影响因子:3.8
doi:10.1107/S2059798320000212
Michalska, Karolina; Kowiel, Marcin; Bigelow, Lance; Endres, Michael; Gilski, Miroslaw; Jaskolski, Mariusz; Joachimiak, Andrzej
肺炎
3D/类器官
TIM
发表日期：2020
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Conservation of the structure and function of bacterial tryptophan synthases

细菌色氨酸合成酶结构和功能的保守性

期刊:IUCrJ
影响因子:3.6
doi:10.1107/S2052252519005955
Michalska, Karolina; Gale, Jennifer; Joachimiak, Grazyna; Chang, Changsoo; Hatzos-Skintges, Catherine; Nocek, Boguslaw; Johnston, Stephen E; Bigelow, Lance; Bajrami, Besnik; Jedrzejczak, Robert P; Wellington, Samantha; Hung, Deborah T; Nag, Partha P; Fisher, Stewart L; Endres, Michael; Joachimiak, Andrzej
微生物学
发表日期：2019
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Brucella Periplasmic Protein EipB Is a Molecular Determinant of Cell Envelope Integrity and Virulence

布鲁氏菌周质蛋白EipB是细胞包膜完整性和毒力的分子决定因素

期刊:Journal of Bacteriology
影响因子:3
doi:10.1128/JB.00134-19
Herrou, Julien; Willett, Jonathan W; Fiebig, Aretha; Czyż, Daniel M; Cheng, Jason X; Ultee, Eveline; Briegel, Ariane; Bigelow, Lance; Babnigg, Gyorgy; Kim, Youngchang; Crosson, Sean
细胞生物学
发表日期：2019
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Structural Insights into the Free-Standing Condensation Enzyme SgcC5 Catalyzing Ester-Bond Formation in the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027

对催化烯二炔类抗肿瘤抗生素C-1027生物合成中酯键形成的独立缩合酶SgcC5的结构解析

期刊:Biochemistry
影响因子:3
doi:10.1021/acs.biochem.8b00174
Chang, Chin-Yuan; Lohman, Jeremy R; Huang, Tingting; Michalska, Karolina; Bigelow, Lance; Rudolf, Jeffrey D; Jedrzejczak, Robert; Yan, Xiaohui; Ma, Ming; Babnigg, Gyorgy; Joachimiak, Andrzej; Phillips, George N Jr; Shen, Ben
肿瘤
肿瘤免疫
发表日期：2018
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Crystal Structure of Thioesterase SgcE10 Supporting Common Polyene Intermediates in 9- and 10-Membered Enediyne Core Biosynthesis

硫酯酶 SgcE10 的晶体结构支持 9 元和 10 元烯二炔核心生物合成中常见的多烯中间体。

期刊:ACS Omega
影响因子:4.3
doi:10.1021/acsomega.7b00933
Annaval, Thibault; Rudolf, Jeffrey D; Chang, Chin-Yuan; Lohman, Jeremy R; Kim, Youngchang; Bigelow, Lance; Jedrzejczak, Robert; Babnigg, Gyorgy; Joachimiak, Andrzej; Phillips, George N Jr; Shen, Ben
发表日期：2017
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Crystal structure of SgcJ, an NTF2-like superfamily protein involved in biosynthesis of the nine-membered enediyne antitumor antibiotic C-1027

SgcJ 的晶体结构，SgcJ 是一种 NTF2 样超家族蛋白，参与九元烯二炔抗肿瘤抗生素 C-1027 的生物合成。

期刊:Journal of Antibiotics
影响因子:2.7
doi:10.1038/ja.2016.88
Huang, Tingting; Chang, Chin-Yuan; Lohman, Jeremy R; Rudolf, Jeffrey D; Kim, Youngchang; Chang, Changsoo; Yang, Dong; Ma, Ming; Yan, Xiaohui; Crnovcic, Ivana; Bigelow, Lance; Clancy, Shonda; Bingman, Craig A; Yennamalli, Ragothaman M; Babnigg, Gyorgy; Joachimiak, Andrzej; Phillips, George N; Shen, Ben
肿瘤
肿瘤免疫
NTF2
发表日期：2016
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Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases

“无AT”型I型聚酮合酶酮合成酶的结构和进化关系

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.1515460112
Lohman, Jeremy R; Ma, Ming; Osipiuk, Jerzy; Nocek, Boguslaw; Kim, Youngchang; Chang, Changsoo; Cuff, Marianne; Mack, Jamey; Bigelow, Lance; Li, Hui; Endres, Michael; Babnigg, Gyorgy; Joachimiak, Andrzej; Phillips, George N Jr; Shen, Ben
发表日期：2015
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Structural characterization of AtmS13, a putative sugar aminotransferase involved in indolocarbazole AT2433 aminopentose biosynthesis

AtmS13的结构表征，AtmS13是一种推测的糖氨基转移酶，参与吲哚咔唑AT2433氨基戊糖的生物合成。

期刊:Proteins-Structure Function and Bioinformatics
影响因子:2.8
doi:10.1002/prot.24844
Singh, Shanteri; Kim, Youngchang; Wang, Fengbin; Bigelow, Lance; Endres, Michael; Kharel, Madan K; Babnigg, Gyorgy; Bingman, Craig A; Joachimiak, Andrzej; Thorson, Jon S; Phillips, George N Jr
发表日期：2015
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The crystal structure of BlmI as a model for nonribosomal peptide synthetase peptidyl carrier proteins

BlmI晶体结构作为非核糖体肽合成酶肽基载体蛋白的模型

期刊:Proteins-Structure Function and Bioinformatics
影响因子:2.8
doi:10.1002/prot.24485
Lohman, Jeremy R; Ma, Ming; Cuff, Marianne E; Bigelow, Lance; Bearden, Jessica; Babnigg, Gyorgy; Joachimiak, Andrzej; Phillips, George N Jr; Shen, Ben
发表日期：2014
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