日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Investigating predictors of pain events during trials of knee osteoarthritis: A post-hoc analysis of two phase III trials

探究膝骨关节炎临床试验中疼痛事件的预测因素:两项 III 期临床试验的事后分析

Kaaber, Andrea Bak; Bentin, Jakob Mejdahl; Adrian, Ida Sofie; Karsdal, Morten Asser; Bihlet, Asger Reinstrup

Weight loss ameliorates symptoms of osteoarthritis and is correlated with alterations in soluble bone and cartilage markers: an analysis of patient-reported outcomes and biomarkers

减肥可改善骨关节炎症状,并与可溶性骨和软骨标志物的变化相关:一项基于患者报告结果和生物标志物的分析

Bay-Jensen, Anne-Christine; Mohamed, Khaled; Frederiksen, Peder; Bihlet, Asger; Thudium, Christian; Henriksen, Kim; Karsdal, Morten

The Impact of Weight-bearing Exercise, Non-Weight-bearing Exercise, and Cardiovascular Stress on Biochemical Markers of Cartilage Turnover in Patients With Mild to Moderate Knee Osteoarthritis - A Sequential, Cross-Over, Clinical Study

负重运动、非负重运动和心血管应激对轻中度膝骨关节炎患者软骨代谢生化标志物的影响——一项序贯交叉临床研究

Bjerre-Bastos, Jonathan J; Sejersen, Casper; Nielsen, Henning Bay; Boesen, Mikael; Secher, Niels H; Distajo, Gregorio; Flood, Vincent; Henrotin, Yves; Uebelhoer, Melanie; Krustrup, Peter; Kitchen, Carl-Christian; Thudium, Christian S; Andersen, Jeppe R; Bihlet, Asger R

Safety, Tolerability, and Pharmacodynamics of the ADAMTS-5 Nanobody M6495: Two Phase 1, Single-Center, Double-Blind, Randomized, Placebo-Controlled Studies in Healthy Subjects and Patients With Osteoarthritis

ADAMTS-5纳米抗体M6495的安全性、耐受性和药效学:两项在健康受试者和骨关节炎患者中进行的I期单中心双盲随机安慰剂对照研究

Bihlet, Asger Reinstrup; Balchen, Torben; Goteti, Kosalaram; Sonne, Jesper; Ladel, Christoph; Karsdal, Morten Asser; Ona, Victor; Moreau, Flavie; Waterhouse, Roseann; Bay-Jensen, Anne-Christine; Guehring, Hans

Unbiased analysis of knee cartilage thickness change over three years after sprifermin vs. placebo treatment - A post-hoc analysis from the phase 2B FORWARD study

对接受 sprifermin 治疗与安慰剂治疗三年后膝关节软骨厚度变化的无偏分析——来自 2B 期 FORWARD 研究的事后分析

Eckstein, Felix; Maschek, Susanne; Wirth, Wolfgang; Ladel, Christoph; Bihlet, Asger Reinstrup; Knight, Chris; Somberg, Kenneth; Zhao, Luping

Reflections from the OARSI 2022 clinical trials symposium: The pain of OA-Deconstruction of pain and patient-reported outcome measures for the benefit of patients and clinical trial design

来自 OARSI 2022 临床试验研讨会的反思:骨关节炎的疼痛——为了患者和临床试验设计的利益,对疼痛和患者报告结局指标进行解构

Karsdal, M A; Tambiah, J; Felson, D; Ladel, C; Nikolov, N P; Hodgins, D; Bihlet, A R; Neogi, T; Baatenburg de Jong, C; Bay-Jensen, A C; Baron, R; Laslop, A; Mobasheri, A; Kraus, V B

Joint biomarker response to mechanical stimuli in osteoarthritis - A scoping review

骨关节炎中关节生物标志物对机械刺激的反应——一项范围界定综述

Bjerre-Bastos, Jonathan J; Hamrouni, Nizar; Henrotin, Yves; Thudium, Christian S; Bihlet, Asger R

Associations between single-question Visual Analogue Scale pain score and weight-bearing and non-weight-bearing domains of Western Ontario and McMaster Universities Arthritis Index pain: data from 2 phase 3 clinical trials

单项视觉模拟评分法疼痛评分与西安大略大学和麦克马斯特大学关节炎指数(WOMAC)的负重和非负重疼痛领域之间的关联:来自两项3期临床试验的数据

Bjerre-Bastos, Jonathan J; Miller, Claire P; Li, Yanqi; Andersen, Jeppe R; Karsdal, Morten; Bihlet, Asger R

Effect of adrenaline on serum mid-regional pro-atrial natriuretic peptide and central blood volume

肾上腺素对血清中段前脑钠肽和中心血容量的影响

Sejersen, Casper; Bjerre-Bastos, Jonathan J; Goetze, Jens P; Nielsen, Henning B; Bihlet, Asger R; Secher, Niels H

Long-term structural and symptomatic effects of intra-articular sprifermin in patients with knee osteoarthritis: 5-year results from the FORWARD study

关节内注射司普利福明对膝骨关节炎患者的长期结构和症状影响:FORWARD 研究的 5 年结果

Eckstein, Felix; Hochberg, Marc C; Guehring, Hans; Moreau, Flavie; Ona, Victor; Bihlet, Asger Reinstrup; Byrjalsen, Inger; Andersen, Jeppe Ragnar; Daelken, Benjamin; Guenther, Oliver; Ladel, Christoph; Michaelis, Martin; Conaghan, Philip G