日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Incomplete lytic cycle of a widespread Bacteroides bacteriophage leads to the formation of defective viral particles.

广泛存在的拟杆菌噬菌体裂解周期不完全,导致缺陷病毒颗粒的形成

Vendrell-Fernández Sol, Beamud Beatriz, Abou Haydar Yasmina, Am de Sousa Jorge, Burlaud-Gaillard Julien, Kornobis Etienne, Raynal Bertrand, Vinh Joelle, Bikard David, Ghigo Jean-Marc

Antibiotics and phages drive region-specific diversity of OmpK36 in Klebsiella pneumoniae

抗生素和噬菌体驱动肺炎克雷伯菌中 OmpK36 的区域特异性多样性

Royer, Guilhem; Laurenceau, Raphaël; Cabanel, Nicolas; Bardiaux, Benjamin; Cerdas-Mejías, Karol Melissa; Bikard, David; Rosinski-Chupin, Isabelle; Glaser, Philippe

Specificity and mechanism of tRNA cleavage by the AriB Toprim nuclease of the PARIS bacterial immune system.

PARIS 细菌免疫系统的 AriB Toprim 核酸酶对 tRNA 的切割特异性和机制

Belukhina Svetlana, Saudemont Baptiste, Depardieu Florence, Lorthios Tom, P Maviza Tinashe, Livenskyi Alexei, Serebryakova Marina, Aleksandrova Maria, Ukholkina Elizaveta, Burmistrova Nadezhda, Sergiev Petr, Libiad Marouane, Dubrac Sarah, Barras Frederic, Motorin Yuri, Marchand Virginie, Hagelueken Gregor, Isaev Artem, Bikard David, Rouillon Christophe

Author Correction: A virally encoded tRNA neutralizes the PARIS antiviral defence system

作者更正:病毒编码的tRNA能够中和PARIS抗病毒防御系统。

Burman, Nathaniel; Belukhina, Svetlana; Depardieu, Florence; Wilkinson, Royce A; Skutel, Mikhail; Santiago-Frangos, Andrew; Graham, Ava B; Livenskyi, Alexei; Chechenina, Anna; Morozova, Natalia; Zahl, Trevor; Henriques, William S; Buyukyoruk, Murat; Rouillon, Christophe; Saudemont, Baptiste; Shyrokova, Lena; Kurata, Tatsuaki; Hauryliuk, Vasili; Severinov, Konstantin; Groseille, Justine; Thierry, Agnès; Koszul, Romain; Tesson, Florian; Bernheim, Aude; Bikard, David; Wiedenheft, Blake; Isaev, Artem

Cassette recombination dynamics within chromosomal integrons are regulated by toxin-antitoxin systems

染色体整合子内的盒式重组动力学受毒素-抗毒素系统的调控。

Richard, Egill; Darracq, Baptiste; Littner, Eloi; Vit, Claire; Whiteway, Clémence; Bos, Julia; Fournes, Florian; Garriss, Geneviève; Conte, Valentin; Lapaillerie, Delphine; Parissi, Vincent; Rousset, François; Skovgaard, Ole; Bikard, David; Rocha, Eduardo P C; Mazel, Didier; Loot, Céline

Delivery of functional Cas:DNA nucleoprotein complexes into recipient bacteria through a type IV secretion system

通过IV型分泌系统将功能性Cas:DNA核蛋白复合物递送至受体细菌。

Guzmán-Herrador, Dolores L; Fernández-Gómez, Andrea; Depardieu, Florence; Bikard, David; Llosa, Matxalen

Generation of a Biotin-Tagged Dual-Display Phage

生物素标记双展示噬菌体的构建

De Plano, Laura Maria; Oddo, Salvatore; Bikard, David; Caccamo, Antonella; Conoci, Sabrina

Cas9 off-target binding to the promoter of bacterial genes leads to silencing and toxicity

Cas9 与细菌基因启动子的非靶向结合会导致基因沉默和毒性。

Rostain, William; Grebert, Theophile; Vyhovskyi, Danylo; Pizarro, Paula Thiel; Tshinsele-Van Bellingen, Gatwa; Cui, Lun; Bikard, David

Computational design of novel Cas9 PAM-interacting domains using evolution-based modelling and structural quality assessment

利用基于进化的建模和结构质量评估进行新型Cas9 PAM相互作用域的计算设计

Malbranke, Cyril; Rostain, William; Depardieu, Florence; Cocco, Simona; Monasson, Rémi; Bikard, David

Microbial defenses against mobile genetic elements and viruses: Who defends whom from what?

微生物对移动遗传元件和病毒的防御机制:谁在保护谁免受什么侵害?

Rocha, Eduardo P C; Bikard, David