日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Mesoporous Silica Nanoparticles-Based Formulations for Enhanced Oral Delivery of Peptide Drugs: A Case Study on Insulin

基于介孔二氧化硅纳米颗粒的制剂增强肽类药物的口服递送：以胰岛素为例

期刊:Small
影响因子:12.1
doi:10.1002/smll.202513347
Iriarte-Mesa, Claudia; Juère, Estelle; Bileck, Andrea; Kremsmayr, Thomas; Goodson, Michael L; Ehrlich, Allison; Hodžić, Adnan; Kunert, Martin; Gerner, Christopher; Kählig, Hanspeter; Marko, Doris; Muttenthaler, Markus; Berry, David; Del Favero, Giorgia; Kleitz, Freddy
免疫/内分泌
发表日期：2026
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Structure-Activity Relationships of Silver(I)- and Gold(I)-NHC Complexes Reveal Distinctly Different Responses of Cisplatin-Resistant Ovarian Cancer to Bis-NHC-Gold(I) Derivatives

银(I)-和金(I)-NHC配合物的构效关系揭示了顺铂耐药卵巢癌对双-NHC-金(I)衍生物的截然不同的反应

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.5c02355
Bormio Nunes, Julia H; Hacker, Christina; Caban, Monika; Valcanover, Daniel; Yassemipour, Patrick A; Türck, Sebastian; Ott, Ingo; Skos, Lukas; Bileck, Andrea; Gerner, Christopher; Meier-Menches, Samuel M; Mohr, Thomas; Berger, Walter; Kowol, Christian R; Heffeter, Petra
肿瘤
肿瘤免疫
卵巢癌
发表日期：2026
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Beyond the stop: Oxadiazole TRIDs restore LRBA protein expression in nonsense-driven primary immunodeficiency

超越终点：恶二唑类TRIDs可恢复无义突变驱动的原发性免疫缺陷中的LRBA蛋白表达

期刊:Molecular Therapy-Nucleic Acids
影响因子:6.1
doi:10.1016/j.omtn.2025.102808
Fiduccia, Ignazio; Vitale, Emanuele; Varrica, Riccardo; Ricci, Davide; Marino, Sefora; Zito, Antonino; Pace, Andrea; Colige, Alain; Moutschen, Michel; Borutzki, Yasmin; Bileck, Andrea; Meier-Menches, Samuel M; Lentini, Laura; Pibiri, Ivana
免疫/内分泌
发表日期：2026
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A Gold-PROTAC Degrades the Oncogenic Tyrosine Kinase MERTK: Insights into the Degradome from a Steady-State System

金-PROTAC降解致癌酪氨酸激酶MERTK：来自稳态系统的降解组学见解

期刊:ACS Chemical Biology
影响因子:3.8
doi:10.1021/acschembio.5c00860
Thomas, Sophie R; Iellici, Thomas; Park, Mihyun; Klaus, Elisabeth; Bileck, Andrea; Gerner, Christopher; Meier-Menches, Samuel M; Casini, Angela
信号转导
肿瘤
MERTK
肿瘤免疫
发表日期：2026
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Selectivity for TP53 signalling drives the mode of action of a highly potent N,O,O-tridentate naphthoquinone-based organo-ruthenium anticancer drug candidate

一种高效的基于N,O,O-三齿萘醌的有机钌抗癌候选药物的作用机制取决于其对TP53信号通路的选择性。

期刊:Chemical Science
影响因子:7.4
doi:10.1039/d5sc00735f
Rosner, Alexander; Skos, Lukas; Mendrina, Theresa; Baier, Dina; Hejl, Michaela; Borutzki, Yasmin; Gradl, Mathias; Geisler, Heiko; Mohr, Thomas; Legin, Anton; Jakupec, Michael A; Bileck, Andrea; Gerner, Christopher; Koellensperger, Gunda; Heffeter, Petra; Berger, Walter; Keppler, Bernhard K; Kandioller, Wolfgang; Meier-Menches, Samuel M
信号转导
肿瘤
P53
肿瘤免疫
发表日期：2025
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Time Course of Plasma Proteomic and Oxylipin Changes Induced by LPS Challenge and Modulated by Antioxidant Supplementation in a Randomized Controlled Trial

随机对照试验中LPS刺激诱导的血浆蛋白质组学和氧化脂质变化的时间进程及抗氧化剂补充的调节作用

期刊:Antioxidants
影响因子:6.6
doi:10.3390/antiox14050536
Hagn, Gerhard; Bileck, Andrea; Mohr, Thomas; Schmidl, Doreen; Baron, David M; Jilma, Bernd; Schmetterer, Leopold; Garhöfer, Gerhard; Gerner, Christopher
氧化脂质
发表日期：2025
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Plectin-mediated cytoskeletal crosstalk as a target for inhibition of hepatocellular carcinoma growth and metastasis

以 Plectin 介导的细胞骨架串扰为靶点抑制肝细胞癌的生长和转移

期刊:Elife
影响因子:6.4
doi:10.7554/eLife.102205
Outla, Zuzana; Oyman-Eyrilmez, Gizem; Korelova, Katerina; Prechova, Magdalena; Frick, Lukas; Sarnova, Lenka; Bisht, Piyush; Novotna, Petra; Kosla, Jan; Bortel, Patricia; Borutzki, Yasmin; Bileck, Andrea; Gerner, Christopher; Rahbari, Mohammad; Rahbari, Nuh; Birgin, Emrullah; Kvasnicova, Bibiana; Galisova, Andrea; Sulkova, Katerina; Bauer, Andreas; Jobe, Njainday; Tolde, Ondrej; Sticova, Eva; Rösel, Daniel; O'Connor, Tracy; Otahal, Martin; Jirak, Daniel; Heikenwälder, Mathias; Wiche, Gerhard; Meier-Menches, Samuel M; Gregor, Martin
细胞生物学
肿瘤
肿瘤免疫
发表日期：2025
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Retrograde rearrangement of mitochondria correlates with nuclear deformation and genotoxic damage.

线粒体逆行重排与核变形和基因毒性损伤相关

期刊:iScience
影响因子:4.1
doi:10.1016/j.isci.2025.112955
Jobst Maximilian, Crudo Francesco, Marko Doris, Bileck Andrea, Meier-Menches Samuel Matthias, Gerner Christopher, Del Favero Giorgia
毒理研究
线粒体
发表日期：2025
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Dexamethasone: a double-edged sword in the treatment of osteoarthritis

地塞米松：治疗骨关节炎的双刃剑

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-025-96050-2
Tarasova, Karyna; Arteaga, Maria Belen; Kidtiwong, Angkana; Gueltekin, Sinan; Bileck, Andrea; Gerner, Christopher; Gerner, Iris; Jenner, Florien
关节炎
发表日期：2025
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Proteomic Analysis of FFPE Tissue Samples Identifies Potential Molecular Mechanisms Mediating Resistance to Radiotherapy in Rectal Cancer

对FFPE组织样本的蛋白质组学分析揭示了直肠癌放射治疗耐药的潜在分子机制

期刊:Journal of Proteome Research
影响因子:3.6
doi:10.1021/acs.jproteome.5c00114
Zott, Tobias; Wolf, Michael; Plessl-Walder, Günter; Regele, Heinz; Bergmann, Michael; Meier-Menches, Samuel M; Gerner, Christopher; Silberhumer, Gerd R; Bileck, Andrea
肿瘤
肠癌
肿瘤免疫
治疗耐药
发表日期：2025
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