日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

1'- and 4'-Cyano Modified Adenosine Analogs Against Prototypic Flavivirus RNA-Dependent RNA Polymerases

1'-和4'-氰基修饰的腺苷类似物对抗原型黄病毒RNA依赖性RNA聚合酶

Walker, Simon M; Gordon, Calvin J; Tchesnokov, Egor P; Sun, Long; Zou, Jing; Xie, Xuping; Riola, Nicholas C; Cutillas, Vincent; Du Pont, Venice; Zhao, Xiaofeng; Wang, Ting; Pitts, Jared; Siegel, Dustin S; Perry, Jason K; Feng, Joy Y; Bilello, John P; Götte, Matthias

Antiviral Activity of Remdesivir and Obeldesivir Against SARS-CoV-2 Omicron Subvariants That Were Circulating from September 2023 Through June 2025

瑞德西韦和奥贝德西韦对2023年9月至2025年6月期间流行的SARS-CoV-2 Omicron亚型的抗病毒活性

Rodriguez, Lauren; Li, Jiani; Han, Dong; Peinovich, Nadine; Martinez, Clarissa; Ho, Pui Yan; Zamora, J Lizbeth Reyes; Martin, Ross; Bilello, John P; Perry, Jason K; Hedskog, Charlotte

A structural roadmap for the formation of the coronavirus nsp3/nsp4 double membrane vesicle pore and its implications for polyprotein processing and replication/transcription

冠状病毒nsp3/nsp4双膜囊泡孔形成的结构路线图及其对多聚蛋白加工和复制/转录的影响

Perry, Jason K; Itskanov, Samuel; Bilello, John P; Lansdon, Eric B

Remdesivir and Obeldesivir Retain Potent Antiviral Activity Against SARS-CoV-2 Omicron Variants

瑞德西韦和奥贝德西韦对SARS-CoV-2 Omicron变异株仍具有强效抗病毒活性

Rodriguez, Lauren; Zamora, J Lizbeth Reyes; Han, Dong; Moshiri, Jasmine; Peinovich, Nadine; Martinez, Clarissa; Ho, Pui Yan; Li, Jiani; Aeschbacher, Thomas; Martin, Ross; Pekosz, Andrew; Bilello, John P; Perry, Jason K; Hedskog, Charlotte

Template switching by coronavirus polymerase requires helicase activity and is stimulated by remdesivir and molnupiravir

冠状病毒聚合酶的模板转换需要解旋酶活性,并可被瑞德西韦和莫努皮韦刺激。

Rakib, Asif; Das, Arnab; Bera, Subhas C; America, Pim P B; Klein, Misha; Anderson, Thomas K; Marecki, John C; Wang, Bing; Bogers, Eline; Feng, Joy Y; Bilello, John P; Papini, Flávia S; Smitskamp, Quinte; Arnold, Jamie J; Artsimovitch, Irina; Kirchdoerfer, Robert N; Cameron, Craig E; Raney, Kevin D; Dulin, David

Meeting report of the 37th International Conference on Antiviral Research in Gold Coast, Australia, May 20-24, 2024, organized by the International Society for Antiviral Research

第37届国际抗病毒研究大会会议报告,2024年5月20日至24日,澳大利亚黄金海岸,由国际抗病毒研究学会主办

Welch, Stephen R; Bilello, John P; Carter, Kara; Delang, Leen; Dirr, Larissa; Durantel, David; Feng, Joy Y; Gowen, Brian B; Herrero, Lara J; Janeba, Zlatko; Kleymann, Gerald; Lee, Alpha A; Meier, Chris; Moffat, Jennifer; Schang, Luis M; Schiffer, Joshua T; Seley-Radtke, Katherine L; Sheahan, Timothy P; Spengler, Jessica R

Efficacy of the oral nucleoside prodrug GS-5245 (Obeldesivir) against SARS-CoV-2 and coronaviruses with pandemic potential

口服核苷前药GS-5245(奥贝地西韦)对SARS-CoV-2和具有大流行潜力的冠状病毒的疗效

Martinez, David R; Moreira, Fernando R; Zweigart, Mark R; Gully, Kendra L; De la Cruz, Gabriela; Brown, Ariane J; Adams, Lily E; Catanzaro, Nicholas; Yount, Boyd; Baric, Thomas J; Mallory, Michael L; Conrad, Helen; May, Samantha R; Dong, Stephanie; Scobey, D Trevor; Montgomery, Stephanie A; Perry, Jason; Babusis, Darius; Barrett, Kimberly T; Nguyen, Anh-Hoa; Nguyen, Anh-Quan; Kalla, Rao; Bannister, Roy; Bilello, John P; Feng, Joy Y; Cihlar, Tomas; Baric, Ralph S; Mackman, Richard L; Schäfer, Alexandra; Sheahan, Timothy P

An atomistic model of the coronavirus replication-transcription complex as a hexamer assembled around nsp15

冠状病毒复制转录复合物的原子模型,该复合物是由nsp15组装而成的六聚体。

Perry, Jason K; Appleby, Todd C; Bilello, John P; Feng, Joy Y; Schmitz, Uli; Campbell, Elizabeth A

Vaccine protection against simian immunodeficiency virus in monkeys using recombinant gamma-2 herpesvirus.

利用重组γ-2疱疹病毒对猴子进行抗猴免疫缺陷病毒的疫苗保护

Bilello John P, Manrique Julieta M, Shin Young C, Lauer William, Li Wenjun, Lifson Jeffrey D, Mansfield Keith G, Johnson R Paul, Desrosiers Ronald C

Infection and persistence of rhesus monkey rhadinovirus in immortalized B-cell lines

恒河猴疱疹病毒在永生化B细胞系中的感染和持续存在

Bilello, John P; Lang, Sabine M; Wang, Fred; Aster, Jon C; Desrosiers, Ronald C