日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Heterozygous ADAR mutant mice exhibit RNA sensing-dependent neuroinflammation and phenotypes associated with Aicardi-Goutières syndrome

杂合子ADAR突变小鼠表现出RNA感知依赖性神经炎症以及与艾卡迪-古蒂埃综合征相关的表型。

期刊:iScience
影响因子:4.1
doi:10.1016/j.isci.2026.114758
Guo, Xinfeng; Liu, Jia-Jun; Shang, Chaowei; Guerriero, Christopher J; Wiley, Clayton; Steinman, Richard A; Sheng, Yi; Billiar, Timothy R; Schwartz, Daniella M; Brodsky, Jeffrey L; Liu, Silvia; Wang, Qingde
炎症
炎症/感染
神经科学
神经炎症
ADA
发表日期：2026
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Author Correction: PKM2-dependent glycolysis promotes NLRP3 and AIM2 inflammasome activation

作者更正：PKM2依赖性糖酵解促进NLRP3和AIM2炎症小体的激活。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-60997-7
Xie, Min; Yu, Yan; Kang, Rui; Zhu, Shan; Yang, Liangchun; Zeng, Ling; Sun, Xiaofang; Yang, Minghua; Billiar, Timothy R; Wang, Haichao; Cao, Lizhi; Jiang, Jianxin; Tang, Daolin
炎症
炎性小体
炎症/感染
AIM2
LRP3
NLRP3
炎性小体
免疫/内分泌
发表日期：2025
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Myeloperoxidase-anchored ENO1 mediates neutrophil extracellular trap DNA to enhance Treg differentiation via IFITM2 during sepsis

髓过氧化物酶锚定的ENO1介导中性粒细胞胞外陷阱DNA，通过IFITM2增强脓毒症期间Treg细胞的分化。

期刊:Journal of Clinical Investigation
影响因子:13.6
doi:10.1172/JCI183541
Jiang, Yi; Gao, Shenjia; Li, Xiya; Sun, Hao; Wu, Xinyi; Gu, Jiahui; Chen, Zhaoyuan; Wu, Han; Zhao, Xiaoqiang; Zhang, Tongtong; Ben-Ami, Ronen; Le, Yuan; Billiar, Timothy R; Miao, Changhong; Zhang, Jie; Wang, Jun; Chen, Wankun
T细胞
中性粒细胞
炎症/感染
败血症
粒细胞
Treg
细胞生物学
发表日期：2025
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A neuroimmune pathway drives bacterial infection.

神经免疫通路驱动细菌感染

期刊:Science Advances
影响因子:12.5
doi:10.1126/sciadv.adr2226
Wang Nian, Liu Jiao, Wu Runliu, Chen Feng, Zhang Ruoxi, Yu Chunhua, Zeh Herbert, Xiao Xianzhong, Wang Haichao, Billiar Timothy R, Zeng Ling, Jiang Jianxin, Tang Daolin, Kang Rui
神经科学
发表日期：2025
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High-dimensional analysis of injured patients reveals distinct circulating proteomic profiles in plasma vs. whole blood resuscitation

对受伤患者的高维分析揭示了血浆与全血复苏液中不同的循环蛋白质组学特征

期刊:Cell Reports Medicine
影响因子:10.6
doi:10.1016/j.xcrm.2025.102022
Moheimani, Hamed; Sun, Xuejing; Ozel, Mehves; Darby, Jennifer L; Ong, Erika P; Oyebamiji, Tunde; Kar, Upendra K; Yazer, Mark H; Neal, Matthew D; Guyette, Francis X; Wisniewski, Stephen R; Cotton, Bryan A; Cannon, Jeremy W; Schreiber, Martin A; Moore, Ernest E; Namias, Nicholas; Minei, Joseph P; Barrett, Christopher D; Das, Jishnu; Sperry, Jason L; Billiar, Timothy R
发表日期：2025
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Correction: Plumbagin protects mice from lethal Sepsis by modulating immunometabolism upstream of PKM2

更正：Plumbagin 通过调节 PKM2 上游的免疫代谢来保护小鼠免受致命性脓毒症的侵害。

期刊:Molecular Medicine
影响因子:6.4
doi:10.1186/s10020-025-01329-9
Zhang, Zhaoxia; Deng, Wenjun; Kang, Rui; Xie, Min; Billiar, Timothy; Wang, Haichao; Cao, Lizhi; Tang, Daolin
炎症/感染
败血症
代谢
免疫代谢
免疫/内分泌
发表日期：2025
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Elevated tumor NOS2/COX2 promotes immunosuppressive phenotypes associated with poor survival in ER- breast cancer

肿瘤NOS2/COX2水平升高会促进与ER阴性乳腺癌患者预后不良相关的免疫抑制表型。

期刊:JCI Insight
影响因子:6.1
doi:10.1172/jci.insight.193091
Ridnour, Lisa A; Cheng, Robert Ys; Heinz, William F; Pore, Milind; Gonzalez, Ana L; Femino, Elise L; Moffat, Rebecca L; Wink, Adelaide L; Imtiaz, Fatima; Coutinho, Leandro L; Butcher, Donna; Edmondson, Elijah F; Rangel, M Cristina; Wong, Stephen Tc; Lipkowitz, Stanley; Glynn, Sharon A; Vitek, Michael P; McVicar, Daniel W; Li, Xiaoxian; Anderson, Stephen K; Paolocci, Nazareno; Hewitt, Stephen M; Ambs, Stefan; Billiar, Timothy R; Chang, Jenny C; Lockett, Stephen J; Wink, David A
COX2
肿瘤
肿瘤免疫
乳腺癌
免疫/内分泌
发表日期：2025
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Single-cell transcriptomic analysis identified resistant MDSCs and a stress-tolerant gene co-expression network as common MDSC features across multiple disease settings

单细胞转录组分析发现，耐药性髓源性抑制细胞（MDSC）和应激耐受基因共表达网络是多种疾病环境下MDSC的共同特征。

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2025.1565211
Chen, Tianmeng; Hughes, Julia; Gregory, Alyssa; Conroy, Julia; Loughran, Patricia; Song, Jinming; Chen, Wei; Billiar, Timothy
MDSC
细胞生物学
单细胞
发表日期：2025
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Value of animal sepsis research in navigating the translational labyrinth

动物脓毒症研究在转化医学迷宫中的价值

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2025.1593342
Wang, Haichao; Ayala, Alfred; Aziz, Monowar; Billiar, Timothy R; Deutschman, Clifford S; Jeyaseelan, Samithamby; Tang, Daolin; Wang, Ping
炎症/感染
败血症
发表日期：2025
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Nondestructive Mechanical Characterization of Bioengineered Tissues by Digital Holography

利用数字全息技术对生物工程组织进行无损力学表征

期刊:ACS Biomaterials Science & Engineering
影响因子:5.5
doi:10.1021/acsbiomaterials.4c01503
Hiscox, Colin; Li, Juanyong; Gao, Ziyang; Korkin, Dmitry; Furlong, Cosme; Billiar, Kristen
发表日期：2025
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