Dual inhibition of the TrkA and JAK2 pathways using entrectinib and pacritinib suppresses the growth and metastasis of HER2-positive and triple-negative breast cancers
使用恩曲替尼和帕克替尼双重抑制TrkA和JAK2通路可抑制HER2阳性和三阴性乳腺癌的生长和转移。
期刊:Cancer Letters
影响因子:10.1
doi:10.1016/j.canlet.2024.217023
Regua, Angelina T; Bindal, Shivani; Najjar, Mariana K; Zhuang, Chuling; Khan, Munazza; Arrigo, Austin B J; Gonzalez, Anneliese O; Zhang, Xinhai R; Zhu, Jay-Jiguang; Watabe, Kounosuke; Lo, Hui-Wen
肿瘤
Trk
HER2
肿瘤免疫
JAK/STAT
信号转导
乳腺癌
JAK2
