日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

ORMDL mislocalization by impaired autophagy in Niemann-Pick type C disease leads to increased de novo sphingolipid biosynthesis

尼曼匹克 C 型疾病中自噬受损导致 ORMDL 错误定位,从而导致从头鞘脂生物合成增加

Ryan D R Brown, Usha Mahawar, Binks W Wattenberg, Sarah Spiegel

Ceramide sensing by human SPT-ORMDL complex for establishing sphingolipid homeostasis

人类 SPT-ORMDL 复合物通过神经酰胺感应来建立鞘脂稳态

Tian Xie #, Peng Liu #, Xinyue Wu, Feitong Dong, Zike Zhang, Jian Yue, Usha Mahawar, Faheem Farooq, Hisham Vohra, Qi Fang, Wenchen Liu, Binks W Wattenberg, Xin Gong

CRISPR/Cas9 deletion of ORMDLs reveals complexity in sphingolipid metabolism

CRISPR/Cas9 删除 ORMDLs 揭示鞘脂代谢的复杂性

Christopher D Green, Cynthia Weigel, Clement Oyeniran, Briana N James, Deanna Davis, Usha Mahawar, Jason Newton, Binks W Wattenberg, Michael Maceyka, Sarah Spiegel

Dynamics of sphingolipids and the serine palmitoyltransferase complex in rat oligodendrocytes during myelination

大鼠少突胶质细胞髓鞘形成过程中鞘脂和丝氨酸棕榈酰转移酶复合物的动态

Deanna L Davis, Usha Mahawar, Victoria S Pope, Jeremy Allegood, Carmen Sato-Bigbee, Binks W Wattenberg

The ORMDL/Orm-serine palmitoyltransferase (SPT) complex is directly regulated by ceramide: Reconstitution of SPT regulation in isolated membranes

ORMDL/Orm-丝氨酸棕榈酰转移酶 (SPT) 复合物直接受神经酰胺调控:在分离膜中重建 SPT 调控

Deanna L Davis, Kenneth Gable, John Suemitsu, Teresa M Dunn, Binks W Wattenberg

Intra- and intercellular trafficking in sphingolipid metabolism in myelination

髓鞘形成过程中鞘脂代谢的细胞内和细胞间运输

Wattenberg, Binks W

The long and the short of ceramides

神经酰胺的长短

Wattenberg, Binks W

Sphingosine-1-phosphate receptor-2 mediated NFκB activation contributes to tumor necrosis factor-α induced VCAM-1 and ICAM-1 expression in endothelial cells

鞘氨醇-1-磷酸受体-2 介导的 NFκB 激活促进肿瘤坏死因子-α 诱导的内皮细胞 VCAM-1 和 ICAM-1 表达

Wenliang Zhang, Jin An, Hiba Jawadi, Deanna L Siow, Jen-Fu Lee, Jiawei Zhao, Allison Gartung, Krishna Rao Maddipati, Kenneth V Honn, Binks W Wattenberg, Menq-Jer Lee

Intracellular localization of sphingosine kinase 1 alters access to substrate pools but does not affect the degradative fate of sphingosine-1-phosphate

鞘氨醇激酶 1 的细胞内定位改变了对底物池的访问,但不影响鞘氨醇-1-磷酸的降解命运

Deanna L Siow, Charles D Anderson, Evgeny V Berdyshev, Anastasia Skobeleva, Stuart M Pitson, Binks W Wattenberg

Role of sphingosine kinase localization in sphingolipid signaling

鞘氨醇激酶定位在鞘脂信号传导中的作用

Wattenberg, Binks W