日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Chronic AMPK inactivation slows SHH medulloblastoma progression by inhibiting mTORC1 signaling and depleting tumor stem cells

慢性 AMPK 失活通过抑制 mTORC1 信号传导和消耗肿瘤干细胞来减缓 SHH 髓母细胞瘤进展

Daniel Shiloh Malawsky, Taylor Dismuke, Hedi Liu, Ethan Castellino, Jay Brenman, Biplab Dasgupta, Andrey Tikunov, Timothy R Gershon

Brain pharmacokinetics and metabolism of the AMP-activated protein kinase selective inhibitor SBI-0206965, an investigational agent for the treatment of glioblastoma

AMP 活化蛋白激酶选择性抑制剂 SBI-0206965(一种治疗胶质母细胞瘤的试验药物)的脑药代动力学和代谢

Janki M Desai, Aniruddha S Karve, Gary A Gudelsky, Mruniya V Gawali, William Seibel, Larry Sallans, Biplab DasGupta, Pankaj B Desai

Potentiation of temozolomide activity against glioblastoma cells by aromatase inhibitor letrozole

芳香化酶抑制剂来曲唑增强替莫唑胺对胶质母细胞瘤细胞的活性

Aniruddha S Karve, Janki M Desai, Nimita Dave, Trisha M Wise-Draper, Gary A Gudelsky, Timothy N Phoenix, Biplab DasGupta, Soma Sengupta, David R Plas, Pankaj B Desai

Analysis of reactive astrogliosis in mouse brain using in situ hybridization combined with immunohistochemistry

原位杂交结合免疫组化技术分析小鼠脑反应性星形胶质增生

Ranjithmenon Muraleedharan, Diana Nardini, Ronald Raymond Waclaw, Biplab Dasgupta

AMPK-Regulated Astrocytic Lactate Shuttle Plays a Non-Cell-Autonomous Role in Neuronal Survival

AMPK调控的星形胶质细胞乳酸穿梭在神经元存活中发挥非细胞自主性作用

Ranjithmenon Muraleedharan ,Mruniya V Gawali ,Durgesh Tiwari ,Abitha Sukumaran ,Nicole Oatman ,Jane Anderson ,Diana Nardini ,Mohammad Alfrad Nobel Bhuiyan ,Ivan Tkáč ,Amber Lynne Ward ,Mondira Kundu ,Ronald Waclaw ,Lionel M Chow ,Christina Gross ,Raghavendra Rao ,Stefanie Schirmeier ,Biplab Dasgupta

AMP kinase promotes glioblastoma bioenergetics and tumour growth

AMP激酶促进胶质母细胞瘤的生物能量学和肿瘤生长

Rishi Raj Chhipa ,Qiang Fan ,Jane Anderson ,Ranjithmenon Muraleedharan ,Yan Huang ,Georgianne Ciraolo ,Xiaoting Chen ,Ronald Waclaw ,Lionel M Chow ,Zaza Khuchua ,Matthew Kofron ,Matthew T Weirauch ,Ady Kendler ,Christopher McPherson ,Nancy Ratner ,Ichiro Nakano ,Nupur Dasgupta ,Kakajan Komurov ,Biplab Dasgupta

Fatty acid synthase is a metabolic oncogene targetable in malignant peripheral nerve sheath tumors

脂肪酸合酶是一种可靶向治疗恶性周围神经鞘瘤的代谢致癌基因

Ami V Patel, Gunnar Johansson, Melissa C Colbert, Biplab Dasgupta, Nancy Ratner

The tumour suppressor LKB1 regulates myelination through mitochondrial metabolism

肿瘤抑制因子 LKB1 通过线粒体代谢调节髓鞘形成

Shabnam Pooya, Xiaona Liu, V B Sameer Kumar, Jane Anderson, Fumiyasu Imai, Wujuan Zhang, Georgianne Ciraolo, Nancy Ratner, Kenneth D R Setchell, Yutaka Yoshida, Michael P Jankowski, Biplab Dasgupta

Neurofibromin regulates neural stem cell proliferation, survival, and astroglial differentiation in vitro and in vivo

神经纤维蛋白在体内和体外调节神经干细胞增殖、存活和星形胶质细胞分化

Biplab Dasgupta, David H Gutmann