日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Granzyme A inhibition reduces inflammation and increases survival during abdominal sepsis

颗粒酶A抑制剂可减轻炎症并提高腹腔脓毒症患者的存活率

Garzón-Tituaña, Marcela; Sierra-Monzón, José L; Comas, Laura; Santiago, Llipsy; Khaliulina-Ushakova, Tatiana; Uranga-Murillo, Iratxe; Ramirez-Labrada, Ariel; Tapia, Elena; Morte-Romea, Elena; Algarate, Sonia; Couty, Ludovic; Camerer, Eric; Bird, Phillip I; Seral, Cristina; Luque, Pilar; Paño-Pardo, José R; Galvez, Eva M; Pardo, Julián; Arias, Maykel

SerpinB1 controls encephalitogenic T helper cells in neuroinflammation

SerpinB1 控制神经炎症中的致脑炎性 T 辅助细胞

Hou, Lifei; Rao, Deepak A; Yuki, Koichi; Cooley, Jessica; Henderson, Lauren A; Jonsson, A Helena; Kaiserman, Dion; Gorman, Mark P; Nigrovic, Peter A; Bird, Phillip I; Becher, Burkhard; Remold-O'Donnell, Eileen

Characterization of Lgr5+ progenitor cell transcriptomes in the apical and basal turns of the mouse cochlea.

小鼠耳蜗顶端和基底回中 Lgr5+ 祖细胞转录组的特征分析

Waqas Muhammad, Guo Luo, Zhang Shasha, Chen Yan, Zhang Xiaoli, Wang Lei, Tang Mingliang, Shi Haibo, Bird Phillip I, Li Huawei, Chai Renjie

Cathepsin H is an additional convertase of pro-granzyme B

组织蛋白酶H是前颗粒酶B的另一种转化酶。

D'Angelo, Michael E; Bird, Phillip I; Peters, Christoph; Reinheckel, Thomas; Trapani, Joseph A; Sutton, Vivien R

Serpins flex their muscle: II. Structural insights into target peptidase recognition, polymerization, and transport functions

丝氨酸蛋白酶抑制剂展现其强大功能:II. 靶肽酶识别、聚合和转运功能的结构解析

Whisstock, James C; Silverman, Gary A; Bird, Phillip I; Bottomley, Stephen P; Kaiserman, Dion; Luke, Cliff J; Pak, Stephen C; Reichhart, Jean-Marc; Huntington, James A

Serpins flex their muscle. I. PUTTING THE CLAMPS ON PROTEOLYSIS IN DIVERSE BIOLOGICAL SYSTEMS

丝氨酸蛋白酶抑制剂(Serpins)展现其强大功能。I. 在多种生物系统中抑制蛋白质水解

Jiang, Shuxian; Zagozdzon, Radoslaw; Jorda, Meritxell Alberich; Parmar, Kalindi; Fu, Yigong; Williams, John S; Wood, Jodi Anne T; Makriyannis, Alexandros; Banu, Naheed; Avraham, Shalom; Groopman, Jerome E; Avraham, Hava Karsenty; Lee, Moonhee; Soldato, Piero Del; Sparatore, Anna; McGeer, Patrick; Cleveland, Sean B; Davies, John; McClure, Marcella A; Namgoong, Gwang Mo; Khanal, Prem; Cho, Hae-Guk; Lim, Sung-Chul; Oh, Yoon Kyeong; Kang, Bong Seok; Shim, Jung-Hyun; Yoo, Jin-Cheol; Choi, Hong Seok; Silverman, Gary A; Whisstock, James C; Bottomley, Stephen P; Huntington, James A; Kaiserman, Dion; Luke, Cliff J; Pak, Stephen C; Reichhart, Jean-Marc; Bird, Phillip I

Serpins flex their muscle: I. Putting the clamps on proteolysis in diverse biological systems

丝氨酸蛋白酶抑制剂(Serpins)大显身手:I. 在多种生物系统中抑制蛋白水解

Silverman, Gary A; Whisstock, James C; Bottomley, Stephen P; Huntington, James A; Kaiserman, Dion; Luke, Cliff J; Pak, Stephen C; Reichhart, Jean-Marc; Bird, Phillip I

Active and zymogen forms of granzyme B are constitutively released from cytotoxic lymphocytes in the absence of target cell engagement

在没有靶细胞参与的情况下,细胞毒性淋巴细胞会持续释放颗粒酶 B 的活性和酶原形式

Monica D Prakash, Catherina H Bird, Phillip I Bird

Cationic sites on granzyme B contribute to cytotoxicity by promoting its uptake into target cells

颗粒酶B上的阳离子位点通过促进其被靶细胞摄取而发挥细胞毒性作用。

Bird, Catherina H; Sun, Jiuru; Ung, Kheng; Karambalis, Diana; Whisstock, James C; Trapani, Joseph A; Bird, Phillip I

Targeted disruption of SPI3/Serpinb6 does not result in developmental or growth defects, leukocyte dysfunction, or susceptibility to stroke

靶向破坏 SPI3/Serpinb6 不会导致发育或生长缺陷、白细胞功能障碍或中风易感性。

Scarff, Katrina L; Ung, Kheng S; Nandurkar, Harshal; Crack, Peter J; Bird, Catherina H; Bird, Phillip I