日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Distinct response to IL-1β blockade in liver- and lung-specific metastasis mouse models of pancreatic cancer with heterogeneous tumor microenvironments

在具有异质性肿瘤微环境的胰腺癌肝转移和肺转移小鼠模型中，对IL-1β阻断的反应截然不同

期刊:Experimental Hematology & Oncology
影响因子:13.5
doi:10.1186/s40164-025-00607-w
Chen, Sophia Y; Kung, Heng-Chung; Espinoza, Birginia; Washington, India; Chen, Kai; Mu, Kaiyi; Zlomke, Haley; Loycano, Michael; Wang, Rulin; Burns, William R; Fu, Juan; Zheng, Lei
肿瘤
胰腺癌
肿瘤免疫
IL-1β
肿瘤微环境
发表日期：2025
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Chemotherapy in synergy with innate immune agonists enhances T cell priming for checkpoint inhibitor treatment in pancreatic cancer

化疗与先天免疫激动剂协同作用可增强胰腺癌中T细胞的启动，从而促进免疫检查点抑制剂治疗。

期刊:Biomarker Research
影响因子:11.5
doi:10.1186/s40364-024-00721-7
Niu, Nan; Li, Keyu; Wang, Junke; Funes, Vanessa; Espinoza, Birginia; Li, Pan; Wang, Jianxin; Lyman, Melissa; He, Mengni; Herbst, Brian; Wichroski, Michael; Novosiadly, Ruslan; Shoucair, Sami; Mou, Yiping; Zheng, Lei
肿瘤
T细胞
肿瘤免疫
细胞生物学
T细胞
胰腺癌
免疫/内分泌
发表日期：2025
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Overcome the challenge for intratumoral injection of STING agonist for pancreatic cancer by systemic administration

通过全身给药克服胰腺癌瘤内注射STING激动剂的挑战

期刊:Journal of Hematology & Oncology
影响因子:40.4
doi:10.1186/s13045-024-01576-z
Li, Keyu; Wang, Junke; Zhang, Rui; Zhou, Jiawei; Espinoza, Birginia; Niu, Nan; Wang, Jianxin; Jurcak, Noelle; Rozich, Noah; Osipov, Arsen; Henderson, MacKenzie; Funes, Vanessa; Lyman, Melissa; Blair, Alex B; Herbst, Brian; He, Mengni; Yuan, Jialong; Trafton, Diego; Yuan, Chunhui; Wichroski, Michael; Liu, Xubao; Fu, Juan; Zheng, Lei
胰腺癌
肿瘤
肿瘤免疫
STING
发表日期：2024
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Targeting heterogeneous tumor microenvironments in pancreatic cancer mouse models of metastasis by TGF-β depletion

通过TGF-β耗竭靶向胰腺癌小鼠转移模型中的异质性肿瘤微环境

期刊:JCI Insight
影响因子:6.1
doi:10.1172/jci.insight.182766
Chen, Sophia Y; Kung, Heng-Chung; Espinoza, Birginia; Washington, India; Chen, Kai; Wang, Jianxin; Zlomke, Haley; Loycano, Michael; Wang, Rulin; Pickup, Michael; Burns, William R 3rd; Fu, Juan; Hwang, William L; Zheng, Lei
肿瘤
肿瘤免疫
TGF-β
胰腺癌
肿瘤微环境
发表日期：2024
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CLDN18.2 BiTE Engages Effector and Regulatory T Cells for Antitumor Immune Response in Preclinical Models of Pancreatic Cancer

CLDN18.2 BiTE 在胰腺癌临床前模型中激活效应 T 细胞和调节性 T 细胞，从而促进抗肿瘤免疫反应

期刊:Gastroenterology
影响因子:25.1
doi:10.1053/j.gastro.2023.06.037
Xu, Yao; Fu, Juan; Henderson, MacKenzie; Lee, Fei; Jurcak, Noelle; Henn, Anja; Wahl, Joachim; Shao, Yingkuan; Wang, Jianxin; Lyman, Melissa; Funes, Vanessa; Espinoza, Birginia; Zhang, Rui; Washington, India; Chen, Sophia Y; Zlomke, Haley; Wang, Junke; Niu, Nan; Li, Pan; Meng, Fengxi; Burns, William; Friedrich, Matthias; Stienen, Sabine; Bailis, Julie M; Zheng, Lei
CLDN1
肿瘤
T细胞
肿瘤免疫
细胞生物学
胰腺癌
免疫/内分泌
发表日期：2023
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CCR2/CCR5 inhibitor permits the radiation-induced effector T cell infiltration in pancreatic adenocarcinoma

CCR2/CCR5 抑制剂可促进胰腺腺癌中辐射诱导的效应 T 细胞浸润

期刊:Journal of Experimental Medicine
影响因子:12.6
doi:10.1084/jem.20211631
Jianxin Wang #, May Tun Saung #, Keyu Li, Juan Fu, Kenji Fujiwara, Nan Niu, Stephen Muth, Junke Wang, Yao Xu, Noah Rozich, Haley Zlomke, Sophia Chen, Birginia Espinoza, MacKenzie Henderson, Vanessa Funes, Brian Herbst, Ding Ding, Christina Twyman-Saint Victor, Qihong Zhao, Amol Narang, Jin He, Lei Z
免疫
细胞生物学
胰腺癌
肿瘤细胞
发表日期：2022
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