日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

PARP1 expression predicts PARP inhibitor sensitivity and correlates with metastatic potential and overall survival in melanoma

PARP1 表达可预测 PARP 抑制剂敏感性,并与黑色素瘤的转移潜能和总体生存率相关

Lisa Marie Fröhlich, Ana Villar-Miyar, Tamara Heintze, Birgit Sauer, Birgit Schittek

Histological and functional characterization of 3D human skin models mimicking the inflammatory skin diseases psoriasis and atopic dermatitis

模拟炎症性皮肤病牛皮癣和特应性皮炎的 3D 人体皮肤模型的组织学和功能特征

Jasmin Scheurer, Birgit Sauer, Jule Focken, Martina Giampetraglia, Annika Jäger, Christian M Schürch, Bettina Weigelin, Birgit Schittek

Inhibition of p90 ribosomal S6 kinases disrupts melanoma cell growth and immune evasion

抑制 p90 核糖体 S6 激酶可破坏黑色素瘤细胞生长和免疫逃避

Corinna Kosnopfel, Simone Wendlinger, Heike Niessner, Johannes Siewert, Tobias Sinnberg, Angelika Hofmann, Jonas Wohlfarth, David Schrama, Marion Berthold, Claudia Siedel, Birgit Sauer, Aarthi Jayanthan, Georg Lenz, Sandra E Dunn, Bastian Schilling, Birgit Schittek

PARP Inhibitors Effectively Reduce MAPK Inhibitor Resistant Melanoma Cell Growth and Synergize with MAPK Inhibitors through a Synthetic Lethal Interaction In Vitro and In Vivo

PARP 抑制剂可有效降低 MAPK 抑制剂耐药性黑色素瘤细胞的生长,并通过体内外合成致死相互作用与 MAPK 抑制剂产生协同作用

Lisa Marie Fröhlich, Heike Niessner, Birgit Sauer, Sofie Kämereit, Eftychia Chatziioannou, Simon Riel, Tobias Sinnberg, Birgit Schittek

Targeting Rad51 as a strategy for the treatment of melanoma cells resistant to MAPK pathway inhibition

以 Rad51 为靶点,作为治疗对 MAPK 通路抑制有抗性的黑色素瘤细胞的策略

Elena Makino, Lisa Marie Fröhlich, Tobias Sinnberg, Corinna Kosnopfel, Birgit Sauer, Claus Garbe, Birgit Schittek

Tumour Progression Stage-Dependent Secretion of YB-1 Stimulates Melanoma Cell Migration and Invasion

肿瘤进展阶段依赖性YB-1分泌刺激黑色素瘤细胞迁移和侵袭

Corinna Kosnopfel, Tobias Sinnberg, Birgit Sauer, Heike Niessner, Alina Muenchow, Birgit Fehrenbacher, Martin Schaller, Peter R Mertens, Claus Garbe, Basant Kumar Thakur, Birgit Schittek

Lugdunin amplifies innate immune responses in the skin in synergy with host- and microbiota-derived factors

卢格杜宁与宿主和微生物群来源的因子协同作用,增强皮肤的固有免疫反应。

Katharina Bitschar ,Birgit Sauer ,Jule Focken ,Hanna Dehmer ,Sonja Moos ,Martin Konnerth ,Nadine A Schilling ,Stephanie Grond ,Hubert Kalbacher ,Florian C Kurschus ,Friedrich Götz ,Bernhard Krismer ,Andreas Peschel ,Birgit Schittek

PTEN regulates IGF-1R-mediated therapy resistance in melanoma

PTEN 调控黑色素瘤中 IGF-1R 介导的治疗耐药性

Jun Wang, Tobias Sinnberg, Heike Niessner, Rebecca Dölker, Birgit Sauer, Wolfgang E Kempf, Friedegund Meier, Nick Leslie, Birgit Schittek