日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

No magnesium is needed for binding of the stimulator of interferon genes to cyclic dinucleotides

干扰素基因刺激因子与环状二核苷酸结合不需要镁离子。

Smola, Miroslav; Birkus, Gabriel; Boura, Evzen

Nucleotide Prodrug Containing a Nonproteinogenic Amino Acid To Improve Oral Delivery of a Hepatitis C Virus Treatment

含有非蛋白源性氨基酸的核苷酸前药可改善丙型肝炎病毒治疗药物的口服递送

Feng, Joy Y; Wang, Ting; Park, Yeojin; Babusis, Darius; Birkus, Gabriel; Xu, Yili; Voitenleitner, Christian; Fenaux, Martijn; Yang, Huiling; Eng, Stacey; Tirunagari, Neeraj; Kirschberg, Thorsten; Cho, Aesop; Ray, Adrian S

Biochemical characterization of recombinant influenza A polymerase heterotrimer complex: Polymerase activity and mechanisms of action of nucleotide analogs

重组甲型流感病毒聚合酶异源三聚体复合物的生化特性:聚合酶活性和核苷酸类似物的作用机制

Barauskas, Ona; Xing, Weimei; Aguayo, Esmeralda; Willkom, Madeleine; Sapre, Annapurna; Clarke, Michael; Birkus, Gabriel; Schultz, Brian E; Sakowicz, Roman; Kwon, HyockJoo; Feng, Joy Y

Biochemical characterization of recombinant influenza A polymerase heterotrimer complex: Endonuclease activity and evaluation of inhibitors.

重组甲型流感聚合酶异三聚体复合物的生化特性:核酸内切酶活性及抑制剂评价

Xing Weimei, Barauskas Ona, Kirschberg Thorsten, Niedziela-Majka Anita, Clarke Michael, Birkus Gabriel, Weissburg Perry, Liu Xiaohong, Schultz Brian E, Sakowicz Roman, Kwon HyockJoo, Feng Joy Y

Purine analogs as phosphatidylinositol 4-kinase IIIβ inhibitors

嘌呤类似物作为磷脂酰肌醇4-激酶IIIβ抑制剂

Šála, Michal; Kögler, Martin; Plačková, Pavla; Mejdrová, Ivana; Hřebabecký, Hubert; Procházková, Eliška; Strunin, Dmytro; Lee, Gary; Birkus, Gabriel; Weber, Jan; Mertlíková-Kaiserová, Helena; Nencka, Radim

Contribution of the organic anion transporter OAT2 to the renal active tubular secretion of creatinine and mechanism for serum creatinine elevations caused by cobicistat

有机阴离子转运蛋白OAT2对肾脏主动小管分泌肌酐的贡献以及考比司他引起血清肌酐升高的机制

Lepist, Eve-Irene; Zhang, Xuexiang; Hao, Jia; Huang, Jane; Kosaka, Alan; Birkus, Gabriel; Murray, Bernard P; Bannister, Roy; Cihlar, Tomas; Huang, Yong; Ray, Adrian S

Multiple classes of antiviral agents exhibit in vitro activity against human rhinovirus type C

多种抗病毒药物在体外对人鼻病毒C型表现出活性。

Mello, Chris; Aguayo, Esmeralda; Rodriguez, Madeleine; Lee, Gary; Jordan, Robert; Cihlar, Tomas; Birkus, Gabriel

Evaluation of the effect of cobicistat on the in vitro renal transport and cytotoxicity potential of tenofovir.

评价考比司他(cobicistat)对替诺福韦体外肾脏转运和细胞毒性潜力的影响

Stray Kirsten M, Bam Rujuta A, Birkus Gabriel, Hao Jia, Lepist Eve-Irene, Yant Stephen R, Ray Adrian S, Cihlar Tomas