Birnir相关文献与解析，生知库 | 链接生命科学的每一步

Inhibition of the Na(+)-glucose transporter SGLT2 reduces glucose uptake and IFNÎ³ release from activated human CD4(+) T cells.

抑制 Na(+)-葡萄糖转运蛋白 SGLT2 可减少活化的人类 CD4(+) T 细胞对葡萄糖的摄取和 IFNγ 的释放

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2025.1576216

Jin Zhe, Hammoud Hayma, Bhandage Amol K, Koreli Stasini, Chowdhury Azazul Islam, Bergsten Peter, Birnir Bryndis

GLP-1 selectively enhances tonic GABA(A) receptor-mediated currents in mouse dentate gyrus granule cells of the ventral hippocampus

GLP-1选择性地增强小鼠腹侧海马齿状回颗粒细胞中GABA(A)受体介导的强直性电流

期刊:Frontiers in Cellular Neuroscience

影响因子:4

doi:10.3389/fncel.2025.1638550

Netsyk, Olga; Korol, Sergiy V; Birnir, Bryndis; Jin, Zhe

Rodent islet amyloid polypeptide (IAPP) selectively enhances GABA (A) receptor-mediated neuronal inhibition in mouse ventral but not dorsal hippocampal dentate gyrus granule cells.

啮齿动物胰岛淀粉样多肽（IAPP）选择性地增强小鼠腹侧而非背侧海马齿状回颗粒细胞中GABA（A）受体介导的神经元抑制

期刊:Frontiers in Cellular Neuroscience

影响因子:4

doi:10.3389/fncel.2025.1531790

Netsyk Olga, Korol Sergiy V, Westermark Gunilla T, Birnir Bryndis, Jin Zhe

Long-term gamma-aminobutyric acid (GABA) treatment fails to regain beta-cell function in longstanding type 1 diabetes in a randomized trial

一项随机试验表明，长期使用γ-氨基丁酸（GABA）治疗未能使长期患有1型糖尿病的患者的β细胞功能恢复。

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-025-95751-y

Hill, Henrik; Lundkvist, Per; Tsatsaris, Georgios; Birnir, Bryndis; Espes, Daniel; Carlsson, Per-Ola

GABA-activated slow spontaneous inhibitory postsynaptic currents are decreased in dorsal hippocampal dentate gyrus granule cells in an aged mouse model of Alzheimer's disease

在老年阿尔茨海默病小鼠模型中，背侧海马齿状回颗粒细胞中GABA激活的慢速自发性抑制性突触后电流减少。

期刊:Journal of Alzheimers Disease

影响因子:3.1

doi:10.1177/13872877251317608

Netsyk, Olga; Korol, Sergiy V; Li, Jin-Ping; Birnir, Bryndis; Jin, Zhe

GABA-mediated inhibition of human CD4+ T cell functions is enhanced by insulin but impaired by high glucose levels

胰岛素可增强GABA介导的对人CD4+ T细胞功能的抑制作用，但高血糖水平会削弱这种抑制作用。

期刊:EBioMedicine

影响因子:9.7

doi:10.1016/j.ebiom.2024.105217

Zhe Jin ，Hayma Hammoud ，Amol Keshavasa Bhandage ，Sergiy Vasylyovych Korol ，Olivia Trujeque-Ramos ，Stasini Koreli ，Zhitao Gong ，Azasul Islam Chowdhury ，Friederike Andrea Sandbaumhüter ，Erik Tomas Jansson ，Robin Sean Lindsay ，Gustaf Christoffersson ，Per Erik Andrén ，Per-Ola Carlsson ，Peter Bergsten ，Masood Kamali-Moghaddam ，Bryndis Birnir

Coding with the machines: machine-assisted coding of rare event data

利用机器进行编码：机器辅助对罕见事件数据进行编码

期刊:PNAS Nexus

影响因子:3.8

doi:10.1093/pnasnexus/pgae165

Overos, Henry David; Hlatky, Roman; Pathak, Ojashwi; Goers, Harriet; Gouws-Dewar, Jordan; Smith, Katy; Chew, Keith Padraic; Birnir, Jóhanna K; Liu, Amy H

发表日期：2024

文献求助收藏

Monoallelic and bi-allelic variants in NCDN cause neurodevelopmental delay, intellectual disability, and epilepsy

NCDN基因的单等位基因和双等位基因变异会导致神经发育迟缓、智力障碍和癫痫。

期刊:American Journal of Human Genetics

影响因子:8.1

doi:10.1016/j.ajhg.2022.02.007

Fatima, Ambrin; Hoeber, Jan; Schuster, Jens; Koshimizu, Eriko; Maya-Gonzalez, Carolina; Keren, Boris; Mignot, Cyril; Akram, Talia; Ali, Zafar; Miyatake, Satoko; Tanigawa, Junpei; Koike, Takayoshi; Kato, Mitsuhiro; Murakami, Yoshiko; Abdullah, Uzma; Ali, Muhammad Akhtar; Fadoul, Rein; Laan, Loora; Castillejo-López, Casimiro; Liik, Maarika; Jin, Zhe; Birnir, Bryndis; Matsumoto, Naomichi; Baig, Shahid M; Klar, Joakim; Dahl, Niklas

Correction: Indonesia Election Archive: Institutions, candidates and results

更正：印尼选举档案：机构、候选人和结果

Indonesia Election Archive: Institutions, candidates and results

印尼选举档案：机构、候选人和结果

Inhibition of the Na(+)-glucose transporter SGLT2 reduces glucose uptake and IFNÎ³ release from activated human CD4(+) T cells.

抑制 Na(+)-葡萄糖转运蛋白 SGLT2 可减少活化的人类 CD4(+) T 细胞对葡萄糖的摄取和 IFNγ 的释放

GLP-1 selectively enhances tonic GABA(A) receptor-mediated currents in mouse dentate gyrus granule cells of the ventral hippocampus

GLP-1选择性地增强小鼠腹侧海马齿状回颗粒细胞中GABA(A)受体介导的强直性电流

Rodent islet amyloid polypeptide (IAPP) selectively enhances GABA (A) receptor-mediated neuronal inhibition in mouse ventral but not dorsal hippocampal dentate gyrus granule cells.

啮齿动物胰岛淀粉样多肽（IAPP）选择性地增强小鼠腹侧而非背侧海马齿状回颗粒细胞中GABA（A）受体介导的神经元抑制

Long-term gamma-aminobutyric acid (GABA) treatment fails to regain beta-cell function in longstanding type 1 diabetes in a randomized trial

一项随机试验表明，长期使用γ-氨基丁酸（GABA）治疗未能使长期患有1型糖尿病的患者的β细胞功能恢复。

GABA-activated slow spontaneous inhibitory postsynaptic currents are decreased in dorsal hippocampal dentate gyrus granule cells in an aged mouse model of Alzheimer's disease

在老年阿尔茨海默病小鼠模型中，背侧海马齿状回颗粒细胞中GABA激活的慢速自发性抑制性突触后电流减少。

GABA-mediated inhibition of human CD4+ T cell functions is enhanced by insulin but impaired by high glucose levels

胰岛素可增强GABA介导的对人CD4+ T细胞功能的抑制作用，但高血糖水平会削弱这种抑制作用。

Coding with the machines: machine-assisted coding of rare event data

利用机器进行编码：机器辅助对罕见事件数据进行编码

Monoallelic and bi-allelic variants in NCDN cause neurodevelopmental delay, intellectual disability, and epilepsy

NCDN基因的单等位基因和双等位基因变异会导致神经发育迟缓、智力障碍和癫痫。