Birus相关文献与解析，生知库 | 链接生命科学的每一步

Valerie J Brock, Niels Christian Lory, Franziska Möckl, Melina Birus, Tobias Stähler, Lena-Marie Woelk, Michelle Jaeckstein, Joerg Heeren, Friedrich Koch-Nolte, Björn Rissiek, Hans-Willi Mittrücker, Andreas H Guse, René Werner, Björn-Philipp Diercks

细胞生物学

T细胞

发表日期：2024

文献求助收藏

4,5,7-Trisubstituted indeno[1,2-b]indole inhibits CK2 activity in tumor cells equivalent to CX-4945 and shows strong anti-migratory effects

4,5,7-三取代茚并[1,2-b]吲哚抑制肿瘤细胞中 CK2 活性的效果与 CX-4945 相当，并表现出强大的抗迁移作用

期刊:FEBS Open Bio

影响因子:2.8

doi:10.1002/2211-5463.13346

Robin Birus, Ehab El-Awaad, Laurens Ballentin, Faten Alchab, Dagmar Aichele, Laurent Ettouati, Claudia Götz, Marc Le Borgne, Joachim Jose

Broad-Spectrum Anticancer Activity and Pharmacokinetic Properties of a Prenyloxy-Substituted Indeno[1,2-b]indole Derivative, Discovered as CK2 Inhibitor

一种异戊烯氧基取代的茚并[1,2-b]吲哚衍生物的广谱抗癌活性和药代动力学特性，该衍生物被发现是CK2抑制剂

期刊:Pharmaceuticals

影响因子:4.8

doi:10.3390/ph14060542

El-Awaad, Ehab; Birus, Robin; Marminon, Christelle; Bouaziz, Zouhair; Ballentin, Laurens; Aichele, Dagmar; Le Borgne, Marc; Jose, Joachim

In Vitro and in Silico Evaluation of Bikaverin as a Potent Inhibitor of Human Protein Kinase CK2

体外和计算机模拟评价比卡维林作为人蛋白激酶CK2的有效抑制剂

期刊:Molecules

影响因子:4.6

doi:10.3390/molecules24071380

Haidar, Samer; Aichele, Dagmar; Birus, Robin; Hielscher, Janine; Laitinen, Tuomo; Poso, Antti; Jose, Joachim

Unexpected Binding Mode of a Potent Indeno[1,2-b]indole-Type Inhibitor of Protein Kinase CK2 Revealed by Complex Structures with the Catalytic Subunit CK2α and Its Paralog CK2α'

通过与催化亚基CK2α及其旁系同源物CK2α'的复合物结构，揭示了一种强效的茚并[1,2-b]吲哚类蛋白激酶CK2抑制剂的意外结合模式

期刊:Pharmaceuticals

影响因子:4.8

doi:10.3390/ph10040098

Hochscherf, Jennifer; Lindenblatt, Dirk; Witulski, Benedict; Birus, Robin; Aichele, Dagmar; Marminon, Christelle; Bouaziz, Zouhair; Le Borgne, Marc; Jose, Joachim; Niefind, Karsten

信号转导

发表日期：2017

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Time-resolved role of P2X4 and P2X7 during CD8+ T cell activation

P2X4 和 P2X7 在 CD8+ T 细胞活化过程中的时间分辨作用

4,5,7-Trisubstituted indeno[1,2-b]indole inhibits CK2 activity in tumor cells equivalent to CX-4945 and shows strong anti-migratory effects

4,5,7-三取代茚并[1,2-b]吲哚抑制肿瘤细胞中 CK2 活性的效果与 CX-4945 相当，并表现出强大的抗迁移作用

Broad-Spectrum Anticancer Activity and Pharmacokinetic Properties of a Prenyloxy-Substituted Indeno[1,2-b]indole Derivative, Discovered as CK2 Inhibitor

一种异戊烯氧基取代的茚并[1,2-b]吲哚衍生物的广谱抗癌活性和药代动力学特性，该衍生物被发现是CK2抑制剂

In Vitro and in Silico Evaluation of Bikaverin as a Potent Inhibitor of Human Protein Kinase CK2

体外和计算机模拟评价比卡维林作为人蛋白激酶CK2的有效抑制剂

Unexpected Binding Mode of a Potent Indeno[1,2-b]indole-Type Inhibitor of Protein Kinase CK2 Revealed by Complex Structures with the Catalytic Subunit CK2α and Its Paralog CK2α'

通过与催化亚基CK2α及其旁系同源物CK2α'的复合物结构，揭示了一种强效的茚并[1,2-b]吲哚类蛋白激酶CK2抑制剂的意外结合模式