日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The RNA-binding protein hnRNP E1 regulates p53 and p21 translation via KH1 and KH2 domain interactions with 3' UTR C-rich motifs.

RNA结合蛋白hnRNP E1通过KH1和KH2结构域与3'UTR富含C的基序相互作用来调节p53和p21的翻译。

Samanta Abhisekh, Kar Arpita, Mukherjee Sandipan, Biswas Avik

Predicting water at the protein interface in cryo-EM structures from MD-excess chemical potential

利用分子动力学模拟过量化学势预测冷冻电镜结构中蛋白质界面处的水分子

Sun, Qinfang; Aiyer, Sriram; Biswas, Avik; Haldane, Allan; Chatterjee, Sompriya; Matubayasi, Nobuyuki; Lyumkis, Dmitry; Levy, Ronald M

Oligomeric HIV-1 integrase structures reveal functional plasticity for intasome assembly and RNA binding.

寡聚体 HIV-1 整合酶结构揭示了整合体组装和 RNA 结合的功能可塑性。

Jing Tao, Shan Zelin, Dinh Tung, Biswas Avik, Jang Sooin, Greenwood Juliet, Li Min, Zhang Zeyuan, Gray Gennavieve, Shin Hye Jeong, Zhou Bo, Passos Dario, Strutzenberg Timothy S, Aiyer Sriram, Andrade Leonardo, Zhang Yuxuan, Li Zhen, Craigie Robert, Engelman Alan N, Kvaratskhelia Mamuka, Lyumkis Dmitry

De Novo Hydration of Cryo-EM Reconstructions through Molecular Dynamics Simulations of the Excess Chemical Potential

通过过剩化学势的分子动力学模拟实现冷冻电镜重建的从头水合

Sun, Qinfang; Aiyer, Sriram; Biswas, Avik; Haldane, Allan; Chatterjee, Sompriya; Matubayasi, Nobuyuki; Lyumkis, Dmitry; Levy, Ronald M

Evolutionary Sequence and Structural Basis for the Epistatic Origins of Drug Resistance in HIV

HIV药物耐药性上位起源的进化序列和结构基础

Biswas, Avik; Choudhuri, Indrani; Huang, Kenneth; Sun, Qinfang; Sali, Andrej; Echeverria, Ignacia; Haldane, Allan; Levy, Ronald M; Lyumkis, Dmitry

Kinetic coevolutionary models predict the temporal emergence of HIV-1 resistance mutations under drug selection pressure

动力学协同进化模型预测了在药物选择压力下HIV-1耐药突变的出现时间。

Biswas, Avik; Choudhuri, Indrani; Arnold, Eddy; Lyumkis, Dmitry; Haldane, Allan; Levy, Ronald M

IJCM_288A: Factors responsible for death among HIV infected patients registered in ART Centre Jabalpur, Madhya Pradesh

IJCM_288A:导致中央邦贾巴尔普尔抗逆转录病毒治疗中心登记的艾滋病毒感染者死亡的因素

Saha, Debraj; Pal, Ananya; Biswas, Avik; Panigrahi, Rajesh; Sarkar, Neelakshi; Sarkar, Jayeeta; Pal, Manisha; Guha, Subhasish Kamal; Saha, Bibhuti; Chakrabarti, Sekhar; Chakravarty, Runu; Klein, Carefirmly; Toppo, Neelam Anupama; Thakur, Aditya

Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants

HIV-1整合酶对多替拉韦产生耐药性的机制以及对耐药变异株的有效抑制

Li, Min; Oliveira Passos, Dario; Shan, Zelin; Smith, Steven J; Sun, Qinfang; Biswas, Avik; Choudhuri, Indrani; Strutzenberg, Timothy S; Haldane, Allan; Deng, Nanjie; Li, Zhaoyang; Zhao, Xue Zhi; Briganti, Lorenzo; Kvaratskhelia, Mamuka; Burke, Terrence R Jr; Levy, Ronald M; Hughes, Stephen H; Craigie, Robert; Lyumkis, Dmitry

In Silico Integration of Transcriptome and Interactome Predicts an ETP-ALL-Specific Transcriptional Footprint that Decodes its Developmental Propensity

转录组和互作组的计算机整合预测了ETP-ALL特有的转录特征,揭示了其发育倾向

Mukherjee, Soumyadeep; Kar, Arpita; Paul, Paramita; Dey, Souvik; Biswas, Avik; Barik, Subhasis

Contingency and Entrenchment of Drug-Resistance Mutations in HIV Viral Proteins

HIV病毒蛋白中耐药突变的偶然性和固化

Choudhuri, Indrani; Biswas, Avik; Haldane, Allan; Levy, Ronald M