Combining CD47 blockade with trastuzumab eliminates HER2-positive breast cancer cells and overcomes trastuzumab tolerance
CD47阻断剂与曲妥珠单抗联合使用可清除HER2阳性乳腺癌细胞并克服曲妥珠单抗耐药性。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2026849118
Upton, Rosalynd; Banuelos, Allison; Feng, Dongdong; Biswas, Tanuka; Kao, Kevin; McKenna, Kelly; Willingham, Stephen; Ho, Po Yi; Rosental, Benyamin; Tal, Michal Caspi; Raveh, Tal; Volkmer, Jens-Peter; Pegram, Mark D; Weissman, Irving L
肿瘤
T细胞
HER2
肿瘤免疫
CD47
乳腺癌
细胞生物学
CD4
