日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Blood and urine multi-omics analysis of the impact of e-vaping, smoking, and cessation: from exposome to molecular responses

血液和尿液多组学分析电子烟、吸烟和戒烟的影响:从暴露组到分子反应

Carine Poussin, Bjoern Titz, Yang Xiang, Laurel Baglia, Rachel Berg, David Bornand, Mohammed-Amin Choukrallah, Timothy Curran, Sophie Dijon, Eric Dossin, Remi Dulize, Doris Etter, Maria Fatarova, Loyse Felber Medlin, Adrian Haiduc, Edina Kishazi, Aditya R Kolli, Athanasios Kondylis, Emmanuel Kottela

Apical Medium Flow Influences the Morphology and Physiology of Human Proximal Tubular Cells in a Microphysiological System

顶端培养基流动影响微生理系统中人类近端小管细胞的形态和生理

Gabriele Specioso, David Bovard, Filippo Zanetti, Fabio Maranzano, Céline Merg, Antonin Sandoz, Bjoern Titz, Federico Dalcanale, Julia Hoeng, Kasper Renggli, Laura Suter-Dick

A 6-month inhalation toxicology study in Apoe-/- mice demonstrates substantially lower effects of e-vapor aerosol compared with cigarette smoke in the respiratory tract

一项针对 Apoe-/- 小鼠的为期 6 个月的吸入毒理学研究表明,与香烟烟雾相比,电子蒸汽气溶胶对呼吸道的影响明显较低

Ee Tsin Wong #, Justyna Szostak #, Bjoern Titz, Tom Lee, Sin Kei Wong, Oksana Lavrynenko, Celine Merg, Maica Corciulo, Jovan Simicevic, Mehdi Auberson, Dariusz Peric, Remi Dulize, David Bornand, Guo Jie Loh, Kyeonghee Monica Lee, Jingjie Zhang, John H Miller 4th, Walter K Schlage, Emmanuel Guedj, Th

Impact of whole-body versus nose-only inhalation exposure systems on systemic, respiratory, and cardiovascular endpoints in a 2-month cigarette smoke exposure study in the ApoE-/- mouse model

在 ApoE-/- 小鼠模型中进行的为期 2 个月的香烟烟雾暴露研究中,全身吸入暴露系统与仅鼻吸入暴露系统对全身、呼吸和心血管终点的影响

Ulrike Kogel, Ee Tsin Wong, Justyna Szostak, Wei Teck Tan, Francesco Lucci, Patrice Leroy, Bjoern Titz, Yang Xiang, Tiffany Low, Sin Kei Wong, Emmanuel Guedj, Nikolai V Ivanov, Walter K Schlage, Manuel C Peitsch, Arkadiusz Kuczaj, Patrick Vanscheeuwijck, Julia Hoeng

Respiratory Effects of Exposure to Aerosol From the Candidate Modified-Risk Tobacco Product THS 2.2 in an 18-Month Systems Toxicology Study With A/J Mice

在为期 18 个月的 A/J 小鼠系统毒理学研究中,暴露于候选改良风险烟草产品 THS 2.2 的气溶胶对呼吸系统的影响

Bjoern Titz, Alain Sewer, Karsta Luettich, Ee Tsin Wong, Emmanuel Guedj, Catherine Nury, Thomas Schneider, Yang Xiang, Keyur Trivedi, Grégory Vuillaume, Patrice Leroy, Ansgar Büttner, Florian Martin, Nikolai V Ivanov, Patrick Vanscheeuwijck, Julia Hoeng, Manuel C Peitsch

CRAF R391W is a melanoma driver oncogene

CRAF R391W 是黑色素瘤驱动致癌基因

Mohammad Atefi, Bjoern Titz, Jennifer Tsoi, Earl Avramis, Allison Le, Charles Ng, Anastasia Lomova, Amanda Lassen, Michael Friedman, Bartosz Chmielowski, Antoni Ribas, Thomas G Graeber

Combination of pan-RAF and MEK inhibitors in NRAS mutant melanoma

泛 RAF 和 MEK 抑制剂联合治疗 NRAS 突变黑色素瘤

Mohammad Atefi, Bjoern Titz, Earl Avramis, Charles Ng, Deborah J L Wong, Amanda Lassen, Michael Cerniglia, Helena Escuin-Ordinas, David Foulad, Begonya Comin-Anduix, Thomas G Graeber, Antoni Ribas

Effects of MAPK and PI3K pathways on PD-L1 expression in melanoma

MAPK和PI3K通路对黑色素瘤中PD-L1表达的影响

Mohammad Atefi ,Earl Avramis ,Amanda Lassen ,Deborah J L Wong ,Lidia Robert ,David Foulad ,Michael Cerniglia ,Bjoern Titz ,Thinle Chodon ,Thomas G Graeber ,Begonya Comin-Anduix ,Antoni Ribas

RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E)

RAF 抑制剂耐药性是由异常剪接的 BRAF(V600E)二聚化介导的

Poulikos I Poulikakos, Yogindra Persaud, Manickam Janakiraman, Xiangju Kong, Charles Ng, Gatien Moriceau, Hubing Shi, Mohammad Atefi, Bjoern Titz, May Tal Gabay, Maayan Salton, Kimberly B Dahlman, Madhavi Tadi, Jennifer A Wargo, Keith T Flaherty, Mark C Kelley, Tom Misteli, Paul B Chapman, Jeffrey A