Blackwell T Keith相关文献与解析，生知库

Fatty acid regulation of feeding in Caenorhabditis elegans reveals the potential ancestral origin of a GLP-1-like multiagonist signaling system

秀丽隐杆线虫中脂肪酸对摄食的调控揭示了GLP-1样多激动剂信号系统的潜在祖先起源

期刊:Proceedings of the National Academy of Sciences of the United States of America

Zhu, Feimei; Castillo-Quan, Jorge Iván; Ogawa, Takafumi; Wu, Ziyun; Ding, Lang; Sura, Mansi; Watanabe, Yoshiyuki; Lentschat, Hannah; Fernández-Cárdenas, L Paulette; Dag, Ugur; Beck-Sickinger, Annette; Wang, Meng C; Kahn, C Ronald; Blackwell, T Keith

Nutrient control of growth and metabolism through mTORC1 regulation of mRNA splicing.

通过 mTORC1 调控 mRNA 剪接来控制生长和代谢的营养物质。

期刊:Molecular Cell

影响因子:16.6

doi:10.1016/j.molcel.2024.10.037

Ogawa Takafumi, Isik Meltem, Wu Ziyun, Kurmi Kiran, Meng Jin, Cho Sungyun, Lee Gina, Fernandez-Cardenas L Paulette, Mizunuma Masaki, Blenis John, Haigis Marcia C, Blackwell T Keith

Mild mitochondrial impairment enhances innate immunity and longevity through ATFS-1 and p38 signaling

轻度线粒体功能障碍可通过ATFS-1和p38信号通路增强先天免疫力和延长寿命

期刊:EMBO Reports

影响因子:6.2

doi:10.15252/embr.202152964

Campos, Juliane C; Wu, Ziyun; Rudich, Paige D; Soo, Sonja K; Mistry, Meeta; Ferreira, Julio Cb; Blackwell, T Keith; Van Raamsdonk, Jeremy M

Dietary Restriction Extends Lifespan through Metabolic Regulation of Innate Immunity.

饮食限制通过代谢调节先天免疫力来延长寿命

期刊:Cell Metabolism

影响因子:30.9

doi:10.1016/j.cmet.2019.02.013

Wu Ziyun, Isik Meltem, Moroz Natalie, Steinbaugh Michael J, Zhang Peng, Blackwell T Keith

代谢

发表日期：2019

文献求助收藏

Mitochondrial unfolded protein response transcription factor ATFS-1 promotes longevity in a long-lived mitochondrial mutant through activation of stress response pathways

线粒体未折叠蛋白反应转录因子ATFS-1通过激活应激反应通路促进长寿线粒体突变体的寿命

期刊:BMC Biology

影响因子:4.5

doi:10.1186/s12915-018-0615-3

Wu, Ziyun; Senchuk, Megan M; Dues, Dylan J; Johnson, Benjamin K; Cooper, Jason F; Lew, Leira; Machiela, Emily; Schaar, Claire E; DeJonge, Heather; Blackwell, T Keith; Van Raamsdonk, Jeremy M

Untangling Longevity, Dauer, and Healthspan in Caenorhabditis elegans Insulin/IGF-1-Signalling

解析秀丽隐杆线虫的寿命、滞育和健康寿命：胰岛素/IGF-1信号通路

期刊:Gerontology

影响因子:3

doi:10.1159/000480504

Ewald, Collin Yvès; Castillo-Quan, Jorge Iván; Blackwell, T Keith

NADPH oxidase-mediated redox signaling promotes oxidative stress resistance and longevity through memo-1 in C. elegans

NADPH氧化酶介导的氧化还原信号通过秀丽隐杆线虫中的memo-1促进氧化应激抵抗和延长寿命

期刊:Elife

影响因子:6.4

doi:10.7554/eLife.19493

Ewald, Collin Yvès; Hourihan, John M; Bland, Monet S; Obieglo, Carolin; Katic, Iskra; Moronetti Mazzeo, Lorenza E; Alcedo, Joy; Blackwell, T Keith; Hynes, Nancy E

RNAi screening implicates a SKN-1-dependent transcriptional response in stress resistance and longevity deriving from translation inhibition.

RNAi 筛选表明，SKN-1 依赖的转录反应与抗逆性和长寿有关，这种抗逆性和长寿源于翻译抑制

期刊:PLoS Genetics

影响因子:3.7

doi:10.1371/journal.pgen.1001048

Wang Jinling, Robida-Stubbs Stacey, Tullet Jennifer M A, Rual Jean-FranÃ§ois, Vidal Marc, Blackwell T Keith

信号转导

发表日期：2010

文献求助收藏

Germline survival and apoptosis

生殖细胞存活与凋亡

期刊:

影响因子:

doi:10.1895/wormbook.1.145.1

Gartner, Anton; Boag, Peter R; Blackwell, T Keith

p38 MAPK orchestrates cross-tissue potassium homeostasis for survival

p38 MAPK 协调跨组织钾稳态以维持生存

Fatty acid regulation of feeding in Caenorhabditis elegans reveals the potential ancestral origin of a GLP-1-like multiagonist signaling system

秀丽隐杆线虫中脂肪酸对摄食的调控揭示了GLP-1样多激动剂信号系统的潜在祖先起源

Nutrient control of growth and metabolism through mTORC1 regulation of mRNA splicing.

通过 mTORC1 调控 mRNA 剪接来控制生长和代谢的营养物质。

Mild mitochondrial impairment enhances innate immunity and longevity through ATFS-1 and p38 signaling

轻度线粒体功能障碍可通过ATFS-1和p38信号通路增强先天免疫力和延长寿命

Dietary Restriction Extends Lifespan through Metabolic Regulation of Innate Immunity.

饮食限制通过代谢调节先天免疫力来延长寿命

Mitochondrial unfolded protein response transcription factor ATFS-1 promotes longevity in a long-lived mitochondrial mutant through activation of stress response pathways

线粒体未折叠蛋白反应转录因子ATFS-1通过激活应激反应通路促进长寿线粒体突变体的寿命

Untangling Longevity, Dauer, and Healthspan in Caenorhabditis elegans Insulin/IGF-1-Signalling

解析秀丽隐杆线虫的寿命、滞育和健康寿命：胰岛素/IGF-1信号通路

NADPH oxidase-mediated redox signaling promotes oxidative stress resistance and longevity through memo-1 in C. elegans

NADPH氧化酶介导的氧化还原信号通过秀丽隐杆线虫中的memo-1促进氧化应激抵抗和延长寿命

RNAi screening implicates a SKN-1-dependent transcriptional response in stress resistance and longevity deriving from translation inhibition.

RNAi 筛选表明，SKN-1 依赖的转录反应与抗逆性和长寿有关，这种抗逆性和长寿源于翻译抑制

Germline survival and apoptosis

生殖细胞存活与凋亡