日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

AhR activation mitigates graft-versus-host disease of the central nervous system by reducing microglial NF-κB signaling.

AhR 激活通过减少小胶质细胞 NF-κB 信号传导来减轻中枢神经系统的移植物抗宿主病

Zähringer Alexander, Morgado Inês, Erny Daniel, Ingelfinger Florian, Gawron Jana, Chatterjee Sangya, Wenger Valentin, Schmidt Dominik, Schwöbel Lennard, Adams Rachael C, Langenbach Marlene, Hartmann Alina, Osswald Natascha, Wolf Julian, Schlunck Günther, Briquez Priscilla S, Grueter Kathleen, Ruess Dietrich A, Frew Ian, Burk Ann-Cathrin, Holzmüller Verena, Grimbacher Bodo, Michonneau David, Andrieux Geoffroy, Socié Gérard, Kolter Julia, Boerries Melanie, Follo Marie, Blaeschke Franziska, Sevenich Lisa, Prinz Marco, Zeiser Robert, Vinnakota Janaki Manoja

Augmenting anti-CD19 and anti-CD22 CAR T-cell function using PD-1-CD28 checkpoint fusion proteins

利用PD-1-CD28检查点融合蛋白增强抗CD19和抗CD22 CAR T细胞的功能

Blaeschke, Franziska; Stenger, Dana; Apfelbeck, Antonia; Cadilha, Bruno L; Benmebarek, Mohamed-Reda; Mahdawi, Jasmin; Ortner, Eva; Lepenies, Mareike; Habjan, Nicola; Rataj, Felicitas; Willier, Semjon; Kaeuferle, Theresa; Majzner, Robbie G; Busch, Dirk H; Kobold, Sebastian; Feuchtinger, Tobias

Anti-CD19 CARs displayed at the surface of lentiviral vector particles promote transduction of target-expressing cells

展示在慢病毒载体颗粒表面的抗CD19 CAR可促进靶标表达细胞的转导。

Cordes, Nicole; Kolbe, Carolin; Lock, Dominik; Holzer, Tatjana; Althoff, Deborah; Schäfer, Daniel; Blaeschke, Franziska; Kotter, Bettina; Karitzky, Sandra; Rossig, Claudia; Cathomen, Toni; Feuchtinger, Tobias; Bürger, Iris; Assenmacher, Mario; Schaser, Thomas; Kaiser, Andrew D

Endogenous TCR promotes in vivo persistence of CD19-CAR-T cells compared to a CRISPR/Cas9-mediated TCR knockout CAR

与 CRISPR/Cas9 介导的 TCR 敲除 CAR 相比,内源性 TCR 可促进 CD19-CAR-T 细胞在体内的持久性。

Stenger, Dana; Stief, Tanja A; Kaeuferle, Theresa; Willier, Semjon; Rataj, Felicitas; Schober, Kilian; Vick, Binje; Lotfi, Ramin; Wagner, Beate; Grünewald, Thomas G P; Kobold, Sebastian; Busch, Dirk H; Jeremias, Irmela; Blaeschke, Franziska; Feuchtinger, Tobias

Leukemia escape in immune desert: intraocular relapse of pediatric pro-B-ALL during systemic control by CD19-CAR T cells

白血病在免疫沙漠中逃逸:CD19-CAR T 细胞全身控制期间儿童前 B 细胞急性淋巴细胞白血病发生眼内复发

Willier, Semjon; Raedler, Johannes; Blaeschke, Franziska; Stenger, Dana; Pazos Escudero, Montserrat; Jurgeleit, Florian; Grünewald, Thomas G P; Binder, Vera; Schmid, Irene; Albert, Michael H; Wolf, Armin; Feuchtinger, Tobias

Strategies of adoptive T -cell transfer to treat refractory viral infections post allogeneic stem cell transplantation

采用过继性T细胞转移治疗异基因造血干细胞移植后难治性病毒感染的策略

Kaeuferle, Theresa; Krauss, Ramona; Blaeschke, Franziska; Willier, Semjon; Feuchtinger, Tobias

Efficacy, safety and feasibility of fosaprepitant for the prevention of chemotherapy-induced nausea and vomiting in pediatric patients receiving moderately and highly emetogenic chemotherapy - results of a non-interventional observation study

福沙匹坦预防接受中度至高度致吐化疗的儿科患者化疗引起的恶心呕吐的疗效、安全性和可行性——一项非干预性观察研究的结果

Willier, Semjon; Cabanillas Stanchi, Karin Melanie; von Have, Martina; Binder, Vera; Blaeschke, Franziska; Feucht, Judith; Feuchtinger, Tobias; Döring, Michaela

Systematic identification of cancer-specific MHC-binding peptides with RAVEN

利用RAVEN系统性鉴定癌症特异性MHC结合肽

Baldauf, Michaela C; Gerke, Julia S; Kirschner, Andreas; Blaeschke, Franziska; Effenberger, Manuel; Schober, Kilian; Rubio, Rebeca Alba; Kanaseki, Takayuki; Kiran, Merve M; Dallmayer, Marlene; Musa, Julian; Akpolat, Nurset; Akatli, Ayse N; Rosman, Fernando C; Özen, Özlem; Sugita, Shintaro; Hasegawa, Tadashi; Sugimura, Haruhiko; Baumhoer, Daniel; Knott, Maximilian M L; Sannino, Giuseppina; Marchetto, Aruna; Li, Jing; Busch, Dirk H; Feuchtinger, Tobias; Ohmura, Shunya; Orth, Martin F; Thiel, Uwe; Kirchner, Thomas; Grünewald, Thomas G P

Induction of a central memory and stem cell memory phenotype in functionally active CD4(+) and CD8(+) CAR T cells produced in an automated good manufacturing practice system for the treatment of CD19(+) acute lymphoblastic leukemia

在自动化良好生产规范系统中生产的具有功能活性的 CD4(+) 和 CD8(+) CAR T 细胞中诱导中央记忆和干细胞记忆表型,用于治疗 CD19(+) 急性淋巴细胞白血病。

Blaeschke, Franziska; Stenger, Dana; Kaeuferle, Theresa; Willier, Semjon; Lotfi, Ramin; Kaiser, Andrew Didier; Assenmacher, Mario; Döring, Michaela; Feucht, Judith; Feuchtinger, Tobias

Ewing sarcoma partial regression without GvHD by chondromodulin-I/HLA-A*02:01-specific allorestricted T cell receptor transgenic T cells

软骨调节蛋白-I/HLA-A*02:01特异性同种异体限制性T细胞受体转基因T细胞可使尤文氏肉瘤部分消退,且不伴有移植物抗宿主病(GvHD)。

Thiel, Uwe; Schober, Sebastian J; Einspieler, Ingo; Kirschner, Andreas; Thiede, Melanie; Schirmer, David; Gall, Katja; Blaeschke, Franziska; Schmidt, Oxana; Jabar, Susanne; Ranft, Andreas; Alba Rubío, Rebeca; Dirksen, Uta; Grunewald, Thomas G P; Sorensen, Poul H; Richter, Günther H S; von Lüttichau, Irene Teichert; Busch, Dirk H; Burdach, Stefan E G