日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Multi-omic integration identifies broad drug resistance mechanisms and strategies to therapeutically reprogram cancer cells

多组学整合揭示了广泛的耐药机制和治疗性重编程癌细胞的策略

Mersich, Ian; Blagg, Brian S J; Ali, Aktar

The evolution of heat shock protein 90 C-terminal inhibitors: From novobiocin to potential clinical candidates

热休克蛋白90 C端抑制剂的演变:从新生霉素到潜在的临床候选药物

Jiang, Xiaosheng; Blagg, Brian S J

Attempts to Achieve Targeted Covalent Inhibition of Hsp90β

尝试实现对 Hsp90β 的靶向共价抑制

D'Amico, Terin; Reynolds, Tyelor S; Serwetnyk, Michael A; Blagg, Brian S J

The Hsp90β Isoform: An Attractive Target for Drug Development

Hsp90β亚型:药物研发的理想靶点

Chaudhury, Subhabrata; D'Amico, Terin; Blagg, Brian S J

Engineered Age-Mimetic Breast Cancer Models Reveal Differential Drug Responses in Young and Aged Microenvironments.

工程化模拟衰老的乳腺癌模型揭示了年轻和衰老微环境中不同的药物反应

Yang Jun, Hawthorne Lauren, Stack Sharon, Blagg Brian, Ali Aktar, Zorlutuna Pinar

Behavioral nudges prevent loan delinquencies at scale: A 13-million-person field experiment

行为干预可大规模预防贷款违约:一项涉及1300万人的实地实验

Kuan, Robert; Blagg, Kristin; Castleman, Benjamin L; Darolia, Rajeev; Matsudaira, Jordan D; Milkman, Katherine L; Turner, Lesley J

Glucose-regulated protein 94 (Grp94/gp96) in viral pathogenesis: Insights into its role and therapeutic potentials

葡萄糖调节蛋白94(Grp94/gp96)在病毒致病机制中的作用:对其作用和治疗潜力的深入研究

Xu, Hao; Blagg, Brian S J

Optimization of an Hsp90β-selective inhibitor via exploration of the Hsp90 N-terminal ATP-binding pocket

通过探索Hsp90 N端ATP结合口袋优化Hsp90β选择性抑制剂

Serwetnyk, Michael A; Strunden, Taddäus; Mersich, Ian; Barlow, Deborah; D'Amico, Terin; Mishra, Sanket J; Houseknecht, Karen L; Streicher, John M; Blagg, Brian S J

MaDDFLOSY(Mass Determination via Diffusion in FLow Ordered SpectroscopY) for the Determination of Diffusion-Averaged Molecular Weight of Polymers in Continuous Motion Using Benchtop NMR

利用台式核磁共振技术,通过流动有序光谱扩散法测定聚合物扩散平均分子量(MaDDFLOSY)测定连续运动聚合物的扩散平均分子量

Pointer, William; Tooley, Owen; Saib, Asad; Radmall, Rowan; Wilson, Paul; Lester, Daniel; Town, James; Blagg, Robin J; Haddleton, David

Hsp90 pan and Isoform-Selective Inhibitors as Sensitizers for Cancer Immunotherapy

Hsp90泛抑制剂和亚型选择性抑制剂作为癌症免疫疗法的增敏剂

Jia, Shiying; Maurya, Neeraj; Blagg, Brian S J; Lu, Xin