日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Roles of cGMP-dependent protein kinase I (cGKI) and PDE5 in the regulation of Ang II-induced cardiac hypertrophy and fibrosis

cGMP依赖性蛋白激酶I(cGKI)和PDE5在血管紧张素II诱导的心脏肥大和纤维化调控中的作用

Patrucco, Enrico; Domes, Katrin; Sbroggió, Mauro; Blaich, Anne; Schlossmann, Jens; Desch, Matthias; Rybalkin, Sergei D; Beavo, Joseph A; Lukowski, Robert; Hofmann, Franz

Mutation of the calmodulin binding motif IQ of the L-type Ca(v)1.2 Ca2+ channel to EQ induces dilated cardiomyopathy and death.

L 型 Ca(v)1.2 Ca2+ 通道的钙调蛋白结合基序 IQ 突变为 EQ 会导致扩张型心肌病和死亡

Blaich Anne, Pahlavan Sara, Tian Qinghai, Oberhofer Martin, Poomvanicha Montatip, Lenhardt Peter, Domes Katrin, Wegener Jörg W, Moosmang Sven, Ruppenthal Sandra, Scholz Anke, Lipp Peter, Hofmann Franz

Facilitation and Ca2+-dependent inactivation are modified by mutation of the Ca(v)1.2 channel IQ motif

Ca(v)1.2通道IQ基序的突变会改变促进作用和Ca2+依赖性失活。

Poomvanicha, Montatip; Wegener, Jörg W; Blaich, Anne; Fischer, Stefanie; Domes, Katrin; Moosmang, Sven; Hofmann, Franz