日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Current and future perspectives for structural biology at the Grenoble EPN campus: a comprehensive overview

格勒诺布尔EPN园区结构生物学的现状与未来展望:全面概述

McCarthy, Andrew A; Basu, Shibom; Bernaudat, Florent; Blakeley, Matthew P; Bowler, Matthew W; Carpentier, Philippe; Effantin, Gregory; Engilberge, Sylvain; Flot, David; Gabel, Frank; Gajdos, Lukas; Kamps, Jos J A G; Kandiah, Eaazhisai; Linares, Romain; Martel, Anne; Melnikov, Igor; Mossou, Estelle; Mueller-Dieckmann, Christoph; Nanao, Max; Nurizzo, Didier; Pernot, Petra; Popov, Alexander; Royant, Antoine; de Sanctis, Daniele; Schoehn, Guy; Talon, Romain; Tully, Mark D; Soler-Lopez, Montserrat

Counter-diffusion studies of human transthyretin: the growth of high-quality crystals for X-ray and neutron crystallography.

人类转甲状腺素的反扩散研究:用于 X 射线和中子晶体学的高质量晶体的生长

De'Ath Clare, Oliva Mizar F, Moulin Martine, Blakeley Matthew P, Haertlein Michael, Mitchell Edward P, Gavira José A, Bowler Matthew W, Forsyth V Trevor

Neutron diffraction from a microgravity-grown crystal reveals the active site hydrogens of the internal aldimine form of tryptophan synthase

利用中子衍射技术从微重力条件下生长的晶体中揭示了色氨酸合酶内部醛亚胺形式的活性位点氢原子。

Drago, Victoria N; Devos, Juliette M; Blakeley, Matthew P; Forsyth, V Trevor; Parks, Jerry M; Kovalevsky, Andrey; Mueser, Timothy C

Revealing protonation states and tracking substrate in serine hydroxymethyltransferase with room-temperature X-ray and neutron crystallography

利用室温X射线和中子晶体学揭示丝氨酸羟甲基转移酶的质子化状态并追踪底物

Drago, Victoria N; Campos, Claudia; Hooper, Mattea; Collins, Aliyah; Gerlits, Oksana; Weiss, Kevin L; Blakeley, Matthew P; Phillips, Robert S; Kovalevsky, Andrey

Covalent narlaprevir- and boceprevir-derived hybrid inhibitors of SARS-CoV-2 main protease

SARS-CoV-2主蛋白酶的共价narlaprevir和boceprevir衍生的杂合抑制剂

Kneller, Daniel W; Li, Hui; Phillips, Gwyndalyn; Weiss, Kevin L; Zhang, Qiu; Arnould, Mark A; Jonsson, Colleen B; Surendranathan, Surekha; Parvathareddy, Jyothi; Blakeley, Matthew P; Coates, Leighton; Louis, John M; Bonnesen, Peter V; Kovalevsky, Andrey

Neutron crystallography reveals mechanisms used by Pseudomonas aeruginosa for host-cell binding

中子晶体学揭示了铜绿假单胞菌与宿主细胞结合的机制

Gajdos, Lukas; Blakeley, Matthew P; Haertlein, Michael; Forsyth, V Trevor; Devos, Juliette M; Imberty, Anne

An N⋯H⋯N low-barrier hydrogen bond preorganizes the catalytic site of aspartate aminotransferase to facilitate the second half-reaction

N⋯H⋯N 低势垒氢键预先组织天冬氨酸氨基转移酶的催化位点,以促进第二半反应。

Drago, Victoria N; Dajnowicz, Steven; Parks, Jerry M; Blakeley, Matthew P; Keen, David A; Coquelle, Nicolas; Weiss, Kevin L; Gerlits, Oksana; Kovalevsky, Andrey; Mueser, Timothy C

Microgravity crystallization of perdeuterated tryptophan synthase for neutron diffraction

利用中子衍射技术在微重力条件下结晶全氘代色氨酸合酶

Drago, Victoria N; Devos, Juliette M; Blakeley, Matthew P; Forsyth, V Trevor; Kovalevsky, Andrey Y; Schall, Constance A; Mueser, Timothy C

Joint neutron/X-ray crystal structure of a mechanistically relevant complex of perdeuterated urate oxidase and simulations provide insight into the hydration step of catalysis

全氘代尿酸氧化酶相关复合物的中子/X射线联合晶体结构及模拟结果,为催化过程中的水合步骤提供了深入的见解。

McGregor, Lindsay; Földes, Tamás; Bui, Soi; Moulin, Martine; Coquelle, Nicolas; Blakeley, Matthew P; Rosta, Edina; Steiner, Roberto A

Neutron structures of Leishmania mexicana triosephosphate isomerase in complex with reaction-intermediate mimics shed light on the proton-shuttling steps

墨西哥利什曼原虫磷酸丙糖异构酶与反应中间体类似物复合物的中子结构揭示了质子穿梭步骤

Kelpšas, Vinardas; Caldararu, Octav; Blakeley, Matthew P; Coquelle, Nicolas; Wierenga, Rikkert K; Ryde, Ulf; von Wachenfeldt, Claes; Oksanen, Esko