文献库，生知库 | 链接生命科学的每一步

日期影响因子

Evaluation of pyrrolidine and pyrazolone derivatives as inhibitors of trypanosomal phosphodiesterase B1 (TbrPDEB1)

吡咯烷和吡唑酮衍生物作为锥虫磷酸二酯酶B1 (TbrPDEB1) 抑制剂的评价

期刊:Tetrahedron Letters

影响因子:1.5

doi:10.1016/j.tetlet.2015.04.061

Amata, Emanuele; Bland, Nicholas D; Campbell, Robert K; Pollastri, Michael P

发表日期：2015

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Repurposing human PDE4 inhibitors for neglected tropical diseases. Evaluation of analogs of the human PDE4 inhibitor GSK-256066 as inhibitors of PDEB1 of Trypanosoma brucei

将人类PDE4抑制剂用于被忽视的热带病。评估人类PDE4抑制剂GSK-256066类似物作为布氏锥虫PDEB1抑制剂的活性。

doi:10.1111/cbdd.12443

Ochiana, Stefan O; Bland, Nicholas D; Settimo, Luca; Campbell, Robert K; Pollastri, Michael P

发表日期：2015

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Repurposing human PDE4 inhibitors for neglected tropical diseases: design, synthesis and evaluation of cilomilast analogues as Trypanosoma brucei PDEB1 inhibitors

将人类PDE4抑制剂用于被忽视的热带病：设计、合成和评价cilomilast类似物作为布氏锥虫PDEB1抑制剂

期刊:Bioorganic & Medicinal Chemistry Letters

影响因子:2.2

doi:10.1016/j.bmcl.2014.07.063

Amata, Emanuele; Bland, Nicholas D; Hoyt, Charles T; Settimo, Luca; Campbell, Robert K; Pollastri, Michael P

发表日期：2014

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Synthesis and assessment of catechol diether compounds as inhibitors of trypanosomal phosphodiesterase B1 (TbrPDEB1)

合成和评价儿茶酚二醚化合物作为锥虫磷酸二酯酶B1（TbrPDEB1）抑制剂

期刊:Bioorganic & Medicinal Chemistry Letters

影响因子:2.2

doi:10.1016/j.bmcl.2013.08.057

Woodring, Jennifer L; Bland, Nicholas D; Ochiana, Stefan O; Campbell, Robert K; Pollastri, Michael P

发表日期：2013

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Synthesis and evaluation of human phosphodiesterases (PDE) 5 inhibitor analogs as trypanosomal PDE inhibitors. Part 1. Sildenafil analogs

人磷酸二酯酶 (PDE) 5 抑制剂类似物作为锥虫 PDE 抑制剂的合成与评价。第一部分：西地那非类似物

期刊:Bioorganic & Medicinal Chemistry Letters

影响因子:2.2

doi:10.1016/j.bmcl.2012.01.119

Wang, Cuihua; Ashton, Trent D; Gustafson, Alden; Bland, Nicholas D; Ochiana, Stefan O; Campbell, Robert K; Pollastri, Michael P

发表日期：2012

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Synthesis and evaluation of human phosphodiesterases (PDE) 5 inhibitor analogs as trypanosomal PDE inhibitors. Part 2. Tadalafil analogs

人磷酸二酯酶 (PDE) 5 抑制剂类似物作为锥虫 PDE 抑制剂的合成与评价。第二部分：他达拉非类似物

期刊:Bioorganic & Medicinal Chemistry Letters

影响因子:2.2

doi:10.1016/j.bmcl.2012.01.118

Ochiana, Stefan O; Gustafson, Alden; Bland, Nicholas D; Wang, Cuihua; Russo, Michael J; Campbell, Robert K; Pollastri, Michael P

发表日期：2012

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Crystal structure of Leishmania major oligopeptidase B gives insight into the enzymatic properties of a trypanosomatid virulence factor.

利什曼原虫寡肽酶 B 的晶体结构揭示了锥虫毒力因子的酶学特性

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1074/jbc.M110.156679

McLuskey Karen, Paterson Neil G, Bland Nicholas D, Isaacs Neil W, Mottram Jeremy C

发表日期：2010

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Drosophila melanogaster NEP2 is a new soluble member of the neprilysin family of endopeptidases with implications for reproduction and renal function

果蝇NEP2是脑啡肽酶家族中一种新的可溶性内肽酶成员，与生殖和肾功能相关。

期刊:Biochemical Journal

影响因子:4.3

doi:10.1042/BJ20041753

Thomas, Josie E; Rylett, Caroline M; Carhan, Ahmet; Bland, Nicholas D; Bingham, Richard J; Shirras, Alan D; Turner, Anthony J; Isaac, R Elwyn

发表日期：2005

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