日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Purified Diets Lacking Fermentable Fiber Reduce Microbial Diversity, Alter Epithelial Transcriptome, and Exacerbate Colitis

缺乏可发酵纤维的纯化饮食会降低微生物多样性,改变上皮细胞转录组,并加剧结肠炎。

Thomas, Emma Griffith; Ortutu, Beulah Favour; Watson, Jacob Connor; Ong, Ethan; Blankley, Kaitlyn Eileen; Meaurio Martin, Angela; Shankar, Smriti; Zhang, Dongmei; Boland, Devon Joseph; Wu, Chia-Shan

A new strategy for hit generation: Novel in cellulo active inhibitors of CYP121A1 from Mycobacterium tuberculosis via a combined X-ray crystallographic and phenotypic screening approach (XP screen)

生成有效化合物的新策略:通过结合 X 射线晶体学和表型筛选方法(XP 筛选)寻找结核分枝杆菌 CYP121A1 的新型纤维素活性抑制剂

Martyn Frederickson, Irwin R Selvam, Dimitrios Evangelopoulos, Kirsty J McLean, Mona M Katariya, Richard B Tunnicliffe, Bethany Campbell, Madeline E Kavanagh, Sitthivut Charoensutthivarakul, Richard T Blankley, Colin W Levy, Luiz Pedro S de Carvalho, David Leys, Andrew W Munro, Anthony G Coyne, Chri

Lessons learned: Retrospective assessment of outcomes and management of patients with advanced HIV disease in a semi-urban polyclinic in Epworth, Zimbabwe

经验教训:对津巴布韦埃普沃斯半城市综合诊所晚期艾滋病患者的治疗结果和管理进行回顾性评估

Blankley, Simon; Gashu, Tadele; Ahmad, Bilal; Belaye, Abi Kebra; Ringtho, Lucia; Mesic, Anita; Zizhou, Simukai; Casas, Esther C

Model of care and risk factors for poor outcomes in patients on multi-drug resistant tuberculosis treatment at two facilities in eSwatini (formerly Swaziland), 2011-2013

2011-2013年斯威士兰(原斯威士兰)两家医疗机构多重耐药结核病患者治疗模式及不良预后风险因素分析

Verdecchia, M; Keus, K; Blankley, S; Vambe, D; Ssonko, C; Piening, T; Casas, E C

A 380-gene meta-signature of active tuberculosis compared with healthy controls

与健康对照组相比,活动性结核病的380基因荟萃特征分析

Blankley, Simon; Graham, Christine M; Levin, Joe; Turner, Jacob; Berry, Matthew P R; Bloom, Chloe I; Xu, Zhaohui; Pascual, Virgina; Banchereau, Jacques; Chaussabel, Damien; Breen, Ronan; Santis, George; Blankenship, Derek M; Lipman, Marc; O'Garra, Anne

Differential Production of Type I IFN Determines the Reciprocal Levels of IL-10 and Proinflammatory Cytokines Produced by C57BL/6 and BALB/c Macrophages

型干扰素的差异产生决定了 C57BL/6 和 BALB/c 巨噬细胞产生的 IL-10 和促炎细胞因子的相互水平

Ashleigh Howes, Christina Taubert, Simon Blankley, Natasha Spink, Xuemei Wu, Christine M Graham, Jiawen Zhao, Margarida Saraiva, Paola Ricciardi-Castagnoli, Gregory J Bancroft, Anne O'Garra

The Transcriptional Signature of Active Tuberculosis Reflects Symptom Status in Extra-Pulmonary and Pulmonary Tuberculosis

活动性结核病的转录特征反映了肺外结核病和肺结核病的症状状态

Blankley, Simon; Graham, Christine M; Turner, Jacob; Berry, Matthew P R; Bloom, Chloe I; Xu, Zhaohui; Pascual, Virginia; Banchereau, Jacques; Chaussabel, Damien; Breen, Ronan; Santis, George; Blankenship, Derek M; Lipman, Marc; O'Garra, Anne

Analysis of Transcriptional Signatures in Response to Listeria monocytogenes Infection Reveals Temporal Changes That Result from Type I Interferon Signaling

对单核细胞增生李斯特菌感染反应的转录特征分析揭示了由I型干扰素信号传导引起的时序变化

Pitt, Jonathan M; Blankley, Simon; Potempa, Krzysztof; Graham, Christine M; Moreira-Teixeira, Lucia; McNab, Finlay W; Howes, Ashleigh; Stavropoulos, Evangelos; Pascual, Virginia; Banchereau, Jacques; Chaussabel, Damien; O'Garra, Anne

The Blood Transcriptome of Experimental Melioidosis Reflects Disease Severity and Shows Considerable Similarity with the Human Disease

实验性类鼻疽的血液转录组反映了疾病的严重程度,并与人类疾病表现出相当大的相似性。

Conejero, Laura; Potempa, Krzysztof; Graham, Christine M; Spink, Natasha; Blankley, Simon; Salguero, Francisco J; Pankla-Sranujit, Rungnapa; Khaenam, Prasong; Banchereau, Jacques F; Pascual, Virginia; Chaussabel, Damien; Lertmemongkolchai, Ganjana; O'Garra, Anne; Bancroft, Gregory J

Identification of the key differential transcriptional responses of human whole blood following TLR2 or TLR4 ligation in-vitro

体外TLR2或TLR4配体结合后人全血关键差异转录反应的鉴定

Blankley, Simon; Graham, Christine M; Howes, Ashleigh; Bloom, Chloe I; Berry, Matthew P R; Chaussabel, Damien; Pascual, Virginia; Banchereau, Jacques; Lipman, Marc; O'Garra, Anne