日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Myocardial PKG1α dysregulation contributes to ventricular tachycardia pathogenesis in type 2 diabetes and metabolic syndrome

心肌PKG1α失调与2型糖尿病和代谢综合征中室性心动过速的发病机制有关。

Cao, Xuehong; Zhang, Yali; Tripp, Audrey; Steinhauer, Rachel; Liu, Pei-Wen; Aronovitz, Mark J; Martin, Greg L; Wang, Bo; Alissa, Abdullah; Aljuaid, Mossab; Ho, Justin; Phan, Tina; Madias, Christopher; Blanton, Robert M; Galper, Jonas B

T cell-derived IFNγ instructs ECM crosslinking by cardiac fibroblasts through LOXL3 in experimental cardiometabolic HFpEF.

在实验性心脏代谢性 HFpEF 中,T 细胞衍生的 IFNγ 通过 LOXL3 指导心脏成纤维细胞进行 ECM 交联。

Emig Ramona, Robbe Zachary, Kley Celina, Smolgovsky Sasha, Travers Joshua G, Blanton Robert M, McKinsey Timothy A, Black Lauren D, Alcaide Pilar

Obesity and Heart Failure: Mechanistic Insights and the Regulatory Role of MicroRNAs

肥胖与心力衰竭:机制解析及microRNA的调控作用

Sahu, Parul; Bestepe, Furkan; Vehbi, Sezan; Ghanem, George F; Blanton, Robert M; Icli, Basak

Myocardial cGMP-PKG1α dysregulation contributes to VT pathogenesis in type II diabetes and metabolic syndrome

心肌cGMP-PKG1α失调与II型糖尿病和代谢综合征患者的室性心动过速发病机制有关。

Cao, Xuehong; Zhang, Yali; Tripp, Audrey; Steinhauer, Rachel; Liu, Pei-Wen; Aronovitz, Mark J; Martin, Greg L; Wang, Bo; Alissa, Abdullah; Aljuaid, Mossab; Ho, Justin; Phan, Tina; Madias, Christopher; Blanton, Robert M; Galper, Jonas B

Beta Testing New Roles of Cyclic Guanosine Monophosphate in Cardiac Myocyte Contractility

环磷酸鸟苷在心肌细胞收缩性中的新作用的Beta测试

Blanton, Robert M

The mitochondrial regulator PGC1α is induced by cGMP-PKG signaling and mediates the protective effects of phosphodiesterase 5 inhibition in heart failure

线粒体调节因子PGC1α受cGMP-PKG信号通路诱导,并介导磷酸二酯酶5抑制剂在心力衰竭中的保护作用。

Zhu, Guangshuo; Ueda, Kazutaka; Hashimoto, Masaki; Zhang, Manling; Sasaki, Masayuki; Kariya, Taro; Sasaki, Hideyuki; Kaludercic, Nina; Lee, Dong-Ik; Bedja, Djahida; Gabrielson, Matthew; Yuan, Yuan; Paolocci, Nazareno; Blanton, Robert M; Karas, Richard H; Mendelsohn, Michael E; O'Rourke, Brian; Kass, David A; Takimoto, Eiki

Isolevuglandin-Modified Cardiac Proteins Drive CD4+ T-Cell Activation in the Heart and Promote Cardiac Dysfunction

异戊二酸修饰的心脏蛋白驱动心脏中CD4+ T细胞活化并促进心脏功能障碍

Ngwenyama, Njabulo; Kirabo, Annet; Aronovitz, Mark; Velázquez, Francisco; Carrillo-Salinas, Francisco; Salvador, Ane M; Nevers, Tania; Amarnath, Venkataraman; Tai, Albert; Blanton, Robert M; Harrison, David G; Alcaide, Pilar

Endothelial Pannexin 1 Regulates Cardiac Response to Myocardial Infarction

内皮细胞Pannexin 1调节心肌梗死后的心脏反应

Good, Miranda E; Young, Alexander P; Wolpe, Abigail G; Ma, Manxiu; Hall, Philip J; Duffy, Colleen K; Aronovitz, Mark J; Martin, Gregory L; Blanton, Robert M; Leitinger, Norbert; Johnstone, Scott R; Wolf, Matthew J; Isakson, Brant E

CRD-733, a Novel PDE9 (Phosphodiesterase 9) Inhibitor, Reverses Pressure Overload-Induced Heart Failure

CRD-733 是一种新型 PDE9(磷酸二酯酶 9)抑制剂,可逆转压力超负荷诱发的心力衰竭。

Richards, Daniel A; Aronovitz, Mark J; Liu, Peiwen; Martin, Gregory L; Tam, Kelly; Pande, Suchita; Karas, Richard H; Bloomfield, Daniel M; Mendelsohn, Michael E; Blanton, Robert M

Phosphodiesterase 9 Inhibition in Models of Heart Failure With Preserved Left Ventricular Ejection Fraction: Should We Focus on the Positive or Negative?

在左心室射血分数保留的心力衰竭模型中,磷酸二酯酶 9 抑制剂的作用:我们应该关注其积极作用还是消极作用?

Blanton, Robert M