日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

M4205 (IDRX-42) Is a Highly Selective and Potent Inhibitor of Relevant Oncogenic Driver and Resistance Variants of KIT in Cancer.

M4205 (IDRX-42) 是一种对癌症中 KIT 相关致癌驱动因子和耐药变体具有高度选择性和强效抑制作用的抑制剂

期刊:Molecular Cancer Therapeutics
影响因子:5.5
doi:10.1158/1535-7163.MCT-24-0699
Esdar Christina, Linde Nina, Blum Andreas, Schieferstein Hanno, Drechsler Christine, Sherbetjian Eva, Petersson Carl, Ross Edith, Leuthner Birgitta, Grädler Ulrich, Dorsch Dieter, Blaukat Andree
肿瘤
肿瘤免疫
发表日期：2025
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The Preclinical Pharmacology of Tepotinib-A Highly Selective MET Inhibitor with Activity in Tumors Harboring MET Alterations

Tepotinib 的临床前药理学研究——一种对携带 MET 改变的肿瘤具有活性的高选择性 MET 抑制剂

期刊:Molecular Cancer Therapeutics
影响因子:5.5
doi:10.1158/1535-7163.MCT-22-0537
Albers, Joachim; Friese-Hamim, Manja; Clark, Anderson; Schadt, Oliver; Walter-Bausch, Gina; Stroh, Christopher; Johne, Andreas; Karachaliou, Niki; Blaukat, Andree
肿瘤
MET
肿瘤免疫
发表日期：2023
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SHP2 Inhibition Influences Therapeutic Response to Tepotinib in Tumors with MET Alterations

SHP2抑制影响MET改变肿瘤对替泊替尼的治疗反应

期刊:iScience
影响因子:4.1
doi:10.1016/j.isci.2020.101832
Pudelko, Linda; Jaehrling, Frank; Reusch, Christof; Vitri, Sanziago; Stroh, Christopher; Linde, Nina; Sanderson, Michael P; Musch, Doreen; Lebrun, Catherine Jorand; Keil, Marina; Esdar, Christina; Blaukat, Andree; Rosell, Rafael; Schumacher, Karl Maria; Karachaliou, Niki
肿瘤
MET
肿瘤免疫
发表日期：2020
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Overcoming hypoxia-induced tumor radioresistance in non-small cell lung cancer by targeting DNA-dependent protein kinase in combination with carbon ion irradiation

通过靶向DNA依赖性蛋白激酶联合碳离子照射克服非小细胞肺癌中缺氧诱导的肿瘤放射抗性

期刊:Radiation Oncology
影响因子:3.2
doi:10.1186/s13014-017-0939-0
Klein, Carmen; Dokic, Ivana; Mairani, Andrea; Mein, Stewart; Brons, Stephan; Häring, Peter; Haberer, Thomas; Jäkel, Oliver; Zimmermann, Astrid; Zenke, Frank; Blaukat, Andree; Debus, Jürgen; Abdollahi, Amir
肺癌
肿瘤
肿瘤免疫
信号转导
细胞生物学
发表日期：2017
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Nephrocystin-4 regulates Pyk2-induced tyrosine phosphorylation of nephrocystin-1 to control targeting to monocilia

肾囊蛋白-4通过调节Pyk2诱导的肾囊蛋白-1酪氨酸磷酸化来控制其向单纤毛的靶向定位。

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.M110.165464
Liebau, Max C; Höpker, Katja; Müller, Roman U; Schmedding, Ingolf; Zank, Sibylle; Schairer, Benjamin; Fabretti, Francesca; Höhne, Martin; Bartram, Malte P; Dafinger, Claudia; Hackl, Matthias; Burst, Volker; Habbig, Sandra; Zentgraf, Hanswalter; Blaukat, Andree; Walz, Gerd; Benzing, Thomas; Schermer, Bernhard
信号转导
磷酸化
发表日期：2011
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Phosphorylation and regulation of a G protein-coupled receptor by protein kinase CK2

蛋白激酶CK2对G蛋白偶联受体的磷酸化和调控

期刊:Journal of Cell Biology
影响因子:6.4
doi:10.1083/jcb.200610018
Torrecilla, Ignacio; Spragg, Elizabeth J; Poulin, Benoit; McWilliams, Phillip J; Mistry, Sharad C; Blaukat, Andree; Tobin, Andrew B
信号转导
磷酸化
发表日期：2007
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Phosphorylation by casein kinase 2 induces PACS-1 binding of nephrocystin and targeting to cilia

酪蛋白激酶2的磷酸化作用诱导肾囊蛋白与PACS-1结合，并使其靶向纤毛。

期刊:EMBO Journal
影响因子:8.3
doi:10.1038/sj.emboj.7600885
Schermer, Bernhard; Höpker, Katja; Omran, Heymut; Ghenoiu, Cristina; Fliegauf, Manfred; Fekete, Andrea; Horvath, Judit; Köttgen, Michael; Hackl, Matthias; Zschiedrich, Stefan; Huber, Tobias B; Kramer-Zucker, Albrecht; Zentgraf, Hanswalter; Blaukat, Andree; Walz, Gerd; Benzing, Thomas
信号转导
磷酸化
发表日期：2005
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