An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/- mice
mTOR抑制剂可减少Pten+/-小鼠的肿瘤形成并使p70/S6激酶活性恢复正常。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.171060098
Podsypanina, K; Lee, R T; Politis, C; Hennessy, I; Crane, A; Puc, J; Neshat, M; Wang, H; Yang, L; Gibbons, J; Frost, P; Dreisbach, V; Blenis, J; Gaciong, Z; Fisher, P; Sawyers, C; Hedrick-Ellenson, L; Parsons, R