日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A Novel Small Molecule Allosteric Inhibitor of IL-17A from a DNA-Encoded Library

从DNA编码库中筛选出一种新型IL-17A小分子变构抑制剂

Milla, Marcos E; Blevitt, Jonathan M; Goldberg, Steven D; Armstrong, Anthony A; Blain, Katherine Y; Herman, Krystal L; Liu, Annie X; Luna, Rosa; Milligan, Cynthia M; Patrick, Aaron N; Steele, Ruth A; Bembenek, Scott D; Centrella, Paolo; Clark, Matthew A; Cuozzo, John W; Disch, Jeremy S; Domingo, Derrick; Hunt, Avery; Hupp, Christoper D; Keefe, Anthony D; Luo, Jinquan; Mirzadegan, Tara; Nelen, Marina I; Resnicow, Daniel I; Sigel, Eric A; Soutter, Holly H; Troast, Dawn M; Xue, Xiaohua; Yi, Fang; Zhang, Ying; Jackson, Paul F; Edwards, James P; Lumb, Kevin J

High-throughput phenotypic screen identifies a new family of potent anti-amoebic compounds

高通量表型筛选鉴定出一类新型强效抗阿米巴化合物

Sauvey, Conall; Meewan, Ittipat; Ehrenkaufer, Gretchen; Blevitt, Jonathan; Jackson, Paul; Abagyan, Ruben

Coupling to Gq Signaling Is Required for Cardioprotection by an Alpha-1A-Adrenergic Receptor Agonist

α1A肾上腺素能受体激动剂发挥心脏保护作用需要与Gq信号通路偶联

Myagmar, Bat-Erdene; Ismaili, Taylor; Swigart, Philip M; Raghunathan, Anaha; Baker, Anthony J; Sahdeo, Sunil; Blevitt, Jonathan M; Milla, Marcos E; Simpson, Paul C

RORγt and RORα signature genes in human Th17 cells

人类 Th17 细胞中的 RORγt 和 RORα 特征基因

Glenda Castro, Xuejun Liu, Karen Ngo, Aimee De Leon-Tabaldo, Shanrong Zhao, Rosa Luna-Roman, Jingxue Yu, Tinghua Cao, Robert Kuhn, Patrick Wilkinson, Krystal Herman, Marina I Nelen, Jonathan Blevitt, Xiaohua Xue, Anne Fourie, Wai-Ping Fung-Leung

A Single Amino Acid Difference between Mouse and Human 5-Lipoxygenase Activating Protein (FLAP) Explains the Speciation and Differential Pharmacology of Novel FLAP Inhibitors

小鼠和人类5-脂氧合酶激活蛋白(FLAP)之间单个氨基酸的差异解释了新型FLAP抑制剂的种类和差异药理学特性

Jonathan M Blevitt ,Michael D Hack ,Krystal Herman ,Leon Chang ,John M Keith ,Tara Mirzadegan ,Navin L Rao ,Alec D Lebsack ,Marcos E Milla

Structural analysis of the p62 complex, an assembly of O-linked glycoproteins that localizes near the central gated channel of the nuclear pore complex

p62复合物的结构分析表明,p62复合物是由O-连接糖蛋白组成的复合物,定位于核孔复合物的中央门控通道附近。

Guan, T; Müller, S; Klier, G; Panté, N; Blevitt, J M; Haner, M; Paschal, B; Aebi, U; Gerace, L

The alpha-helical rod domain of human lamins A and C contains a chromatin binding site

人核纤层蛋白A和C的α螺旋杆状结构域包含染色质结合位点

Glass, C A; Glass, J R; Taniura, H; Hasel, K W; Blevitt, J M; Gerace, L

O-linked glycoproteins of the nuclear pore complex interact with a cytosolic factor required for nuclear protein import

核孔复合体的O-连接糖蛋白与胞质因子相互作用,该因子是核蛋白输入所必需的。

Sterne-Marr, R; Blevitt, J M; Gerace, L