日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Loss of ALK4 promotes cancer progression through regulating TGF-β receptor N-glycosylation

ALK4 的缺失通过调节 TGF-β 受体 N-糖基化促进癌症进展。

Zhang, Manqi; Chen, Jian; Leupold, Mary C; Guo, Jennifer; Shen, Xiangfeng; Shirley, Carl A; Khella, Christen A; Mehta, Rushabh N; O'Brien, Edward T; Gatza, Michael L; Blobe, Gerard C

NRP1 interacts with endoglin and VEGFR2 to modulate VEGF signaling and endothelial cell sprouting

NRP1与内皮糖蛋白和VEGFR2相互作用,调节VEGF信号传导和内皮细胞出芽。

Swati Sharma ,Marcelo Ehrlich ,Manqi Zhang ,Gerard C Blobe ,Yoav I Henis

Assessing the utility of molecular diagnostic classification for cancers of unknown primary

评估分子诊断分类在原发灶不明癌症中的应用价值

Moore, Elle C; Blobe, Gerard C; DeVito, Nicholas C; Hanks, Brent A; Harrison, Michael R; Hoimes, Christopher J; Jia, Jingquan; Morse, Michael A; Jayaprakasan, Parvathy; MacKelfresh, Andrew; Mulder, Hillary; Hockenberry, Adam J; Zander, Alia; Stumpe, Martin C; Michuda, Jackson; Beauchamp, Kyle A; Perakslis, Eric; Taxter, Timothy; George, Daniel J

TGF-β superfamily co-receptors in cancer

TGF-β超家族共受体在癌症中的作用

Pawlak, John B; Blobe, Gerard C

Cabozantinib and Panitumumab for RAS Wild-Type Metastatic Colorectal Cancer

卡博替尼联合帕尼单抗治疗 RAS 野生型转移性结直肠癌

Strickler, John H; Rushing, Christel N; Uronis, Hope E; Morse, Michael A; Niedzwiecki, Donna; Blobe, Gerard C; Moyer, Ashley N; Bolch, Emily; Webb, Renee; Haley, Sherri; Hatch, Ace J; Altomare, Ivy P; Sherrill, Gary B; Chang, David Z; Wells, James L; Hsu, S David; Jia, Jingquan; Zafar, S Yousuf; Nixon, Andrew B; Hurwitz, Herbert I

ALK1 regulates the internalization of endoglin and the type III TGF-β receptor

ALK1 调节内皮糖蛋白和 III 型 TGF-β 受体的内吞作用

Keren Tazat ,Leslie Pomeraniec-Abudy ,Melissa Hector-Greene ,Szabina Szófia Szilágyi ,Swati Sharma ,Elise M Cai ,Armando L Corona ,Marcelo Ehrlich ,Gerard C Blobe ,Yoav I Henis

Increased type III TGF-β receptor shedding decreases tumorigenesis through induction of epithelial-to-mesenchymal transition

III 型 TGF-β 受体脱落增加可诱导上皮-间质转化从而降低肿瘤发生

Jennifer J Huang, Armando L Corona, Brian P Dunn, Elise M Cai, Jesse N Prakken, Gerard C Blobe

A phase Ib study of the combination regorafenib with PF-03446962 in patients with refractory metastatic colorectal cancer (REGAL-1 trial)

一项针对难治性转移性结直肠癌患者的瑞戈非尼联合PF-03446962的Ib期研究(REGAL-1试验)

Clarke, Jeffrey Melson; Blobe, Gerard C; Strickler, John H; Uronis, Hope Elizabeth; Zafar, S Yousuf; Morse, Michael; Dropkin, Evan; Howard, Leigh; O'Neill, Margot; Rushing, Christel N; Niedzwiecki, Donna; Watson, Hollie; Bolch, Emily; Arrowood, Christy; Liu, Yingmiao; Nixon, Andrew B; Hurwitz, Herbert I

Stromal Fibroblasts Mediate Anti-PD-1 Resistance via MMP-9 and Dictate TGFβ Inhibitor Sequencing in Melanoma

基质成纤维细胞通过 MMP-9 介导抗 PD-1 耐药性,并决定黑色素瘤中 TGFβ 抑制剂的治疗顺序。

Fei Zhao ,Kathy Evans ,Christine Xiao ,Nicholas DeVito ,Balamayooran Theivanthiran ,Alisha Holtzhausen ,Peter J Siska ,Gerard C Blobe ,Brent A Hanks

Endoglin interacts with VEGFR2 to promote angiogenesis

Endoglin 与 VEGFR2 相互作用促进血管生成

Hongyu Tian, Jennifer J Huang, Christelle Golzio, Xia Gao, Melissa Hector-Greene, Nicholas Katsanis, Gerard C Blobe