日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

A damaging mutation in COL6A3 alters the mechanobiologic response of chondrocytes derived from human induced pluripotent stem cells

COL6A3基因的有害突变会改变人诱导多能干细胞来源的软骨细胞的力学生物学反应。

期刊:Stem Cell Research & Therapy
影响因子:7.3
doi:10.1186/s13287-026-04940-7
Harissa, Zainab; Bloks, Niek; Steward, Nancy; Tufa, Sara F; Keene, Douglas R; Ramos, Yolande F M; Meulenbelt, Ingrid; Guilak, Farshid
细胞生物学
发育与干细胞
COL
干细胞
发表日期：2026
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Farnesoid x Receptor Deficiency Promotes Hepatocytic Injury in Cyp2c70-Deficient Mice With a Human-Like Bile Acid Composition

法尼醇X受体缺陷会促进Cyp2c70缺陷小鼠（其胆汁酸组成与人类相似）的肝细胞损伤。

期刊:Liver International
影响因子:5.2
doi:10.1111/liv.70632
de Vries, Hilde D; Li, Jinxiao; Ustyantsev, Kirill; Hovingh, Milaine V; Mulder, Niels L; Havinga, Rick; Palmiotti, Anna; de Bruyn, Krisztina; Attema, Brecht; Weersing, Ellen; Thomas, Rachel E; Bloks, Vincent W; Berezikov, Eugene; van Faassen, Martijn; Verkade, Henkjan J; de Boer, Jan Freark; Kuipers, Folkert
信号转导
细胞生物学
Human
发表日期：2026
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Loss of Early Growth Response Protein 1 in the Liver Leads to Hepatic Lipid Accumulation Driven by an Imbalance Between Fatty Acid β-Oxidation and Oxidative Phosphorylation.

肝脏中早期生长反应蛋白 1 的缺失导致肝脏脂质积累，这是由于脂肪酸 β-氧化和氧化磷酸化之间的不平衡所致。

期刊:Gastro Hep Advances
影响因子:
doi:10.1016/j.gastha.2026.100881
Verzijl Cristy R C, Struik Dicky, Gerding Albert, Eilers Roos E, Thomas Rachel E, Koster Mirjam, Langelaar-Makkinje Miriam, Smit Marieke, Huijkman Nicolette, Havinga Rick, Kloosterhuis Niels, Bloks Vincent W, Wolters Justina C, de Boer Jan Freark, van de Sluis Bart, Bakker Barbara M, Jonker Johan W
磷酸化
发表日期：2026
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An International Longitudinal Natural History Study of Patients With Danon Disease: Unique Cardiac Trajectories Identified Based on Sex and Heart Failure Outcomes

一项针对达农病患者的国际纵向自然史研究：基于性别和心力衰竭结局识别出独特的心脏轨迹

期刊:Journal of the American Heart Association
影响因子:5.3
doi:10.1161/JAHA.124.038394
Hong, Kimberly N; Eshraghian, Emily; Khedro, Tarek; Argirò, Alessia; Attias, Jennifer; Storm, Garrett; Tsotras, Melina; Bloks, Tanner; Jackson, Isaiah; Ahmad, Elijah; Graw, Sharon; Mestroni, Luisa; Bui, Quan M; Schwartz, Jonathan; Turner, Stuart; Adler, Eric D; Taylor, Matthew
心力衰竭
心血管
发表日期：2025
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Elevated plasma bile acids coincide with cardiac stress and inflammation in young Cyp2c70(-/-) mice

在年轻的Cyp2c70(-/-)小鼠中，血浆胆汁酸水平升高与心脏应激和炎症同时发生。

期刊:Pediatric Research
影响因子:3.1
doi:10.1038/s41390-024-03596-4
de Vries, Hilde D; Eijgenraam, Tim R; Bloks, Vincent W; Mulder, Niels L; van Zutphen, Tim; Silljé, Herman H W; Kuipers, Folkert; de Boer, Jan Freark
炎症/感染
炎症
发表日期：2025
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Stiff Knee Gait After Stroke: The Potential Compensatory Role of Mid-Swing Rectus Femoris Activity

中风后膝关节僵硬步态：股直肌摆动中期活动的潜在代偿作用

期刊:Case Reports in Neurological Medicine
影响因子:0.9
doi:10.1155/crnm/7703081
van Oorschot, Wieneke; Bloks, Bente; Kamphuis, Jip; Pieterse, Allan; Geurts, Alexander; Keijsers, Noël; Nonnekes, Jorik
中风
心血管
发表日期：2025
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A Damaging COL6A3 Variant Alters the MIR31HG-Regulated Response of Chondrocytes in Neocartilage Organoids to Hyperphysiologic Mechanical Loading

致病性 COL6A3 变异体改变了新生软骨类器官中软骨细胞对超生理机械负荷的 MIR31HG 调控反应。

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202400720
Bloks, Niek Gc; Harissa, Zainab; Mazzini, Giorgia; Adkar, Shaunak S; Dicks, Amanda R; Hajmousa, Ghazaleh; Steward, Nancy; Koning, Roman I; Mulder, Aat; de Koning, Berend B R; Kloppenburg, Margreet; de Almeida, Rodrigo Coutinho; Ramos, Yolande Fm; Guilak, Farshid; Meulenbelt, Ingrid
3D/类器官
信号转导
细胞生物学
COL
发表日期：2024
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Plantar pressure in relation to hindfoot varus in people with unilateral upper motor neuron syndrome

单侧上运动神经元综合征患者的足底压力与后足内翻的关系

期刊:Journal of Foot and Ankle Research
影响因子:2.2
doi:10.1002/jfa2.12041
Bloks, Bente E; Wilders, Lise M; Louwerens, Jan Willem K; Geurts, Alexander C; Nonnekes, Jorik; Keijsers, Noël L W
神经科学
发表日期：2024
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The role of DNA methylation in chondrogenesis of human iPSCs as a stable marker of cartilage quality

DNA 甲基化在人类 iPSC 软骨形成中的作用作为软骨质量的稳定标志

期刊:Clinical Epigenetics
影响因子:
doi:10.1186/s13148-024-01759-y
Ghazaleh Hajmousa #, Rodrigo Coutinho de Almeida #, Niek Bloks #, Alejandro Rodríguez Ruiz, Marga Bouma, Roderick Slieker, Thomas B Kuipers, Rob G H H Nelissen, Keita Ito, Christian Freund, Yolande F M Ramos, Ingrid Meulenbelt
表观遗传
DNA甲基化
发表日期：2024
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Hyper-physiologic mechanical cues, as an osteoarthritis disease-relevant environmental perturbation, cause a critical shift in set points of methylation at transcriptionally active CpG sites in neo-cartilage organoids

超生理机械线索作为与骨关节炎疾病相关的环境扰动，导致新软骨类器官中转录活性 CpG 位点甲基化设定点发生关键转变

期刊:Clinical Epigenetics
影响因子:
doi:10.1186/s13148-024-01676-0
Niek G C Bloks #, Amanda Dicks #, Zainab Harissa, Rob G H H Nelissen, Ghazaleh Hajmousa, Yolande F M Ramos, Rodrigo Coutinho de Almeida, Farshid Guilak #, Ingrid Meulenbelt #
免疫
关节炎
发表日期：2024
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