日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Stabilization of the H5 clade 2.3.4.4b hemagglutinin improves vaccine-elicited neutralizing antibody responses in mice

稳定H5 2.3.4.4b分支血凝素可提高小鼠疫苗诱导的中和抗体反应。

Dosey, Annie; Dadonaite, Bernadeta; Gillespie, Rebecca A; Leaf, Elizabeth M; Vukovich, Matthew J; McGowan, Jackson; Grey, Emily; Muramatsu, Hiromi; Jun, Rachel H J; Pardi, Norbert; Kanekiyo, Masaru; Bloom, Jesse D; King, Neil P

Pleiotropic mutational effects on function and stability constrain the antigenic evolution of influenza haemagglutinin

多效性突变对功能和稳定性的影响限制了流感血凝素的抗原进化。

Yu, Timothy C; Kikawa, Caroline; Dadonaite, Bernadeta; Loes, Andrea N; Englund, Janet A; Bloom, Jesse D

High-throughput neutralization measurements correlate strongly with evolutionary success of human influenza strains

高通量中和试验结果与人类流感病毒株的进化成功密切相关。

Kikawa, Caroline; Loes, Andrea N; Huddleston, John; Figgins, Marlin D; Steinberg, Philippa; Griffiths, Tachianna; Drapeau, Elizabeth M; Peck, Heidi; Barr, Ian; Englund, Janet A; Hensley, Scott E; Bedford, Trevor; Bloom, Jesse D

Influenza hemagglutinin subtypes have different sequence constraints despite sharing extremely similar structures

尽管流感血凝素亚型的结构极其相似,但它们的序列限制却各不相同。

Ahn, Jenny J; Yu, Timothy C; Dadonaite, Bernadeta; Radford, Caelan E; Bloom, Jesse D

Clonal interference and changing selective pressures shape the escape of SARS-CoV-2 from hundreds of antibodies

克隆干扰和不断变化的选择压力影响着SARS-CoV-2病毒逃避数百种抗体的能力

Haddox, Hugh K; Abdel Aziz, Omar; Galloway, Jared G; Kent, Javen; Cooper, Cameron R; Jennings-Shaffer, Chris; Dumm, Will; Temple, Seth D; Bloom, Jesse D; Matsen, Frederick A 4th

Strain-specific differences in the response to egg-derived versus recombinant protein influenza vaccines

不同毒株对鸡蛋来源疫苗和重组蛋白流感疫苗的反应存在差异

Loes, Andrea N; Tarabi, Rosario Al; Li, Shuk H; Atkinson, Reilly K; Huddleston, John; Kikawa, Caroline; Griffths, Tachianna; Drapeau, Elizabeth M; Wong, Sook-San; Cheng, Samuel Ms; Leung, Nancy Hl; Cobey, Sarah; Cowling, Benjamin J; Bedford, Trevor; Hensley, Scott E; Bloom, Jesse D

Influenza hemagglutinin subtypes have different sequence constraints despite sharing extremely similar structures

尽管流感血凝素亚型具有极其相似的结构,但它们的序列限制却各不相同。

Ahn, Jenny J; Yu, Timothy C; Dadonaite, Bernadeta; Radford, Caelan E; Bloom, Jesse D

Complete definition of how mutations affect antibodies used to prevent RSV

完整阐述突变如何影响用于预防呼吸道合胞病毒(RSV)的抗体

Simonich, Cassandra A L; McMahon, Teagan E; Kampman, Lucas; Chu, Helen Y; Bloom, Jesse D

Evaluation of an H5 influenza virus mRNA-lipid nanoparticle (LNP) vaccine in lactating dairy cows

在泌乳奶牛中评估H5流感病毒mRNA-脂质纳米颗粒(LNP)疫苗

Santos, Jefferson J S; Souza, Carine K; Zanella, Giovana C; Goulart, Débora B; Arruda, Bailey; Boggiatto, Paola; Palmer, Mitchell V; Snyder, Celeste A; Kristula, Michaela A; Dickens, Charlene; Webb, Terry L; Atkinson, Reilly K; Dadonaite, Bernadeta; Dwivedi, Garima; Alameh, Mohamad-Gabriel; Bloom, Jesse D; Weissman, Drew; Althouse, Gary C; Baker, Amy L; Hensley, Scott E

Near real-time data on the human neutralizing antibody landscape to influenza virus as of early 2026 to inform vaccine-strain selection

近乎实时地获取截至2026年初人类流感病毒中和抗体分布情况的数据,以指导疫苗株的选择。

Kikawa, Caroline; Huddleston, John; Turner, Sam A; Loes, Andrea N; Liu, Jiaojiao; Gang, Sydney; Griffiths, Tachianna; Drapeau, Elizabeth M; Cowling, Benjamin J; Ho, Faith; Leung, Nancy H L; Englund, Janet A; Lacombe, Kristen; Watanabe, Shinji; Hasegawa, Hideki; Busch, Michael; Lanteri, Marion; Stone, Mars; Spencer, Bryan; Neher, Richard A; Smith, Derek J; Bedford, Trevor; Hensley, Scott E; Bloom, Jesse D