日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Competing forms of protein-protein association and DNA binding exhibited by BrxC from the BREX phage restriction system

BREX噬菌体限制系统中的BrxC表现出的蛋白质-蛋白质相互作用和DNA结合的竞争形式

Kaiser, Alexander J; Readshaw, Jennifer J; Doyle, Lindsey A; Puiu, Maria; Kelly, Abigail; McGuire, Sydney F; Peralta Acosta, Julieta; Vu, Duc; Nelson, Andrew; Smith, Darren L; Araújo-Bazán, Lidia; Arias-Palomo, Ernesto; Luyten, Yvette A; Stoddard, Barry L; Blower, Tim R; Kaiser, Brett K

Modularity of Zorya defense systems during phage inhibition

噬菌体抑制过程中佐里亚防御系统的模块化

Mariano, Giuseppina; Deme, Justin C; Readshaw, Jennifer J; Grobbelaar, Matthew J; Keenan, Mackenzie; El-Masri, Yasmin; Bamford, Lindsay; Songra, Suraj; Blower, Tim R; Palmer, Tracy; Lea, Susan M

Molecular basis of foreign DNA recognition by BREX anti-phage immunity system

BREX抗噬菌体免疫系统识别外源DNA的分子基础

Drobiazko, Alena; Adams, Myfanwy C; Skutel, Mikhail; Potekhina, Kristina; Kotovskaya, Oksana; Trofimova, Anna; Matlashov, Mikhail; Yatselenko, Daria; Maxwell, Karen L; Blower, Tim R; Severinov, Konstantin; Ghilarov, Dmitry; Isaev, Artem

PglZ from Type I BREX phage defence systems is a metal-dependent nuclease that forms a sub-complex with BrxB

来自 I 型 BREX 噬菌体防御系统的 PglZ 是一种金属依赖性核酸酶,可与 BrxB 形成亚复合物。

Readshaw, Jennifer J; Doyle, Lindsey A; Puiu, Maria; Kelly, Abigail; Nelson, Andrew; Kaiser, Alex J; McGuire, Sydney F; Peralta Acosta, Julieta; Smith, Darren L; Stoddard, Barry L; Kaiser, Brett K; Blower, Tim R

Ribonuclease toxin RelE1 inhibits growth of Mycobacterium tuberculosis through specific cleavage of the ribosomal anti-Shine-Dalgarno region

核糖核酸酶毒素RelE1通过特异性切割核糖体抗Shine-Dalgarno区抑制结核分枝杆菌的生长。

Han, Xue; Beck, Izaak N; Mansour, Moise; Arrowsmith, Tom J; Barriot, Roland; Chansigaud, Paul; Pagès, Carine; Hamze, Hussein; Akarsu, Hatice; Falquet, Laurent; Redder, Peter; Xu, Xibing; Blower, Tim R; Genevaux, Pierre

Regulation of a phage defence island by RptR, a novel repressor that controls restriction-modification systems in diverse bacteria.

RptR 是一种新型阻遏物,可控制多种细菌中的限制修饰系统,它能够调控噬菌体防御岛

Zhang YuGeng, Schuller Marion, Ahel Ivan, Blower Tim R, Exley Rachel M, Tang Christoph M

Modified DNA substrate selectivity by GmrSD-family Type IV restriction enzyme BrxU.

GmrSD家族IV型限制性内切酶BrxU改变了DNA底物的选择性

Readshaw Jennifer J, Lee Yan-Jiun, Weigele Peter, Blower Tim R

Nucleotidyltransferase toxin MenT extends aminoacyl acceptor ends of serine tRNAs to control Mycobacterium tuberculosis growth

核苷酸转移酶毒素 MenT 可延长丝氨酸 tRNA 的氨酰基受体末端,从而控制结核分枝杆菌的生长。

Xu, Xibing; Barriot, Roland; Voisin, Bertille; Arrowsmith, Tom J; Usher, Ben; Gutierrez, Claude; Han, Xue; Pagès, Carine; Redder, Peter; Blower, Tim R; Neyrolles, Olivier; Genevaux, Pierre

Using energy to go downhill-a genoprotective role for ATPase activity in DNA topoisomerase II

利用能量下坡——ATPase活性在DNA拓扑异构酶II中的基因保护作用

Bandak, Afif F; Blower, Tim R; Nitiss, Karin C; Shah, Viraj; Nitiss, John L; Berger, James M

Toxin release by conditional remodelling of ParDE1 from Mycobacterium tuberculosis leads to gyrase inhibition.

结核分枝杆菌 ParDE1 条件性重塑释放毒素,导致 DNA 回旋酶抑制

Beck Izaak N, Arrowsmith Tom J, Grobbelaar Matthew J, Bromley Elizabeth H C, Marles-Wright Jon, Blower Tim R