日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Prospective Evaluation of Structure-Based Simulations Reveal Their Ability to Predict the Impact of Kinase Mutations on Inhibitor Binding

前瞻性评估基于结构的模拟揭示了其预测激酶突变对抑制剂结合影响的能力

期刊:Journal of Physical Chemistry B
影响因子:2.9
doi:10.1021/acs.jpcb.4c07794
Singh, Sukrit; Gapsys, Vytautas; Aldeghi, Matteo; Schaller, David; Rangwala, Aziz M; White, Jessica B; Bluck, Joseph P; Scheen, Jenke; Glass, William G; Guo, Jiaye; Hayat, Sikander; de Groot, Bert L; Volkamer, Andrea; Christ, Clara D; Seeliger, Markus A; Chodera, John D
信号转导
发表日期：2025
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Prospective evaluation of structure-based simulations reveal their ability to predict the impact of kinase mutations on inhibitor binding

对基于结构的模拟的前瞻性评估表明，它们能够预测激酶突变对抑制剂结合的影响。

期刊:
影响因子:
doi:10.1101/2024.11.15.623861
Singh, Sukrit; Gapsys, Vytautas; Aldeghi, Matteo; Schaller, David; Rangwala, Aziz M; White, Jessica B; Bluck, Joseph P; Scheen, Jenke; Glass, William G; Guo, Jiaye; Hayat, Sikander; de Groot, Bert L; Volkamer, Andrea; Christ, Clara D; Seeliger, Markus A; Chodera, John D
信号转导
发表日期：2025
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Phenotypic screening converges on CDK9 inhibition as a therapeutic strategy in translocation renal cell carcinoma.

表型筛选结果表明，CDK9 抑制是易位性肾细胞癌的一种治疗策略

期刊:
影响因子:
doi:10.1101/2025.08.25.672235
Thapa Dharma R, Deodhar Riva, Skepner Adam, Konda Prathyusha, Zhou Meng, Bluck Joseph, Pichlo Christian, Cui Yantong, Stocker Paige, Khanna Prateek, Li Jiao, Tsai Jonathan M, Leed Alison, Gould Sandy, Alimova Maria, Friedrich Dhana, Cheah Jaime H, Rupaimoole Rajesha, Guicherit Oivin, Viswanathan Srinivas R
细胞生物学
肿瘤免疫
发表日期：2025
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Mutate and Conjugate: A Method to Enable Rapid In-Cell Target Validation

突变与偶联：一种实现快速细胞内靶点验证的方法

期刊:ACS Chemical Biology
影响因子:3.8
doi:10.1021/acschembio.3c00437
Thomas, Adam M; Serafini, Marta; Grant, Emma K; Coombs, Edward A J; Bluck, Joseph P; Schiedel, Matthias; McDonough, Michael A; Reynolds, Jessica K; Lee, Bernadette; Platt, Michael; Sharlandjieva, Vassilena; Biggin, Philip C; Duarte, Fernanda; Milne, Thomas A; Bush, Jacob T; Conway, Stuart J
细胞生物学
发表日期：2023
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Identification of Histone Peptide Binding Specificity and Small-Molecule Ligands for the TRIM33α and TRIM33β Bromodomains

TRIM33α和TRIM33β溴结构域的组蛋白肽结合特异性及小分子配体的鉴定

期刊:ACS Chemical Biology
影响因子:3.8
doi:10.1021/acschembio.2c00266
Sekirnik, Angelina R; Reynolds, Jessica K; See, Larissa; Bluck, Joseph P; Scorah, Amy R; Tallant, Cynthia; Lee, Bernadette; Leszczynska, Katarzyna B; Grimley, Rachel L; Storer, R Ian; Malattia, Marta; Crespillo, Sara; Caria, Sofia; Duclos, Stephanie; Hammond, Ester M; Knapp, Stefan; Morris, Garrett M; Duarte, Fernanda; Biggin, Philip C; Conway, Stuart J
发表日期：2022
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