Design of a "Two-in-One" Mutant-Selective Epidermal Growth Factor Receptor Inhibitor That Spans the Orthosteric and Allosteric Sites
跨越正构和变构位点的“二合一”突变选择性表皮生长因子受体抑制剂的设计
期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.1c00848
Florian Wittlinger, David E Heppner, Ciric To, Marcel Günther, Bo Hee Shin, Jaimin K Rana, Anna M Schmoker, Tyler S Beyett, Lena M Berger, Benedict-Tilman Berger, Nicolas Bauer, James D Vasta, Cesear R Corona, Matthew B Robers, Stefan Knapp, Pasi A Jänne, Michael J Eck, Stefan A Laufer
