EZH2 inhibition mitigates HIV immune evasion, reduces reservoir formation, and promotes skewing of CD8(+) T cells toward less-exhausted phenotypes.
EZH2 抑制可减轻 HIV 免疫逃逸，减少病毒库形成，并促进 CD8(+) T 细胞向耗竭程度较低的表型转变。
期刊:Cell Reports
影响因子:6.9
doi:10.1016/j.celrep.2025.115652
Gramatica Andrea, Miller Itzayana G, Ward Adam R, Khan Farzana, Kemmer Tyler J, Weiler Jared, Huynh Tan Thinh, Zumbo Paul, Kurland Andrew P, Leyre Louise, Ren Yanqin, Klevorn Thais, Copertino Dennis C, Chukwukere Uchenna, Levinger Callie, Dilling Thomas R, Linden Noemi, Board Nathan L, Falling Iversen Emma, Terry Sandra, Mota Talia M, Bedir Seden, Clayton Kiera L, Bosque Alberto, MacLaren Ehui Lynsay, Kovacs Colin, Betel Doron, Johnson Jeffry R, Paiardini Mirko, Danesh Ali, Jones R Brad
