Saturation Mutagenesis of the Antithrombin Reactive Center Loop P14 Residue Supports a Three-step Mechanism of Heparin Allosteric Activation Involving Intermediate and Fully Activated States
抗凝血酶反应中心环 P14 残基的饱和突变支持肝素变构激活的三步机制,该机制涉及中间激活态和完全激活态。
期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.M115.678839
Roth, Ryan; Swanson, Richard; Izaguirre, Gonzalo; Bock, Susan C; Gettins, Peter G W; Olson, Steven T