日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Five Years of Ublituximab in Multiple Sclerosis: ULTIMATE I and II Open-Label Extension Study

Ublituximab治疗多发性硬化症五年:ULTIMATE I 和 II 开放标签扩展研究

Cree, Bruce A C; Fox, Edward; Hartung, Hans-Peter; Alvarez, Enrique; Qian, Peiqing; Wray, Sibyl; Robertson, Derrick; Selmaj, Krzysztof; Wynn, Daniel; Mok, Koby; Rowland, Chris; Bodhinathan, Karthik; Sportelli, Peter; Miskin, Hari P; Steinman, Lawrence

Long-term clinical outcomes in patients with multiple sclerosis who are initiating disease-modifying therapy with natalizumab compared with BRACETD first-line therapies

与 BRACETD 一线疗法相比,接受那他珠单抗疾病修饰疗法治疗的多发性硬化症患者的长期临床疗效

Butzkueven, Helmut; Kalincik, Tomas; Patti, Francesco; Slee, Mark; Weinstock-Guttman, Bianca; Buzzard, Katherine; Skibina, Olga; Alroughani, Raed; Prat, Alexandre; Girard, Marc; Horakova, Dana; Havrdova, Eva Kubala; Van der Walt, Anneke; Eichau, Sara; Hyde, Robert; Campbell, Nolan; Bodhinathan, Karthik; Spelman, Tim

Improvements in no evidence of disease activity with ublituximab vs. teriflunomide in the ULTIMATE phase 3 studies in relapsing multiple sclerosis

在复发型多发性硬化症的 ULTIMATE 3 期研究中,ublituximab 与 teriflunomide 相比,在无疾病活动证据方面有所改善

Alvarez, Enrique; Steinman, Lawrence; Fox, Edward J; Hartung, Hans-Peter; Qian, Peiqing; Wray, Sibyl; Robertson, Derrick; Selmaj, Krzysztof; Wynn, Daniel; Mok, Koby; Xu, Yihuan; Bodhinathan, Karthik; Miskin, Hari P; Cree, Bruce A C

α-Synuclein Oligomers Induce Glutamate Release from Astrocytes and Excessive Extrasynaptic NMDAR Activity in Neurons, Thus Contributing to Synapse Loss

α-突触核蛋白寡聚体诱导星形胶质细胞释放谷氨酸,并增加神经元中突触外 NMDAR 活性,从而导致突触丢失

Dorit Trudler, Sara Sanz-Blasco, Yvonne S Eisele, Swagata Ghatak, Karthik Bodhinathan, Mohd Waseem Akhtar, William P Lynch, Juan C Piña-Crespo, Maria Talantova, Jeffery W Kelly, Stuart A Lipton

Dynamic role of the tether helix in PIP(2)-dependent gating of a G protein-gated potassium channel

系绳螺旋在 PIP(2) 依赖性 G 蛋白门控钾通道门控中的动态作用

Lacin, Emre; Aryal, Prafulla; Glaaser, Ian W; Bodhinathan, Karthik; Tsai, Eric; Marsh, Nidaa; Tucker, Stephen J; Sansom, Mark S P; Slesinger, Paul A

Alcohol modulation of G-protein-gated inwardly rectifying potassium channels: from binding to therapeutics

酒精对G蛋白门控内向整流钾通道的调节:从结合到治疗

Bodhinathan, Karthik; Slesinger, Paul A

Molecular mechanism underlying ethanol activation of G-protein-gated inwardly rectifying potassium channels

乙醇激活G蛋白门控内向整流钾通道的分子机制

Bodhinathan, Karthik; Slesinger, Paul A

Ras-association domain of sorting Nexin 27 is critical for regulating expression of GIRK potassium channels

分选连接蛋白27的Ras关联结构域对于调节GIRK钾通道的表达至关重要。

Balana, Bartosz; Bahima, Laia; Bodhinathan, Karthik; Taura, Jaume J; Taylor, Natalie M; Nettleton, Margaret Y; Ciruela, Francisco; Slesinger, Paul A

Enhanced expression of Pctk1, Tcf12 and Ccnd1 in hippocampus of rats: Impact on cognitive function, synaptic plasticity and pathology

大鼠海马中 Pctk1、Tcf12 和 Ccnd1 表达增强:对认知功能、突触可塑性和病理的影响

Ke Wu, Shoudong Li, Karthik Bodhinathan, Craig Meyers, Weijun Chen, Martha Campbell-Thompson, Lauren McIntyre, Thomas C Foster, Nicholas Muzyczka, Ashok Kumar

Intracellular redox state alters NMDA receptor response during aging through Ca2+/calmodulin-dependent protein kinase II

细胞内氧化还原状态通过 Ca2+/钙调蛋白依赖性蛋白激酶 II 改变衰老过程中的 NMDA 受体反应

Karthik Bodhinathan, Ashok Kumar, Thomas C Foster