日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Frequency of S492R mutations in the epidermal growth factor receptor: analysis of plasma DNA from patients with metastatic colorectal cancer treated with panitumumab or cetuximab monotherapy

表皮生长因子受体S492R突变频率:对接受帕尼单抗或西妥昔单抗单药治疗的转移性结直肠癌患者血浆DNA的分析

Price, Timothy; Ang, Agnes; Boedigheimer, Michael; Kim, Tae Won; Li, Jin; Cascinu, Stefano; Ruff, Paul; Satya Suresh, Attili; Thomas, Anne; Tjulandin, Sergei; Peeters, Marc

Dynamic molecular analysis and clinical correlates of tumor evolution within a phase II trial of panitumumab-based therapy in metastatic colorectal cancer

在帕尼单抗治疗转移性结直肠癌的II期临床试验中,对肿瘤演变进行动态分子分析和临床相关性研究

Siena, S; Sartore-Bianchi, A; Garcia-Carbonero, R; Karthaus, M; Smith, D; Tabernero, J; Van Cutsem, E; Guan, X; Boedigheimer, M; Ang, A; Twomey, B; Bach, B A; Jung, A S; Bardelli, A

Brief Report: Pharmacodynamics, Safety, and Clinical Efficacy of AMG 811, a Human Anti-Interferon-γ Antibody, in Patients With Discoid Lupus Erythematosus

简报:人源抗干扰素-γ抗体AMG 811在盘状红斑狼疮患者中的药效学、安全性和临床疗效

Werth, Victoria P; Fiorentino, David; Sullivan, Barbara A; Boedigheimer, Michael J; Chiu, Kit; Wang, Christine; Arnold, Gregory E; Damore, Michael A; Bigler, Jeannette; Welcher, Andrew A; Russell, Chris B; Martin, David A; Chung, James B

Safety, pharmacokinetics and pharmacodynamics of AMG 811, an anti-interferon-γ monoclonal antibody, in SLE subjects without or with lupus nephritis

在患有或不患有狼疮性肾炎的系统性红斑狼疮(SLE)患者中,抗干扰素-γ单克隆抗体AMG 811的安全性、药代动力学和药效学研究

Boedigheimer, Michael J; Martin, David A; Amoura, Zahir; Sánchez-Guerrero, Jorge; Romero-Diaz, Juanita; Kivitz, Alan; Aranow, Cynthia; Chan, Tak Mao; Chong, Yip Boon; Chiu, Kit; Wang, Christine; Sohn, Winnie; Arnold, Gregory E; Damore, Michael A; Welcher, Andrew A; Sullivan, Barbara A; Kotzin, Brian L; Chung, James B

Impact of tumour RAS/BRAF status in a first-line study of panitumumab + FOLFIRI in patients with metastatic colorectal cancer

肿瘤 RAS/BRAF 状态对帕尼单抗联合 FOLFIRI 一线治疗转移性结直肠癌患者的影响

Karthaus, Meinolf; Hofheinz, Ralf-Dieter; Mineur, Laurent; Letocha, Henry; Greil, Richard; Thaler, Josef; Fernebro, Eva; Oliner, Kelly S; Boedigheimer, Michael; Twomey, Brian; Zhang, Ying; Demonty, Gaston; Köhne, Claus-Henning

Transcriptome analysis reveals manifold mechanisms of cyst development in ADPKD

转录组分析揭示了 ADPKD 囊肿发展的多种机制

Rita M C de Almeida, Sherry G Clendenon, William G Richards, Michael Boedigheimer, Michael Damore, Sandro Rossetti, Peter C Harris, Britney-Shea Herbert, Wei Min Xu, Angela Wandinger-Ness, Heather H Ward, James A Glazier, Robert L Bacallao

Blockade of interferon-γ normalizes interferon-regulated gene expression and serum CXCL10 levels in patients with systemic lupus erythematosus

阻断干扰素-γ可使系统性红斑狼疮患者的干扰素调节基因表达和血清CXCL10水平恢复正常

Andrew A Welcher ,Michael Boedigheimer ,Alan J Kivitz ,Zahir Amoura ,Jill Buyon ,Alla Rudinskaya ,Kevin Latinis ,Kit Chiu ,Kelly S Oliner ,Michael A Damore ,Gregory E Arnold ,Winnie Sohn ,Narendra Chirmule ,Lovely Goyal ,Christopher Banfield ,James B Chung

Identifying the determinants of response to MDM2 inhibition.

确定MDM2抑制反应的决定因素

Saiki Anne Y, Caenepeel Sean, Cosgrove Elissa, Su Cheng, Boedigheimer Michael, Oliner Jonathan D

Evaluation of an integrated clinical workflow for targeted next-generation sequencing of low-quality tumor DNA using a 51-gene enrichment panel

使用包含51个基因的富集panel对低质量肿瘤DNA进行靶向二代测序,并评估其整合临床工作流程。

Choudhary, Ashish; Mambo, Elizabeth; Sanford, Tiffany; Boedigheimer, Michael; Twomey, Brian; Califano, Joseph; Hadd, Andrew; Oliner, Kelly S; Beaudenon, Sylvie; Latham, Gary J; Adai, Alex T

Chondro/osteoblastic and cardiovascular gene modulation in human artery smooth muscle cells that calcify in the presence of phosphate and calcitriol or paricalcitol

在磷酸盐和骨化三醇或帕立骨化醇存在下,人动脉平滑肌细胞钙化过程中软骨/成骨细胞和心血管基因的调控

Shalhoub, V; Shatzen, E M; Ward, S C; Young, J-I; Boedigheimer, M; Twehues, L; McNinch, J; Scully, S; Twomey, B; Baker, D; Kiaei, P; Damore, M A; Pan, Z; Haas, K; Martin, D