日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Treatment with the CCR5 antagonist OB-002 reduces lung pathology, but does not prevent disease in a Syrian hamster model of SARS-CoV-2 infection

在SARS-CoV-2感染的叙利亚仓鼠模型中,使用CCR5拮抗剂OB-002治疗可减轻肺部病理,但不能预防疾病。

Warner, Bryce M; Vendramelli, Robert; Boese, Amrit S; Audet, Jonathan; Tailor, Nikesh; Meilleur, Courtney; Glowach, Nathan; Willman, Marnie; Truong, Thang; Moffat, Estella; Tierney, Kevin; Kosak, Beata; Dhanidina, Irfan; Engstrom, Jarret; Korczak, Bozena; McGowan, Ian; Embury-Hyatt, Carissa; Kobasa, Darwyn

Delayed treatment of cynomolgus macaques with a FVM04/CA45 monoclonal antibody cocktail provides complete protection against lethal Sudan virus infection

对食蟹猴延迟使用FVM04/CA45单克隆抗体混合物进行治疗,可完全预防致命的苏丹病毒感染。

Chan, Mable; Warner, Bryce M; Audet, Jonathan; Barker, Douglas; Tailor, Nikesh; Vendramelli, Robert; Truong, Thang; Tierney, Kevin; Boese, Amrit S; Qiu, Honguy; Holtsberg, Frederick W; Aman, Javad; Kodihalli, Shantha; Kobasa, Darwyn

SARS-CoV-2 infection results in a unique lung proteome long after virus resolution in the hamster.

SARS-CoV-2 感染会导致仓鼠肺部蛋白质组在病毒清除后很长时间内仍保持独特性

Boese Amrit S, Warner Bryce M, McQueen Peter, Vendramelli Robert, Tailor Nikesh, Griffin Bryan D, Chan Mable, Audet Jonathan, Leung Anders, McCorrister Stuart, Grant Chris, Westmacott Garrett, Kobasa Darwyn