日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

A Phase Ib/II study of IGF-neutralising antibody xentuzumab with enzalutamide in metastatic castration-resistant prostate cancer

IGF 中和抗体 xentuzumab 与恩杂鲁胺治疗转移性去势抵抗性前列腺癌的 Ib/II 期研究

期刊:British Journal of Cancer
影响因子:6.4
doi:10.1038/s41416-023-02380-1
Valentine M Macaulay, Simon Lord, Syed Hussain, José Pablo Maroto, Robert Hugh Jones, Miguel Ángel Climent, Natalie Cook, Chia-Chi Lin, Shian-Shiang Wang, Diletta Bianchini, Mark Bailey, Laura Schlieker, Thomas Bogenrieder, Johann de Bono
肿瘤
前列腺癌
IHC
发表日期：2023
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CHK1 inhibition exacerbates replication stress induced by IGF blockade

CHK1 抑制会加剧 IGF 阻断引起的复制压力

期刊:Oncogene
影响因子:6.9
doi:10.1038/s41388-021-02080-1
Xiaoning Wu, Elena Seraia, Stephanie B Hatch, Xiao Wan, Daniel V Ebner, Francesca Aroldi, Yanyan Jiang, Anderson J Ryan, Thomas Bogenrieder, Ulrike Weyer-Czernilofsky, Guillaume Rieunier #, Valentine M Macaulay #
AROS
发表日期：2022
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Phase 1b Open-Label Trial of Afatinib Plus Xentuzumab (BI 836845) in Patients With EGFR Mutation-Positive NSCLC After Progression on EGFR Tyrosine Kinase Inhibitors

阿法替尼联合Xentuzumab（BI 836845）治疗EGFR酪氨酸激酶抑制剂治疗进展后的EGFR突变阳性非小细胞肺癌患者的1b期开放标签试验

期刊:JTO Clinical and Research Reports
影响因子:3.5
doi:10.1016/j.jtocrr.2021.100206
Park, Keunchil; Tan, Daniel Shao Weng; Su, Wu-Chou; Cho, Byoung Chul; Kim, Sang-We; Lee, Ki Hyeong; Wang, Chin-Chou; Seto, Takashi; Huang, Dennis Chin-Lun; Jung, Helen Hayoun; Hsu, Ming-Chi; Bogenrieder, Thomas; Lin, Chia-Chi
肺癌
肿瘤
肿瘤免疫
信号转导
EGF
EGFR
细胞生物学
发表日期：2021
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Antitumor Activity of the IGF-1/IGF-2-Neutralizing Antibody Xentuzumab (BI 836845) in Combination with Enzalutamide in Prostate Cancer Models

IGF-1/IGF-2中和抗体Xentuzumab（BI 836845）联合恩扎卢胺在前列腺癌模型中的抗肿瘤活性

期刊:Molecular Cancer Therapeutics
影响因子:5.5
doi:10.1158/1535-7163.MCT-19-0378
Weyer-Czernilofsky, Ulrike; Hofmann, Marco H; Friedbichler, Katrin; Baumgartinger, Rosa; Adam, Paul J; Solca, Flavio; Kraut, Norbert; Nguyen, Holly M; Corey, Eva; Liu, Gang; Sprenger, Cynthia C; Plymate, Stephen R; Bogenrieder, Thomas
肿瘤
肿瘤免疫
IGF-2
IGF-1
前列腺癌
发表日期：2020
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Nuclear IGF1R Interacts with Regulatory Regions of Chromatin to Promote RNA Polymerase II Recruitment and Gene Expression Associated with Advanced Tumor Stage

核 IGF1R 与染色质调控区相互作用，促进 RNA 聚合酶 II 募集和与晚期肿瘤阶段相关的基因表达

期刊:Cancer Research
影响因子:12.5
doi:10.1158/0008-5472.CAN-17-3498
Tamara Aleksic, Nicki Gray, Xiaoning Wu, Guillaume Rieunier, Eliot Osher, Jack Mills, Clare Verrill, Richard J Bryant, Cheng Han, Kathryn Hutchinson, Adam G Lambert, Rajeev Kumar, Freddie C Hamdy, Ulrike Weyer-Czernilofsky, Michael P Sanderson, Thomas Bogenrieder, Stephen Taylor, Valentine M Macaula
肿瘤
发表日期：2018
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Blockade of insulin-like growth factors increases efficacy of paclitaxel in metastatic breast cancer

阻断胰岛素样生长因子可提高紫杉醇治疗转移性乳腺癌的疗效

期刊:Oncogene
影响因子:6.9
doi:10.1038/s41388-017-0115-x
Lucy Ireland ，Almudena Santos ，Fiona Campbell ，Carlos Figueiredo ，Dean Hammond ，Lesley G Ellies ，Ulrike Weyer-Czernilofsky ，Thomas Bogenrieder ，Michael Schmid ，Ainhoa Mielgo
免疫/内分泌
乳腺癌
肿瘤
肿瘤免疫
发表日期：2018
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Regulation of proliferation and invasion by the IGF signalling pathway in Epstein-Barr virus-positive gastric cancer

IGF信号通路对Epstein-Barr病毒阳性胃癌增殖和侵袭的调控

期刊:Journal of Cellular and Molecular Medicine
影响因子:4.3
doi:10.1111/jcmm.13859
Inhye Jeong, Sun Kyoung Kang, Woo Sun Kwon, Hyun Jeong Kim, Kyoo Hyun Kim, Hyun Myong Kim, Andre Lee, Suk Kyeong Lee, Thomas Bogenrieder, Hyun Cheol Chung, Sun Young Rha
肿瘤
胃癌
发表日期：2018
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Insulin-Like Growth Factor (IGF) Pathway Targeting in Cancer: Role of the IGF Axis and Opportunities for Future Combination Studies

癌症中胰岛素样生长因子（IGF）通路靶向治疗：IGF轴的作用及未来联合研究的机遇

期刊:Targeted Oncology
影响因子:4
doi:10.1007/s11523-017-0514-5
Simpson, Aaron; Petnga, Wilfride; Macaulay, Valentine M; Weyer-Czernilofsky, Ulrike; Bogenrieder, Thomas
信号转导
肿瘤
肿瘤免疫
免疫/内分泌
发表日期：2017
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Non-reproducible sequence artifacts in FFPE tissue: an experience report

FFPE组织中不可重复的序列伪影：经验报告

期刊:Journal of Cancer Research and Clinical Oncology
影响因子:2.8
doi:10.1007/s00432-017-2399-1
Ofner, Richard; Ritter, Cathrin; Ugurel, Selma; Cerroni, Lorenzo; Stiller, Mathias; Bogenrieder, Thomas; Solca, Flavio; Schrama, David; Becker, Jürgen C
发表日期：2017
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Chemoresistance in Pancreatic Cancer Is Driven by Stroma-Derived Insulin-Like Growth Factors

胰腺癌的化学耐药性是由基质衍生的胰岛素样生长因子驱动的

期刊:Cancer Research
影响因子:12.5
doi:10.1158/0008-5472.CAN-16-1201
Lucy Ireland #, Almudena Santos #, Muhammad S Ahmed, Carolyn Rainer, Sebastian R Nielsen, Valeria Quaranta, Ulrike Weyer-Czernilofsky, Danielle D Engle, Pedro A Perez-Mancera, Sarah E Coupland, Azzam Taktak, Thomas Bogenrieder, David A Tuveson, Fiona Campbell, Michael C Schmid, Ainhoa Mielgo
代谢
肿瘤
胰腺癌
发表日期：2016
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