日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A Bacteroides fragilis protease activates host PAR(2) to induce intestinal pain and inflammation.

脆弱拟杆菌蛋白酶激活宿主PAR(2),诱发肠道疼痛和炎症。

Lakemeyer Markus, Latorre Rocco, Blazkova Kristyna, Wood Hannah M, Jensen Dane D, Shakil Nayab, Thomas Scott C, Saxena Deepak, Mulpuri Yatendra, Poolman David, Duran Paz, Keller Laura J, Reed David E, Schmidt Brian L, Jiménez-Vargas Néstor N, Xu Fangxi, Lomax Alan E, Bunnett Nigel W, Bogyo Matthew

Identification of covalent inhibitors of Staphylococcus aureus serine hydrolases important for virulence and biofilm formation

鉴定对金黄色葡萄球菌毒力和生物膜形成至关重要的丝氨酸水解酶的共价抑制剂

Upadhyay, Tulsi; Woods, Emily C; Dela Ahator, Stephen; Julin, Kjersti; Faucher, Franco F; Uddin, Md Jalal; Hollander, Marijn J; Pedowitz, Nichole J; Abegg, Daniel; Hammond, Isabella; Eke, Ifeanyichukwu E; Wang, Sijie; Chen, Shiyu; Bennett, John M; Jo, Jeyun; Lentz, Christian S; Adibekian, Alexander; Fellner, Matthias; Bogyo, Matthew

Identification of Covalent Cyclic Peptide Inhibitors Targeting Protein-Protein Interactions Using Phage Display

利用噬菌体展示技术鉴定靶向蛋白质-蛋白质相互作用的共价环肽抑制剂

Wang, Sijie; Faucher, Franco F; Bertolini, Matilde; Kim, Heeyoung; Yu, Bingchen; Cao, Li; Roeltgen, Katharina; Lovell, Scott; Shanker, Varun; Boyd, Scott D; Wang, Lei; Bartenschlager, Ralf; Bogyo, Matthew

An mRNA Display Approach for Covalent Targeting of a Staphylococcus aureus Virulence Factor

一种用于共价靶向金黄色葡萄球菌毒力因子的mRNA展示方法

Wang, Sijie; Woods, Emily C; Jo, Jeyun; Zhu, Jiyun; Hansel-Harris, Althea; Holcomb, Matthew; Llanos, Manuel; Pedowitz, Nichole J; Upadhyay, Tulsi; Bennett, John; Fellner, Matthias; Park, Ki Wan; Zhang, Anna; Valdez, Tulio A; Forli, Stefano; Chan, Alix I; Cunningham, Christian N; Bogyo, Matthew

Macrocyclic Phage Display for Identification of Selective Protease Substrates

大环噬菌体展示技术用于鉴定选择性蛋白酶底物

Faucher, Franco F; Blažková, Kristýna; Lovell, Scott; Bertolini, Matilde; Herrero-Bourdieu, Juan; Cosco, Emily D; Bogyo, Matthew; Barniol-Xicota, Marta

The Present and Future of Genetic Sequencing as Applied to Diagnosis and Management in Rheumatology

基因测序在风湿病诊断和治疗中的现状与未来

Liebowitz, Jason; Milo Rasouly, Hila; Bogyo, Kelsie; Petukhova, Lynn; Bernstein, Elana J; Schwartz, Daniella M; Grayson, Peter C; Beck, David; Luo, Yiming

Nanomedicines targeting protease-activated receptor 2 in endosomes provide sustained analgesia

靶向内体中蛋白酶激活受体2的纳米药物可提供持续镇痛作用

Teng, Shavonne L; Latorre, Rocco; Bhansali, Divya; Lewis, Parker K; Pollard, Rachel E; Peach, Chloe J; Sokrat, Badr; Thanigai Arasu, Gokul Sriman; Chiu, Tracy; Duran, Paz; Jimenez-Vargas, Nestor N; Mocherniak, Abby; Bogyo, Matthew; Gaspari, Michael M; Vanner, Stephen J; Pinkerton, Nathalie M; W Leong, Kam; Schmidt, Brian L; Jensen, Dane D; Bunnett, Nigel W

Mycobacteriophage Functionalized Magnetic Nanocrystal Clusters for Highly Sensitive and Rapid Detection of Mycobacterium tuberculosis

用于高灵敏度和快速检测结核分枝杆菌的分枝杆菌噬菌体功能化磁性纳米晶簇

Xiao, Zhen; Yen, Charles; Wang, Ting; Ibrahim, Jawad; Fu, Qunfeng; Dai, Sheng-Yao; Hajfathalian, Maryam; Murugesan, Kanagavel; Banaei, Niaz; Bogyo, Matthew; Rao, Jianghong

Chemical strategies for targeting lipid pathways in bacterial pathogens

针对细菌病原体脂质代谢途径的化学策略

Carter, Alyssa M; Woods, Emily C; Bogyo, Matthew

A robust fluorogenic substrate for chikungunya virus protease (nsP2) activity

一种用于检测基孔肯雅病毒蛋白酶(nsP2)活性的强效荧光底物

Makhaik, Sparsh; Rut, Wioletta; Choudhary, Shruti; Upadhyay, Tulsi; Hao, Chenzhou; Westberg, Michael; Bobst, Cedric; Yoo, Euna; Fejzo, Jasna; Lin, Michael Z; Bogyo, Matthew; Thompson, Paul; Drag, Marcin; Hardy, Jeanne A