日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Chromatin insulation orchestrates matrix metalloproteinase gene cluster expression reprogramming in aggressive breast cancer tumors

染色质绝缘体调控侵袭性乳腺癌肿瘤中基质金属蛋白酶基因簇的表达重编程

Llinàs-Arias, Pere; Ensenyat-Mendez, Miquel; Íñiguez-Muñoz, Sandra; Orozco, Javier I J; Valdez, Betsy; Salomon, Matthew P; Matsuba, Chikako; Solivellas-Pieras, Maria; Bedoya-López, Andrés F; Sesé, Borja; Mezger, Anja; Ormestad, Mattias; Unzueta, Fernando; Strand, Siri H; Boiko, Alexander D; Hwang, E Shelley; Cortés, Javier; DiNome, Maggie L; Esteller, Manel; Lupien, Mathieu; Marzese, Diego M

CD271 is a molecular switch with divergent roles in melanoma and melanocyte development.

CD271 是一种分子开关,在黑色素瘤和黑色素细胞发育中发挥着不同的作用

Filipp Fabian V, Li Chen, Boiko Alexander D

Therapeutic implications of melanoma heterogeneity

黑色素瘤异质性的治疗意义

Hachey, Stephanie J; Boiko, Alexander D

A systematic search for downstream mediators of tumor suppressor function of p53 reveals a major role of BTG2 in suppression of Ras-induced transformation

对p53肿瘤抑制功能的下游介质进行系统性研究,揭示了BTG2在抑制Ras诱导的转化中发挥着重要作用。

Boiko, Alexander D; Porteous, Sarah; Razorenova, Olga V; Krivokrysenko, Vadim I; Williams, Bryan R; Gudkov, Andrei V

Secreted transforming growth factor beta2 activates NF-kappaB, blocks apoptosis, and is essential for the survival of some tumor cells

分泌型转化生长因子β2激活NF-κB,抑制细胞凋亡,对某些肿瘤细胞的存活至关重要。

Lu, Tao; Burdelya, Lyudmila G; Swiatkowski, Shannon M; Boiko, Alexander D; Howe, Philip H; Stark, George R; Gudkov, Andrei V

Cdk4 disruption renders primary mouse cells resistant to oncogenic transformation, leading to Arf/p53-independent senescence

Cdk4 破坏使小鼠原代细胞对致癌转化产生抵抗力,导致 Arf/p53 非依赖性衰老。

Zou, Xianghong; Ray, Dipankar; Aziyu, Aileen; Christov, Konstantin; Boiko, Alexander D; Gudkov, Andrei V; Kiyokawa, Hiroaki